Mapping the human genetic architecture of COVID-19 Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ... Nature 600 (7889), 472-477, 2021 | 741 | 2021 |
Parkin‐independent mitophagy requires D rp1 and maintains the integrity of mammalian heart and brain Y Kageyama, M Hoshijima, K Seo, D Bedja, P Sysa‐Shah, SA Andrabi, ... The EMBO journal 33 (23), 2798-2813, 2014 | 429 | 2014 |
In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue S Nishimura, I Manabe, M Nagasaki, K Seo, H Yamashita, Y Hosoya, ... The Journal of clinical investigation 118 (2), 710-721, 2008 | 343 | 2008 |
Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy K Seo, PP Rainer, V Shalkey Hahn, D Lee, SH Jo, A Andersen, T Liu, ... Proceedings of the National Academy of Sciences 111 (4), 1551-1556, 2014 | 208 | 2014 |
Neonatal transplantation confers maturation of PSC-derived cardiomyocytes conducive to modeling cardiomyopathy GS Cho, DI Lee, E Tampakakis, S Murphy, P Andersen, H Uosaki, ... Cell reports 18 (2), 571-582, 2017 | 106 | 2017 |
Hyperactive adverse mechanical stress responses in dystrophic heart are coupled to transient receptor potential canonical 6 and blocked by cGMP–protein kinase G modulation K Seo, PP Rainer, D Lee, S Hao, D Bedja, L Birnbaumer, OH Cingolani, ... Circulation research 114 (5), 823-832, 2014 | 95 | 2014 |
Thrombospondin-4 is required for stretch-mediated contractility augmentation in cardiac muscle OH Cingolani, JA Kirk, K Seo, N Koitabashi, D Lee, G Ramirez-Correa, ... Circulation research 109 (12), 1410-1414, 2011 | 90 | 2011 |
PDE5 inhibitor efficacy is estrogen dependent in female heart disease H Sasaki, T Nagayama, RM Blanton, K Seo, M Zhang, G Zhu, DI Lee, ... The Journal of clinical investigation 124 (6), 2464-2471, 2014 | 80 | 2014 |
Identification of chemicals inducing cardiomyocyte proliferation in developmental stage–specific manner with pluripotent stem cells H Uosaki, A Magadum, K Seo, H Fukushima, A Takeuchi, Y Nakagawa, ... Circulation: Cardiovascular Genetics 6 (6), 624-633, 2013 | 67 | 2013 |
Calcium phosphate microcrystals in the renal tubular fluid accelerate chronic kidney disease progression K Shiizaki, A Tsubouchi, Y Miura, K Seo, T Kuchimaru, H Hayashi, ... The Journal of clinical investigation 131 (16), 2021 | 62 | 2021 |
Selective expansion of regulatory T cells using an orthogonal IL-2/IL-2 receptor system facilitates transplantation tolerance T Hirai, TL Ramos, PY Lin, F Simonetta, LL Su, LK Picton, J Baker, JX Lin, ... The Journal of clinical investigation 131 (8), 2021 | 58 | 2021 |
Responses of single-ventricular myocytes to dynamic axial stretching S Nishimura, K Seo, M Nagasaki, Y Hosoya, H Yamashita, H Fujita, ... Progress in biophysics and molecular biology 97 (2-3), 282-297, 2008 | 56 | 2008 |
Structural heterogeneity in the ventricular wall plays a significant role in the initiation of stretch-induced arrhythmias in perfused rabbit right ventricular tissues and … K Seo, M Inagaki, S Nishimura, I Hidaka, M Sugimachi, T Hisada, ... Circulation research 106 (1), 176-184, 2010 | 54 | 2010 |
Apelin and APJ orchestrate complex tissue-specific control of cardiomyocyte hypertrophy and contractility in the hypertrophy-heart failure transition VN Parikh, J Liu, C Shang, C Woods, AC Chang, M Zhao, DN Charo, ... American Journal of Physiology-Heart and Circulatory Physiology 315 (2 …, 2018 | 44 | 2018 |
Stretch-induced biased signaling in angiotensin II type 1 and apelin receptors for the mediation of cardiac contractility and hypertrophy K Seo, VN Parikh, EA Ashley Frontiers in physiology 11, 181, 2020 | 33 | 2020 |
Allele-specific silencing ameliorates restrictive cardiomyopathy attributable to a human myosin regulatory light chain mutation K Zaleta-Rivera, A Dainis, AJS Ribeiro, P Cordero, G Rubio, C Shang, ... Circulation 140 (9), 765-778, 2019 | 31 | 2019 |
Classifying drugs by their arrhythmogenic risk using machine learning F Sahli-Costabal, K Seo, E Ashley, E Kuhl Biophysical journal 118 (5), 1165-1176, 2020 | 28 | 2020 |
Mono-and biallelic protein-truncating variants in alpha-actinin 2 cause cardiomyopathy through distinct mechanisms ME Lindholm, D Jimenez-Morales, H Zhu, K Seo, D Amar, C Zhao, A Raja, ... Circulation: Genomic and Precision Medicine 14 (6), e003419, 2021 | 14 | 2021 |
High-throughput SARS-CoV-2 and host genome sequencing from single nasopharyngeal swabs JE Gorzynski, HN De Jong, D Amar, C Hughes, A Ioannidis, R Bierman, ... medRxiv, 2020.07. 27.20163147, 2020 | 13 | 2020 |
Relevance of cardiomyocyte mechano-electric coupling to stretch-induced arrhythmias: optical voltage/calcium measurement in mechanically stimulated cells, tissues and organs K Seo, M Inagaki, I Hidaka, H Fukano, M Sugimachi, T Hisada, ... Progress in Biophysics and Molecular Biology 115 (2-3), 129-139, 2014 | 12 | 2014 |