Paradigm Shift for Radical S-Adenosyl-l-methionine Reactions: The Organometallic Intermediate Ω Is Central to Catalysis AS Byer, H Yang, EC McDaniel, V Kathiresan, S Impano, A Pagnier, ... Journal of the American Chemical Society 140 (28), 8634-8638, 2018 | 93 | 2018 |
The elusive 5′-deoxyadenosyl radical: captured and characterized by electron paramagnetic resonance and electron nuclear double resonance spectroscopies H Yang, EC McDaniel, S Impano, AS Byer, RJ Jodts, K Yokoyama, ... Journal of the American Chemical Society 141 (30), 12139-12146, 2019 | 83 | 2019 |
Photoinduced Electron Transfer in a Radical SAM Enzyme Generates an S-Adenosylmethionine Derived Methyl Radical H Yang, S Impano, EM Shepard, CD James, WE Broderick, JB Broderick, ... Journal of the American Chemical Society 141 (40), 16117-16124, 2019 | 40 | 2019 |
Mechanistic studies of radical SAM enzymes: pyruvate Formate-Lyase activating enzyme and lysine 2, 3-Aminomutase case studies AS Byer, EC McDaniel, S Impano, WE Broderick, JB Broderick Methods in enzymology 606, 269-318, 2018 | 24 | 2018 |
S‐Adenosyl‐l‐ethionine is a Catalytically Competent Analog of S‐Adenosyl‐l‐methionine (SAM) in the Radical SAM Enzyme HydG S Impano, H Yang, EM Shepard, R Swimley, A Pagnier, WE Broderick, ... Angewandte Chemie 133 (9), 4716-4722, 2021 | 22 | 2021 |
Active-Site Controlled, Jahn–Teller Enabled Regioselectivity in Reductive S–C Bond Cleavage of S-Adenosylmethionine in Radical SAM Enzymes S Impano, H Yang, RJ Jodts, A Pagnier, R Swimley, EC McDaniel, ... Journal of the American Chemical Society 143 (1), 335-348, 2020 | 20 | 2020 |
[FeFe]‐Hydrogenase: Defined Lysate‐Free Maturation Reveals a Key Role for Lipoyl‐H‐Protein in DTMA Ligand Biosynthesis A Pagnier, B Balci, EM Shepard, H Yang, DM Warui, S Impano, SJ Booker, ... Angewandte Chemie International Edition 61 (22), e202203413, 2022 | 19 | 2022 |
Radical SAM enzyme spore photoproduct lyase: properties of the Ω organometallic intermediate and identification of stable protein radicals formed during substrate-free turnover A Pagnier, H Yang, RJ Jodts, CD James, EM Shepard, S Impano, ... Journal of the American Chemical Society 142 (43), 18652-18660, 2020 | 13 | 2020 |
HydG, the “dangler” iron, and catalytic production of free CO and CN−: implications for [FeFe]-hydrogenase maturation EM Shepard, S Impano, BR Duffus, A Pagnier, KS Duschene, JN Betz, ... Dalton Transactions 50 (30), 10405-10422, 2021 | 10 | 2021 |
Cover Picture:[FeFe]‐Hydrogenase: Defined Lysate‐Free Maturation Reveals a Key Role for Lipoyl‐H‐Protein in DTMA Ligand Biosynthesis (Angew. Chem. Int. Ed. 22/2022) A Pagnier, B Balci, EM Shepard, H Yang, DM Warui, S Impano, SJ Booker, ... Angewandte Chemie International Edition 61 (22), e202204929, 2022 | | 2022 |
New Insights into Radical Initiation by Radical S-Adenosylmethionine Enzymes and Activation of [FeFe]-Hydrogenase S Impano Montana State University, 2020 | | 2020 |
Probing a Possible Cation Binding Site in [FeFe]-hydrogenase maturation enzyme, HydE S Impano, E Shepard, J Betz, A Pagnier, W Broderick, J Broderick ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019 | | 2019 |