Excision repair of topoisomerase DNA-protein crosslinks (TOP-DPC) Y Sun*, S Saha*, W Wang, LK Saha, SYN Huang, Y Pommier DNA repair 89, 102837, 2020 | 74 | 2020 |
Debulking of topoisomerase DNA-protein crosslinks (TOP-DPC) by the proteasome, non-proteasomal and non-proteolytic pathways Y Sun, LK Saha, S Saha, U Jo, Y Pommier DNA repair 94, 102926, 2020 | 63 | 2020 |
A Novel Spirooxindole Derivative Inhibits the Growth of Leishmania donovani Parasites both In Vitro and In Vivo by Targeting Type IB Topoisomerase S Saha, C Acharya, U Pal, SR Chowdhury, K Sarkar, NC Maiti, ... Antimicrobial agents and chemotherapy 60 (10), 6281-6293, 2016 | 58 | 2016 |
Voacamine alters Leishmania ultrastructure and kills parasite by poisoning unusual bi-subunit topoisomerase IB SR Chowdhury, A Kumar, JLP Godinho, STDM Silva, AA Zuma, S Saha, ... Biochemical pharmacology 138, 19-30, 2017 | 38 | 2017 |
PARylation prevents the proteasomal degradation of topoisomerase I DNA-protein crosslinks and induces their deubiquitylation Y Sun, J Chen, SN Huang, YP Su, W Wang, K Agama, S Saha, ... Nature Communications 12 (1), 5010, 2021 | 34 | 2021 |
DNA and RNA Cleavage Complexes and Repair Pathway for TOP3B RNA-and DNA-Protein Crosslinks S Saha, Y Sun, SN Huang, SA Baechler, LS Pongor, K Agama, U Jo, ... Cell Reports 33 (13), 108569, 2020 | 34* | 2020 |
The lignan glycosides lyoniside and saracoside poison the unusual type IB topoisomerase of Leishmania donovani and kill the parasite both in vitro and in vivo S Saha, T Mukherjee, S Chowdhury, A Mishra, SR Chowdhury, ... Biochemical pharmacology 86 (12), 1673-1687, 2013 | 34 | 2013 |
Synthesis and biological evaluation of calothrixins B and their deoxygenated analogs BM Ramalingam, ND Moorthy, SR Chowdhury, T Mageshwaran, ... J. Med. Chem 61, 1285-1315, 2018 | 29 | 2018 |
Replication-dependent cytotoxicity and Spartan-mediated repair of trapped PARP1–DNA complexes LK Saha, Y Murai, S Saha, U Jo, M Tsuda, S Takeda, Y Pommier Nucleic Acids Research 49 (18), 10493-10506, 2021 | 26 | 2021 |
Synthesis and structure-activity relationship of furoquinolinediones as inhibitors of Tyrosyl-DNA phosphodiesterase 2 (TDP2) LM Yu, Z Hu, Y Chen, A Ravji, S Lopez, CB Plescia, Q Yu, H Yang, ... European journal of medicinal chemistry 151, 777-796, 2018 | 22 | 2018 |
Resolution of R-loops by topoisomerase III-β (TOP3B) in coordination with the DEAD-box helicase DDX5 S Saha, X Yang, SN Huang, K Agama, SA Baechler, Y Sun, H Zhang, ... Cell Reports 40 (2), 111067, 2022 | 21 | 2022 |
Isobenzofuranone derivatives exhibit antileishmanial effect by inhibiting type II DNA topoisomerase and inducing host response A Mishra, J Vinayagam, S Saha, S Chowdhury, S Roychowdhury, ... Pharmacology research & perspectives 2 (6), e00070, 2014 | 20 | 2014 |
DNA topoisomerases of kinetoplastid parasites: brief overview and recent perspectives S Saha, SR Chowdhury, HK Majumder Current issues in molecular biology 31 (1), 45-62, 2019 | 10 | 2019 |
Replication-associated formation and repair of human topoisomerase IIIα cleavage complexes LK Saha, S Saha, X Yang, SN Huang, Y Sun, U Jo, Y Pommier Nature Communications 14 (1), 1925, 2023 | 8 | 2023 |
R-loops, type I topoisomerases and cancer S Saha, Y Pommier NAR Cancer 5 (1), zcad013, 2023 | 8 | 2023 |
Flavone-resistant Leishmania donovani overexpresses LdMRP2 transporter in the parasite and activates host MRP2 on macrophages to circumvent the flavone-mediated cell death S Chowdhury, R Mukhopadhyay, S Saha, A Mishra, S Sengupta, S Roy, ... Journal of Biological Chemistry 289 (23), 16129-16147, 2014 | 8 | 2014 |
Structural and biochemical basis for DNA and RNA catalysis by human Topoisomerase 3β X Yang, S Saha, W Yang, KC Neuman, Y Pommier Nature Communications 13 (1), 4656, 2022 | 5 | 2022 |
Identification and characterization of topoisomerase III beta poisons W Wang*, S Saha*, X Yang, Y Pommier, SN Huang Proceedings of the National Academy of Sciences (PNAS) 120 (34), e2218483120, 2023 | 2 | 2023 |
The TDRD3-USP9X complex and MIB1 regulate TOP3B homeostasis and prevent deleterious TOP3B cleavage complexes S Saha, SN Huang, X Yang, LK Saha, Y Sun, P Khandagale, LM Jenkins, ... Nature Communications 14 (1), 7524, 2023 | 1 | 2023 |
Flap endonuclease 1 repairs DNA-protein crosslinks via ADP-ribosylation Y Sun, LM Jenkins, LH El Touny, U Jo, X Yang, TK Maity, I Uribe, S Saha, ... bioRxiv, 2023.10. 19.563118, 2023 | | 2023 |