| NuMA promotes homologous recombination repair by regulating the accumulation of the ISWI ATPase SNF2h at DNA breaks PA Vidi, J Liu, D Salles, S Jayaraman, G Dorfman, M Gray, P Abad, ... Nucleic acids research 42 (10), 6365-6379, 2014 | 68 | 2014 |
| Functional specialization of domains tandemly duplicated within 16S rRNA methyltransferase RsmC S Sunita, E Purta, M Durawa, KL Tkaczuk, J Swaathi, JM Bujnicki, ... Nucleic acids research 35 (13), 4264-4274, 2007 | 47 | 2007 |
| The nuclear mitotic apparatus protein NuMA controls rDNA transcription and mediates the nucleolar stress response in a p53-independent manner S Jayaraman, S Chittiboyina, Y Bai, PC Abad, PA Vidi, CV Stauffacher, ... Nucleic acids research 45 (20), 11725-11742, 2017 | 39 | 2017 |
| Label-free Raman spectroscopy provides early determination and precise localization of breast cancer-colonized bone alterations C Zhang, PT Winnard Jr, S Dasari, SL Kominsky, M Doucet, S Jayaraman, ... Chemical Science 9 (3), 743-753, 2018 | 31 | 2018 |
| Endoxifen, an estrogen receptor targeted therapy: from bench to bedside S Jayaraman, JM Reid, JR Hawse, MP Goetz Endocrinology 162 (12), bqab191, 2021 | 26 | 2021 |
| CITED2 modulates breast cancer metastatic ability through effects on IKKα S Jayaraman, M Doucet, WM Lau, SL Kominsky Molecular Cancer Research 14 (8), 730-739, 2016 | 26 | 2016 |
| CCL20/CCR6 signaling regulates bone mass accrual in mice M Doucet, S Jayaraman, E Swenson, B Tusing, KL Weber, SL Kominsky Journal of Bone and Mineral Research 31 (7), 1381-1390, 2016 | 26 | 2016 |
| Antitumor activity of Z-endoxifen in aromatase inhibitor-sensitive and aromatase inhibitor-resistant estrogen receptor-positive breast cancer S Jayaraman, X Hou, MJ Kuffel, VJ Suman, TL Hoskin, KE Reinicke, ... Breast Cancer Research 22, 1-12, 2020 | 23 | 2020 |
| Domain organization and crystal structure of the catalytic domain of E. coli RluF, a pseudouridine synthase that acts on 23S rRNA S Sunita, H Zhenxing, J Swaathi, M Cygler, A Matte, J Sivaraman Journal of molecular biology 359 (4), 998-1009, 2006 | 21 | 2006 |
| CITED2 attenuates macrophage recruitment concordant with the downregulation of CCL20 in breast cancer cells S Jayaraman, M Doucet, SL Kominsky Oncology Letters 15 (1), 871-878, 2018 | 20 | 2018 |
| Down-regulation of CITED2 attenuates breast tumor growth, vessel formation and TGF-β-induced expression of VEGFA S Jayaraman, M Doucet, SL Kominsky Oncotarget 8 (4), 6169, 2016 | 14 | 2016 |
| Endoxifen downregulates AKT phosphorylation through protein kinase C beta 1 inhibition in ERα+ breast cancer S Jayaraman, X Wu, KR Kalari, X Tang, MJ Kuffel, ES Bruinsma, S Jalali, ... NPJ Breast Cancer 9 (1), 101, 2023 | 3 | 2023 |
| Abstract LB102: Hexyl-(cuban-1-yl-methyl)-biguanide (HCB) suppresses N-glycosylation of immune checkpoint proteins B7-H3 and B7-H4, reverses tumor hypoxia, decreases … Z Guo, J Lei, H Venkatesh, D Owen, A Bass, C Cannon, J McCarra, ... Cancer Research 83 (8_Supplement), LB102-LB102, 2023 | 1 | 2023 |
| (+/-) 14, 15-epoxyeicosatrienoic acid induces hallmark ER and MYC gene expression and associated ER and c-Myc nuclear translocation in ER+/HER2-breast cancer cells J Lei, Z Guo, J Molina-Vega, P Cervantes, S Jayaraman, JR Hawse, ... Cancer Research 82 (12), 2022 | 1 | 2022 |
| Abstract P6-04-06: Protein kinase C beta 1 (PKCβ1), a novel drug target of Z-endoxifen, inhibits growth of estrogen receptor positive (ER+) breast cancer via activation of the … S Jayaraman, MJ Kuffel, KR Kalari, KJ Thompson, X Tang, ES Bruinsma, ... Cancer Research 80 (4_Supplement), P6-04-06-P6-04-06, 2020 | 1 | 2020 |
| Abstract LB051: Protein kinase C beta 1 (PKCβ1) is allosterically inhibited and paradoxically translocated to the membrane by z-endoxifen SS Bhattacharya, HV Huynh, JK Farmakes, TL Witter, ES Bruinsma, ... Cancer Research 84 (7_Supplement), LB051-LB051, 2024 | | 2024 |
| Abstract LB334: Mechanisms of endocrine resistance to letrozole, fulvestrant, and palbociclib are associated with increased sensitivity to hexyl-cuban-1-yl biguanide inhibitors … Z Guo, J Lei, A Makovec, S Jayaraman, JR Hawse, C Lange, E Ambrose, ... Cancer Research 84 (7_Supplement), LB334-LB334, 2024 | | 2024 |
| Abstract CT205: Neoadjuvant (Z)-endoxifen in premenopausal ER+, HER2-breast cancer: Evaluation of the first pharmacokinetic cohort of the EVANGELINE trial MP Goetz, VJ Suman, H Fraser, L Mina, P Advani, R Leon-Ferre, ... Cancer Research 84 (7_Supplement), CT205-CT205, 2024 | | 2024 |
| Abstract P2-24-03: Z-Endoxifen Allosterically Inhibits PKCβI and its Paradoxical Membrane Translocation SS Bhattacharya, TL Witter, AT Cong, ES Bruinsma, S Jayaraman, ... Cancer Research 83 (5_Supplement), P2-24-03-P2-24-03, 2023 | | 2023 |
| Abstract P3-11-04: Endoxifen Downregulates AKT Phosphorylation Through Protein Kinase C Beta 1 in ER+/HER2-Breast Cancer S Jayaraman, X Wu, KR Kalari, X Tang, M Kuffel, ES Bruinsma, S Renuse, ... Cancer Research 83 (5_Supplement), P3-11-04-P3-11-04, 2023 | | 2023 |
