Involvement of distinct arrestin-1 elements in binding to different functional forms of rhodopsin T Zhuang, Q Chen, MK Cho, SA Vishnivetskiy, TM Iverson, VV Gurevich, ... Proceedings of the National Academy of Sciences 110 (3), 942-947, 2013 | 123 | 2013 |
Structural basis of arrestin-3 activation and signaling Q Chen, NA Perry, SA Vishnivetskiy, S Berndt, NC Gilbert, Y Zhuo, ... Nature Communications 8 (1), 1427, 2017 | 120 | 2017 |
Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1 Q Chen, M Plasencia, Z Li, S Mukherjee, D Patra, CL Chen, T Klose, ... Nature 595 (7868), 600-605, 2021 | 104 | 2021 |
Structural basis of arrestin-dependent signal transduction Q Chen, TM Iverson, VV Gurevich Trends in biochemical sciences 43 (6), 412-423, 2018 | 82 | 2018 |
Peptide mini-scaffold facilitates JNK3 activation in cells X Zhan, H Stoy, TS Kaoud, NA Perry, Q Chen, A Perez, S Els-Heindl, ... Scientific Reports 6 (1), 21025, 2016 | 63 | 2016 |
Engineering visual arrestin-1 with special functional characteristics SA Vishnivetskiy, Q Chen, MC Palazzo, EK Brooks, C Altenbach, ... Journal of Biological Chemistry 288 (5), 3394-3405, 2013 | 49 | 2013 |
Arrestin-3 scaffolding of the JNK3 cascade suggests a mechanism for signal amplification NA Perry, TS Kaoud, OO Ortega, AI Kaya, DJ Marcus, JM Pleinis, S Berndt, ... Proceedings of the National Academy of Sciences 116 (3), 810-815, 2019 | 47 | 2019 |
Using two-site binding models to analyze microscale thermophoresis data SC Tso, Q Chen, SA Vishnivetskiy, VV Gurevich, TM Iverson, ... Analytical biochemistry 540, 64-75, 2018 | 42 | 2018 |
G protein–coupled receptor interactions with arrestins and GPCR kinases: The unresolved issue of signal bias Q Chen, JJG Tesmer Journal of Biological Chemistry 298 (9), 2022 | 35 | 2022 |
Self-association of arrestin family members Q Chen, Y Zhuo, M Kim, SM Hanson, DJ Francis, SA Vishnivetskiy, ... Arrestins-Pharmacology and Therapeutic Potential, 205-223, 2014 | 35 | 2014 |
Rapid degeneration of rod photoreceptors expressing self-association-deficient arrestin-1 mutant X Song, J Seo, F Baameur, SA Vishnivetskiy, Q Chen, S Kook, M Kim, ... Cellular signalling 25 (12), 2613-2624, 2013 | 29 | 2013 |
Arrestin Expression in E. coli and Purification SA Vishnivetskiy, X Zhan, Q Chen, TM Iverson, VV Gurevich Current Protocols in Pharmacology 67 (1), 2.11. 1-2.11. 19, 2014 | 25 | 2014 |
Perturbation of the interactions of calmodulin with GRK5 using a natural product chemical probe TS Beyett, AE Fraley, E Labudde, D Patra, RC Coleman, A Eguchi, ... Proceedings of the National Academy of Sciences 116 (32), 15895-15900, 2019 | 23 | 2019 |
An eight amino acid segment controls oligomerization and preferred conformation of the two non-visual arrestins Q Chen, Y Zhuo, P Sharma, I Perez, DJ Francis, S Chakravarthy, ... Journal of molecular biology 433 (4), 166790, 2021 | 20 | 2021 |
Structure-based design of selective, covalent G protein-coupled receptor kinase 5 inhibitors RA Rowlands, MC Cato, HV Waldschmidt, RA Bouley, Q Chen, ... ACS Medicinal Chemistry Letters 10 (12), 1628-1634, 2019 | 14 | 2019 |
A receptor on acid Q Chen, JJG Tesmer Cell 168 (3), 339-341, 2017 | 13 | 2017 |
ACKR3–arrestin2/3 complexes reveal molecular consequences of GRK-dependent barcoding Q Chen, CT Schafer, S Mukherjee, M Gustavsson, P Agrawal, XQ Yao, ... bioRxiv, 2023 | 11 | 2023 |
Atypical Chemokine Receptor 3 “Senses” CXC Chemokine Receptor 4 Activation Through GPCR Kinase Phosphorylation CT Schafer, Q Chen, JJG Tesmer, TM Handel Molecular Pharmacology 104 (4), 174-186, 2023 | 10 | 2023 |
Short arrestin-3-derived peptides activate JNK3 in cells NA Perry-Hauser, TS Kaoud, H Stoy, X Zhan, Q Chen, KN Dalby, ... International Journal of Molecular Sciences 23 (15), 8679, 2022 | 10 | 2022 |
Generation of highly selective, potent, and covalent G protein-coupled receptor kinase 5 inhibitors RA Rowlands, Q Chen, RA Bouley, LV Avramova, JJG Tesmer, AD White Journal of medicinal chemistry 64 (1), 566-585, 2021 | 10 | 2021 |