Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling AS Zannas, J Arloth, T Carrillo-Roa, S Iurato, S Röh, KJ Ressler, ... Genome biology 16, 1-12, 2015 | 430 | 2015 |
The role of m6A/m-RNA methylation in stress response regulation M Engel, C Eggert, PM Kaplick, M Eder, S Röh, L Tietze, C Namendorf, ... Neuron 99 (2), 389-403. e9, 2018 | 361 | 2018 |
Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB–driven inflammation and cardiovascular risk AS Zannas, M Jia, K Hafner, J Baumert, T Wiechmann, JC Pape, J Arloth, ... Proceedings of the National Academy of Sciences 116 (23), 11370-11379, 2019 | 232 | 2019 |
Dexamethasone stimulated gene expression in peripheral blood is a sensitive marker for glucocorticoid receptor resistance in depressed patients A Menke, J Arloth, B Pütz, P Weber, T Klengel, D Mehta, M Gonik, ... Neuropsychopharmacology 37 (6), 1455-1464, 2012 | 204 | 2012 |
Dissecting the association between inflammation, metabolic dysregulation, and specific depressive symptoms: a genetic correlation and 2-sample mendelian randomization study N Kappelmann, J Arloth, MK Georgakis, D Czamara, N Rost, S Ligthart, ... JAMA psychiatry 78 (2), 161-170, 2021 | 183 | 2021 |
Glucocorticoid exposure during hippocampal neurogenesis primes future stress response by inducing changes in DNA methylation N Provençal, J Arloth, A Cattaneo, C Anacker, N Cattane, T Wiechmann, ... Proceedings of the National Academy of Sciences 117 (38), 23280-23285, 2020 | 172 | 2020 |
Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation TFM Andlauer, D Buck, G Antony, A Bayas, L Bechmann, A Berthele, ... Science advances 2 (6), e1501678, 2016 | 149 | 2016 |
An adverse early life environment can enhance stress resilience in adulthood S Santarelli, C Zimmermann, G Kalideris, SL Lesuis, J Arloth, A Uribe, ... Psychoneuroendocrinology 78, 213-221, 2017 | 137 | 2017 |
Genetic differences in the immediate transcriptome response to stress predict risk-related brain function and psychiatric disorders J Arloth, R Bogdan, P Weber, G Frishman, A Menke, KV Wagner, ... Neuron 86 (5), 1189-1202, 2015 | 123 | 2015 |
Re-annotator: annotation pipeline for microarray probe sequences J Arloth, DM Bader, S Röh, A Altmann PloS one 10 (10), e0139516, 2015 | 106 | 2015 |
An analysis of gene expression in PTSD implicates genes involved in the glucocorticoid receptor pathway and neural responses to stress MW Logue, AK Smith, C Baldwin, EJ Wolf, G Guffanti, A Ratanatharathorn, ... Psychoneuroendocrinology 57, 1-13, 2015 | 92 | 2015 |
Impact on birth weight of maternal smoking throughout pregnancy mediated by DNA methylation SH Witt, J Frank, M Gilles, M Lang, J Treutlein, F Streit, IAC Wolf, V Peus, ... Bmc Genomics 19, 1-10, 2018 | 69 | 2018 |
Identification of dynamic glucocorticoid-induced methylation changes at the FKBP5 locus T Wiechmann, S Röh, S Sauer, D Czamara, J Arloth, M Ködel, M Beintner, ... Clinical Epigenetics 11, 1-14, 2019 | 64 | 2019 |
DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning J Arloth, G Eraslan, TFM Andlauer, J Martins, S Iurato, B Kühnel, ... PLoS computational biology 16 (2), e1007616, 2020 | 60 | 2020 |
The brain’s hemodynamic response function rapidly changes under acute psychosocial stress in association with genetic and endocrine stress response markers IG Elbau, B Brücklmeier, M Uhr, J Arloth, D Czamara, VI Spoormaker, ... Proceedings of the National Academy of Sciences 115 (43), E10206-E10215, 2018 | 59 | 2018 |
Anxiety associated increased CpG methylation in the promoter of Asb1: a translational approach evidenced by epidemiological and clinical studies and a murine model RT Emeny, J Baumert, AS Zannas, S Kunze, S Wahl, S Iurato, J Arloth, ... Neuropsychopharmacology 43 (2), 342-353, 2018 | 50 | 2018 |
DNA methylation signatures in panic disorder S Iurato, T Carrillo-Roa, J Arloth, D Czamara, L Diener-Hölzl, J Lange, ... Translational psychiatry 7 (12), 1287, 2017 | 50 | 2017 |
Cell-type-specific impact of glucocorticoid receptor activation on the developing brain: a cerebral organoid study C Cruceanu, L Dony, AC Krontira, DS Fischer, S Roeh, R Di Giaimo, ... American Journal of Psychiatry 179 (5), 375-387, 2022 | 46 | 2022 |
Dexamethasone stimulated gene expression in peripheral blood indicates glucocorticoid-receptor hypersensitivity in job-related exhaustion A Menke, J Arloth, M Gerber, M Rex-Haffner, M Uhr, F Holsboer, ... Psychoneuroendocrinology 44, 35-46, 2014 | 46 | 2014 |
Polygenic risk for immuno-metabolic markers and specific depressive symptoms: A multi-sample network analysis study N Kappelmann, D Czamara, N Rost, S Moser, V Schmoll, L Trastulla, ... Brain, Behavior, and Immunity 95, 256-268, 2021 | 45 | 2021 |