| iGEMDOCK: a graphical environment of enhancing GEMDOCK using pharmacological interactions and post-screening analysis KC Hsu, YF Chen, SR Lin, JM Yang BMC bioinformatics 12, 1-11, 2011 | 539 | 2011 |
| The role of ubiquitin-specific peptidases in cancer progression MJ Young, KC Hsu, TE Lin, WC Chang, JJ Hung Journal of Biomedical Science 26, 1-14, 2019 | 136 | 2019 |
| KDM4B as a target for prostate cancer: structural analysis and selective inhibition by a novel inhibitor CH Chu, LY Wang, KC Hsu, CC Chen, HH Cheng, SM Wang, CM Wu, ... Journal of medicinal chemistry 57 (14), 5975-5985, 2014 | 106 | 2014 |
| Evaluation of machine learning methods to stroke outcome prediction using a nationwide disease registry CH Lin, KC Hsu, KR Johnson, YC Fann, CH Tsai, YU Sun, LM Lien, ... Computer methods and programs in biomedicine 190, 105381, 2020 | 85 | 2020 |
| Structural Insights into the Cytotoxic Mechanism of Vibrio parahaemolyticus PirAvp and PirBvp Toxins SJ Lin, KC Hsu, HC Wang Marine drugs 15 (12), 373, 2017 | 74 | 2017 |
| 5-Aroylindoles act as selective histone deacetylase 6 inhibitors ameliorating Alzheimer’s disease phenotypes HY Lee, SJ Fan, FI Huang, HY Chao, KC Hsu, TE Lin, TK Yeh, MJ Lai, ... Journal of Medicinal Chemistry 61 (16), 7087-7102, 2018 | 68 | 2018 |
| Crowning proteins: modulating the protein surface properties using crown ethers CC Lee, M Maestre‐Reyna, KC Hsu, HC Wang, CI Liu, WY Jeng, LL Lin, ... Angewandte Chemie 126 (48), 13270-13274, 2014 | 57 | 2014 |
| DNA mimic proteins: functions, structures, and bioinformatic analysis HC Wang, CH Ho, KC Hsu, JM Yang, AHJ Wang Biochemistry 53 (18), 2865-2874, 2014 | 57 | 2014 |
| Dual inhibition of PIK3C3 and FGFR as a new therapeutic approach to treat bladder cancer CH Chen, CA Changou, TH Hsieh, YC Lee, CY Chu, KC Hsu, HC Wang, ... Clinical Cancer Research 24 (5), 1176-1189, 2018 | 56 | 2018 |
| Staphylococcus aureus protein SAUGI acts as a uracil-DNA glycosylase inhibitor HC Wang, KC Hsu, JM Yang, ML Wu, TP Ko, SR Lin, AHJ Wang Nucleic acids research 42 (2), 1354-1364, 2013 | 54 | 2013 |
| Novel Class IIa-Selective Histone Deacetylase Inhibitors Discovered Using an in Silico Virtual Screening Approach KC Hsu, CY Liu, TE Lin, JH Hsieh, TY Sung, HJ Tseng, JM Yang, ... Scientific Reports 7 (1), 3228, 2017 | 51 | 2017 |
| SiMMap: a web server for inferring site-moiety map to recognize interaction preferences between protein pockets and compound moieties YF Chen, KC Hsu, SR Lin, WC Wang, YC Huang, JM Yang Nucleic acids research 38 (suppl_2), W424-W430, 2010 | 47 | 2010 |
| Synthesis and biological evaluation of acridine-based histone deacetylase inhibitors as multitarget agents against Alzheimer’s disease HJ Tseng, MH Lin, YJ Shiao, YC Yang, JC Chu, CY Chen, YY Chen, ... European Journal of Medicinal Chemistry 192, 112193, 2020 | 43 | 2020 |
| Structures of Helicobacter pylori shikimate kinase reveal a selective inhibitor-induced-fit mechanism WC Cheng, YF Chen, HJ Wang, KC Hsu, SC Lin, TJ Chen, JM Yang, ... PLoS One 7 (3), e33481, 2012 | 42 | 2012 |
| Structural Insights to the Heterotetrameric Interaction between the Vibrio parahaemolyticus PirAvp and PirBvp Toxins and Activation of the Cry-Like Pore … SJ Lin, YF Chen, KC Hsu, YL Chen, TP Ko, CF Lo, HC Wang, HC Wang Toxins 11 (4), 233, 2019 | 41 | 2019 |
| 1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase MJ Lai, R Ojha, MH Lin, YM Liu, HY Lee, TE Lin, KC Hsu, CY Chang, ... European journal of medicinal chemistry 162, 612-630, 2019 | 41 | 2019 |
| Serial crystallography captures dynamic control of sequential electron and proton transfer events in a flavoenzyme M Maestre-Reyna, CH Yang, E Nango, WC Huang, EPG Ngurah Putu, ... Nature Chemistry 14 (6), 677-685, 2022 | 40 | 2022 |
| Purine/purine isoster based scaffolds as new derivatives of benzamide class of HDAC inhibitors K Nepali, TY Chang, MJ Lai, KC Hsu, Y Yen, TE Lin, SB Lee, JP Liou European Journal of Medicinal Chemistry 196, 112291, 2020 | 39 | 2020 |
| Isoindoline scaffold-based dual inhibitors of HDAC6 and HSP90 suppressing the growth of lung cancer in vitro and in vivo R Ojha, K Nepali, CH Chen, KH Chuang, TY Wu, TE Lin, KC Hsu, ... European journal of medicinal chemistry 190, 112086, 2020 | 38 | 2020 |
| Synthesis of acylguanidine zanamivir derivatives as neuraminidase inhibitors and the evaluation of their bio-activities CH Lin, TC Chang, A Das, MY Fang, HC Hung, KC Hsu, JM Yang, ... Organic & Biomolecular Chemistry 11 (24), 3943-3948, 2013 | 37 | 2013 |
