| Non-peptidic cruzain inhibitors with trypanocidal activity discovered by virtual screening and in vitro assay HJ Wiggers, JR Rocha, WB Fernandes, R Sesti-Costa, ZA Carneiro, ... PLoS neglected tropical diseases 7 (8), e2370, 2013 | 104 | 2013 |
| Effects of organic solvents on the enzyme activity of Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase in calorimetric assays HJ Wiggers, J Cheleski, A Zottis, G Oliva, AD Andricopulo, CA Montanari Analytical biochemistry 370 (1), 107-114, 2007 | 64 | 2007 |
| Novel insights for dihydroorotate dehydrogenase class 1A inhibitors discovery J Cheleski, JR Rocha, MP Pinheiro, HJ Wiggers, ABF da Silva, ... European journal of medicinal chemistry 45 (12), 5899-5909, 2010 | 63 | 2010 |
| Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding DBB Trivella, L Bleicher, L de Castro Palmieri, HJ Wiggers, CA Montanari, ... Journal of structural biology 170 (3), 522-531, 2010 | 50 | 2010 |
| Curcumin, a multitarget phytochemical: challenges and perspectives HJ Wiggers, S Zaioncz, J Cheleski, RM Mainardes, NM Khalil Studies in Natural Products Chemistry 53, 243-276, 2017 | 40 | 2017 |
| Integration of ligand‐and target‐based virtual screening for the discovery of Cruzain inhibitors HJ Wiggers, JR Rocha, J Cheleski, CA Montanari Molecular Informatics 30 (6‐7), 565-578, 2011 | 35 | 2011 |
| The low-cost Shifter microscope stage transforms the speed and robustness of protein crystal harvesting ND Wright, P Collins, L Koekemoer, T Krojer, R Talon, E Nelson, M Ye, ... Acta Crystallographica Section D: Structural Biology 77 (1), 62-74, 2021 | 34 | 2021 |
| Kinetic mechanism and catalysis of Trypanosoma cruzi dihydroorotate dehydrogenase enzyme evaluated by isothermal titration calorimetry J Cheleski, HJ Wiggers, AP Citadini, AJ da Costa Filho, MC Nonato, ... Analytical biochemistry 399 (1), 13-22, 2010 | 20 | 2010 |
| Expression, purification and kinetic characterization of His-tagged glyceraldehyde-3-phosphate dehydrogenase from Trypanosoma cruzi J Cheleski, RF Freitas, HJ Wiggers, JR Rocha, APU de Araújo, ... Protein Expression and Purification 76 (2), 190-196, 2011 | 19 | 2011 |
| Quercetin-crosslinked chitosan films for controlled release of antimicrobial drugs HJ Wiggers, P Chevallier, F Copes, FH Simch, F da Silva Veloso, ... Frontiers in Bioengineering and Biotechnology 10, 814162, 2022 | 17 | 2022 |
| Identification of anti-inflammatory and anti-hypertensive drugs as inhibitors of bacterial diguanylate cyclases HJ Wiggers, E Crusca, ÉED Silva, J Cheleski, NU Torres, MVAS Navarro Journal of the Brazilian Chemical Society 29 (2), 297-309, 2018 | 11 | 2018 |
| Dressings produced from PVA nanofibers containing chloramphenicol GN Fraga, DC Dragunski, BH Vilsinski, CK da Silva Azevedo, HJ Wiggers, ... Colloids and Surfaces A: Physicochemical and Engineering Aspects 674, 131760, 2023 | 9 | 2023 |
| Prolonged Antibacterial Activity in Tannic Acid–Iron Complexed Chitosan Films for Medical Device Applications P Chevallier, HJ Wiggers, F Copes, C Zorzi Bueno, D Mantovani Nanomaterials 13 (3), 484, 2023 | 6 | 2023 |
| A new bianthron glycoside as inhibitor of Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase activity EMS de Macedo, HJ Wiggers, MGV Silva, R Braz-Filho, AD Andricopulo, ... Journal of the Brazilian Chemical Society 20 (5), 947-953, 2009 | 6 | 2009 |
| Structural and thermodynamic studies of two centrin isoforms from Blastocladiella emersonii upon calcium binding AI Camargo, HJ Wiggers, JCP Damalio, APU Araujo, KF Ribichich, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (12), 2823-2831, 2013 | 4 | 2013 |
| A new bianthron glycoside as inhibitor of Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase activity E Macedo, HJ Wiggers, MGV Silva, R Braz-Filho, AD Andricopulo, ... Journal of the Brazilian Chemical Society 20, 947-953, 2009 | 4 | 2009 |
| Planejamento de inibidores da enzima gliceraldeído-3-fosfato desidrogenase de Trypanosoma cruzi por biocalorimetria HJ Wiggers Universidade de São Paulo, 2007 | 3 | 2007 |
| Isothermal titration calorimetry as a tool for determining kinetic parameters of Trypanosoma cruzi dihydroorotate dehydrogenase enzyme J Cheleski, AP Citadini, HJ Wiggers, AJ Costa Filho, MC Nonato, ... Abstract, 2008 | 1 | 2008 |
| Thermodynamic signature of two novel cysteine protease inhibitors-cystatins, determined by isothermal titration calorimetry J Cheleski, HJ Wiggers, A Gianotti, FH Silva, CA Montanari Abstract Book, 2006 | 1 | 2006 |
| Alkaline earth metal-based coordination polymers produced with benzophenone-3, 3′, 4, 4′-tetracarboxylate: synthesis and application ÉF Poruczinski, DJ Welzel, TA Grigolo, MN dos Santos, JCM Willig, ... Polymer Bulletin, 1-16, 2024 | | 2024 |
