关注
Sourav Saha
Sourav Saha
Research Fellow, NCI, NIH
在 nih.gov 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Excision repair of topoisomerase DNA-protein crosslinks (TOP-DPC)
Y Sun*, S Saha*, W Wang, LK Saha, SYN Huang, Y Pommier
DNA repair 89, 102837, 2020
742020
Debulking of topoisomerase DNA-protein crosslinks (TOP-DPC) by the proteasome, non-proteasomal and non-proteolytic pathways
Y Sun, LK Saha, S Saha, U Jo, Y Pommier
DNA repair 94, 102926, 2020
632020
A Novel Spirooxindole Derivative Inhibits the Growth of Leishmania donovani Parasites both In Vitro and In Vivo by Targeting Type IB Topoisomerase
S Saha, C Acharya, U Pal, SR Chowdhury, K Sarkar, NC Maiti, ...
Antimicrobial agents and chemotherapy 60 (10), 6281-6293, 2016
582016
Voacamine alters Leishmania ultrastructure and kills parasite by poisoning unusual bi-subunit topoisomerase IB
SR Chowdhury, A Kumar, JLP Godinho, STDM Silva, AA Zuma, S Saha, ...
Biochemical pharmacology 138, 19-30, 2017
382017
PARylation prevents the proteasomal degradation of topoisomerase I DNA-protein crosslinks and induces their deubiquitylation
Y Sun, J Chen, SN Huang, YP Su, W Wang, K Agama, S Saha, ...
Nature Communications 12 (1), 5010, 2021
342021
DNA and RNA Cleavage Complexes and Repair Pathway for TOP3B RNA-and DNA-Protein Crosslinks
S Saha, Y Sun, SN Huang, SA Baechler, LS Pongor, K Agama, U Jo, ...
Cell Reports 33 (13), 108569, 2020
34*2020
The lignan glycosides lyoniside and saracoside poison the unusual type IB topoisomerase of Leishmania donovani and kill the parasite both in vitro and in vivo
S Saha, T Mukherjee, S Chowdhury, A Mishra, SR Chowdhury, ...
Biochemical pharmacology 86 (12), 1673-1687, 2013
342013
Synthesis and biological evaluation of calothrixins B and their deoxygenated analogs
BM Ramalingam, ND Moorthy, SR Chowdhury, T Mageshwaran, ...
J. Med. Chem 61, 1285-1315, 2018
292018
Replication-dependent cytotoxicity and Spartan-mediated repair of trapped PARP1–DNA complexes
LK Saha, Y Murai, S Saha, U Jo, M Tsuda, S Takeda, Y Pommier
Nucleic Acids Research 49 (18), 10493-10506, 2021
262021
Synthesis and structure-activity relationship of furoquinolinediones as inhibitors of Tyrosyl-DNA phosphodiesterase 2 (TDP2)
LM Yu, Z Hu, Y Chen, A Ravji, S Lopez, CB Plescia, Q Yu, H Yang, ...
European journal of medicinal chemistry 151, 777-796, 2018
222018
Resolution of R-loops by topoisomerase III-β (TOP3B) in coordination with the DEAD-box helicase DDX5
S Saha, X Yang, SN Huang, K Agama, SA Baechler, Y Sun, H Zhang, ...
Cell Reports 40 (2), 111067, 2022
212022
Isobenzofuranone derivatives exhibit antileishmanial effect by inhibiting type II DNA topoisomerase and inducing host response
A Mishra, J Vinayagam, S Saha, S Chowdhury, S Roychowdhury, ...
Pharmacology research & perspectives 2 (6), e00070, 2014
202014
DNA topoisomerases of kinetoplastid parasites: brief overview and recent perspectives
S Saha, SR Chowdhury, HK Majumder
Current issues in molecular biology 31 (1), 45-62, 2019
102019
Replication-associated formation and repair of human topoisomerase IIIα cleavage complexes
LK Saha, S Saha, X Yang, SN Huang, Y Sun, U Jo, Y Pommier
Nature Communications 14 (1), 1925, 2023
82023
R-loops, type I topoisomerases and cancer
S Saha, Y Pommier
NAR Cancer 5 (1), zcad013, 2023
82023
Flavone-resistant Leishmania donovani overexpresses LdMRP2 transporter in the parasite and activates host MRP2 on macrophages to circumvent the flavone-mediated cell death
S Chowdhury, R Mukhopadhyay, S Saha, A Mishra, S Sengupta, S Roy, ...
Journal of Biological Chemistry 289 (23), 16129-16147, 2014
82014
Structural and biochemical basis for DNA and RNA catalysis by human Topoisomerase 3β
X Yang, S Saha, W Yang, KC Neuman, Y Pommier
Nature Communications 13 (1), 4656, 2022
52022
Identification and characterization of topoisomerase III beta poisons
W Wang*, S Saha*, X Yang, Y Pommier, SN Huang
Proceedings of the National Academy of Sciences (PNAS) 120 (34), e2218483120, 2023
22023
The TDRD3-USP9X complex and MIB1 regulate TOP3B homeostasis and prevent deleterious TOP3B cleavage complexes
S Saha, SN Huang, X Yang, LK Saha, Y Sun, P Khandagale, LM Jenkins, ...
Nature Communications 14 (1), 7524, 2023
12023
Flap endonuclease 1 repairs DNA-protein crosslinks via ADP-ribosylation
Y Sun, LM Jenkins, LH El Touny, U Jo, X Yang, TK Maity, I Uribe, S Saha, ...
bioRxiv, 2023.10. 19.563118, 2023
2023
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