Immunoglobulin class-switch DNA recombination: induction, targeting and beyond Z Xu, H Zan, EJ Pone, T Mai, P Casali Nature Reviews Immunology 12 (7), 517-531, 2012 | 595 | 2012 |
Elucidation of exosome migration across the blood–brain barrier model in vitro CC Chen, L Liu, F Ma, CW Wong, XE Guo, JV Chacko, HP Farhoodi, ... Cellular and molecular bioengineering 9 (4), 509-529, 2016 | 459 | 2016 |
Stem cell-derived exosomes as nanotherapeutics for autoimmune and neurodegenerative disorders M Riazifar, MR Mohammadi, EJ Pone, A Yeri, C Lasser, AI Segaliny, ... ACS nano 13 (6), 6670-6688, 2019 | 411 | 2019 |
BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-κB pathway EJ Pone, J Zhang, T Mai, CA White, G Li, JK Sakakura, PJ Patel, ... Nature communications 3 (1), 1-12, 2012 | 315 | 2012 |
Stem cell extracellular vesicles: extended messages of regeneration M Riazifar, EJ Pone, J Lötvall, W Zhao Annual Review of Pharmacology and Toxicology 57, 125-154, 2017 | 286 | 2017 |
HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation SR Park, H Zan, Z Pal, J Zhang, A Al-Qahtani, EJ Pone, Z Xu, T Mai, ... Nature immunology 10 (5), 540-550, 2009 | 180 | 2009 |
14-3-3 adaptor proteins recruit AID to 5′-AGCT-3′–rich switch regions for class switch recombination Z Xu, Z Fulop, G Wu, EJ Pone, J Zhang, T Mai, LM Thomas, A Al-Qahtani, ... Nature structural & molecular biology 17 (9), 1124-1135, 2010 | 169 | 2010 |
Toll-like receptors and B-cell receptors synergize to induce immunoglobulin class-switch DNA recombination: relevance to microbial antibody responses EJ Pone, H Zan, JS Zhang, A Al-Qahtani, Z Xu, P Casali Critical Reviews™ in Immunology 30 (1), 2010 | 166 | 2010 |
Regulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombination Z Xu, EJ Pone, A Al-Qahtani, SR Park, H Zan, P Casali Critical Reviews™ in Immunology 27 (4), 2007 | 144 | 2007 |
Droplet microfluidics for single-molecule and single-cell analysis in cancer research, diagnosis and therapy DK Kang, MM Ali, K Zhang, EJ Pone, W Zhao TrAC Trends in Analytical Chemistry 58, 145-153, 2014 | 134 | 2014 |
Histone deacetylase inhibitors upregulate B cell microRNAs that silence AID and Blimp-1 expression for epigenetic modulation of antibody and autoantibody responses CA White, EJ Pone, T Lam, C Tat, KL Hayama, G Li, H Zan, P Casali The Journal of Immunology 193 (12), 5933-5950, 2014 | 111 | 2014 |
Mechanoresponsive stem cells to target cancer metastases through biophysical cues L Liu, SX Zhang, W Liao, HP Farhoodi, CW Wong, CC Chen, AI Ségaliny, ... Science translational medicine 9 (400), eaan2966, 2017 | 105 | 2017 |
Meteorin-like/Meteorin-β is a novel immunoregulatory cytokine associated with inflammation I Ushach, G Arrevillaga-Boni, GN Heller, E Pone, M Hernandez-Ruiz, ... The Journal of Immunology 201 (12), 3669-3676, 2018 | 89 | 2018 |
Mesenchymal stem cells engineered to express selectin ligands and IL-10 exert enhanced therapeutic efficacy in murine experimental autoimmune encephalomyelitis W Liao, V Pham, L Liu, M Riazifar, EJ Pone, SX Zhang, F Ma, M Lu, ... Biomaterials 77, 87-97, 2016 | 86 | 2016 |
B cell Toll-like receptors and immunoglobulin class-switch DNA recombination EJ Pone, Z Xu, CA White, H Zan, P Casali Frontiers in bioscience (Landmark edition) 17, 2594, 2012 | 72 | 2012 |
B cell TLR1/2, TLR4, TLR7 and TLR9 interact in induction of class switch DNA recombination: modulation by BCR and CD40, and relevance to T-independent antibody responses EJ Pone, Z Lou, T Lam, ML Greenberg, R Wang, Z Xu, P Casali Autoimmunity 48 (1), 1-12, 2015 | 66 | 2015 |
Combinatorial H3K9acS10ph histone modification in IgH locus S regions targets 14-3-3 adaptors and AID to specify antibody class-switch DNA recombination G Li, CA White, T Lam, EJ Pone, DC Tran, KL Hayama, H Zan, Z Xu, ... Cell reports 5 (3), 702-714, 2013 | 55 | 2013 |
DNA‐Scaffolded Multivalent Ligands to Modulate Cell Function Z Zhang, MA Eckert, MM Ali, L Liu, DK Kang, E Chang, EJ Pone, ... ChemBioChem 15 (9), 1268-1273, 2014 | 51 | 2014 |
AID dysregulation in lupus-prone MRL/Fas lpr/lpr mice increases class switch DNA recombination and promotes interchromosomal c-Myc/IgH loci translocations: modulation by HoxC4 CA White, J Seth Hawkins, EJ Pone, ES Yu, A Al-Qahtani, T Mai, H Zan, ... Autoimmunity 44 (8), 585-598, 2011 | 40 | 2011 |
Identification of IL-40, a Novel B Cell–Associated Cytokine J Catalan-Dibene, MI Vazquez, SP Nuccio, A Karimzadeh, ... The Journal of Immunology 199 (9), 3326-3335, 2017 | 39 | 2017 |