Increased expression of the dopamine transporter leads to loss of dopamine neurons, oxidative stress and l-DOPA reversible motor deficits ST Masoud, LM Vecchio, Y Bergeron, MM Hossain, LT Nguyen, ... Neurobiology of disease 74, 66-75, 2015 | 170 | 2015 |
Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson’s disease D Jennings, S Huntwork-Rodriguez, AG Henry, JC Sasaki, R Meisner, ... Science translational medicine 14 (648), eabj2658, 2022 | 161 | 2022 |
Membrane transporters as mediators of synaptic dopamine dynamics: implications for disease KM Lohr, ST Masoud, A Salahpour, GW Miller European Journal of Neuroscience 45 (1), 20-33, 2017 | 128 | 2017 |
Misassembly of full-length Disrupted-in-Schizophrenia 1 protein is linked to altered dopamine homeostasis and behavioral deficits SV Trossbach, V Bader, L Hecher, ME Pum, ST Masoud, I Prikulis, ... Molecular psychiatry 21 (11), 1561-1572, 2016 | 96 | 2016 |
The cost-effectiveness of palivizumab for respiratory syncytial virus prophylaxis in premature infants with a gestational age of 32–35 weeks: a Canadian-based analysis KL Lanctôt, ST Masoud, BA Paes, JE Tarride, A Chiu, C Hui, PL Francis, ... Current medical research and opinion 24 (11), 3223-3237, 2008 | 78 | 2008 |
D1 dopamine receptor coupling to PLCβ regulates forward locomotion in mice IO Medvedev, AJ Ramsey, ST Masoud, MK Bermejo, N Urs, TD Sotnikova, ... Journal of Neuroscience 33 (46), 18125-18133, 2013 | 76 | 2013 |
Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia D Xia, S Lianoglou, T Sandmann, M Calvert, JH Suh, E Thomsen, ... Molecular neurodegeneration 17 (1), 41, 2022 | 70 | 2022 |
Comparison of the cost of hospitalization for respiratory syncytial virus disease versus palivizumab prophylaxis in Canadian Inuit infants A Banerji, KL Lanctôt, BA Paes, ST Masoud, DY Tam, WA Macdonald, ... The Pediatric infectious disease journal 28 (8), 702-706, 2009 | 64 | 2009 |
Enhanced tyrosine hydroxylase activity induces oxidative stress, causes accumulation of autotoxic catecholamine metabolites, and augments amphetamine effects in vivo LM Vecchio, P Sullivan, AR Dunn, MK Bermejo, R Fu, ST Masoud, ... Journal of neurochemistry 158 (4), 960-979, 2021 | 31 | 2021 |
Assessing the validity of deriving clinical dementia rating (CDR) global scores from independently-obtained functional rating scale (FRS) scores in vascular dementia with and … KL Lanctôt, GYR Hsiung, HH Feldman, ST Masoud, L Sham, N Herrmann International journal of geriatric psychiatry 24 (10), 2009 | 10 | 2009 |
Fibrillar Aβ causes profound microglial metabolic perturbations in a novel APP knock-in mouse model D Xia, S Lianoglou, T Sandmann, M Calvert, JH Suh, E Thomsen, ... bioRxiv, 2021.01. 19.426731, 2021 | 8 | 2021 |
LRRK2 Kinase Activity Regulates Parkinson’s Disease-Relevant Lipids at the Lysosome MT Maloney, X Wang, R Ghosh, SV Andrews, R Maciuca, ST Masoud, ... bioRxiv, 2022.12. 19.521070, 2022 | 3 | 2022 |
ETV: SGSH, a brain-penetrant enzyme transport vehicle for SGSH, improves lysosomal and microglial morphology, degeneration and cognitive behavior in MPS IIIA mice ST Masoud, H Nguyen, C Discenza, D Joy, J Simms, I Lo, YY Chun, ... Molecular Genetics and Metabolism 141 (2), 107954, 2024 | | 2024 |
ETV: SGSH, a brain-penetrant enzyme transport vehicle for SGSH, corrects heparan sulfate accumulation, lysosomal lipid storage and inflammation in MPS IIIA mouse brain ST Masoud, M Jafarnejad, H Nguyen, B Tsogtbaatar, Y Rajendra, A Seay, ... Molecular Genetics and Metabolism 138 (2), 107223, 2023 | | 2023 |
Characterization of Mice with Altered Dopamine Transporter and Vesicular Monoamine Transporter 2 Levels ST Masoud University of Toronto (Canada), 2017 | | 2017 |