Ocular surface immunity: homeostatic mechanisms and their disruption in dry eye disease S Barabino, Y Chen, S Chauhan, R Dana Progress in retinal and eye research 31 (3), 271-285, 2012 | 333 | 2012 |
Chronic dry eye disease is principally mediated by effector memory Th17 cells Y Chen, SK Chauhan, HS Lee, DR Saban, R Dana Mucosal immunology 7 (1), 38-45, 2014 | 109 | 2014 |
Pathological conversion of regulatory T cells is associated with loss of allotolerance J Hua, T Inomata, Y Chen, W Foulsham, W Stevenson, T Shiang, ... Scientific reports 8 (1), 7059, 2018 | 95 | 2018 |
The CCR6/CCL20 axis mediates Th17 cell migration to the ocular surface in dry eye disease TH Dohlman, SK Chauhan, S Kodati, J Hua, Y Chen, M Omoto, Z Sadrai, ... Investigative ophthalmology & visual science 54 (6), 4081-4091, 2013 | 94 | 2013 |
Extraorbital lacrimal gland excision: a reproducible model of severe aqueous tear-deficient dry eye disease W Stevenson, Y Chen, SM Lee, HS Lee, J Hua, T Dohlman, T Shiang, ... Cornea 33 (12), 1336-1341, 2014 | 92 | 2014 |
Interferon-γ-secreting NK cells promote induction of dry eye disease Y Chen, SK Chauhan, DR Saban, Z Sadrai, A Okanobo, R Dana Journal of leukocyte biology 89 (6), 965-972, 2011 | 91 | 2011 |
IFN-γ–Expressing Th17 Cells Are Required for Development of Severe Ocular Surface Autoimmunity Y Chen, SK Chauhan, C Shao, M Omoto, T Inomata, R Dana The Journal of Immunology 199 (3), 1163-1169, 2017 | 88 | 2017 |
In vivo expansion of regulatory T cells by low-dose interleukin-2 treatment increases allograft survival in corneal transplantation M Tahvildari, M Omoto, Y Chen, P Emami-Naeini, T Inomata, TH Dohlman, ... Transplantation 100 (3), 525-532, 2016 | 86 | 2016 |
Effect of desiccating environmental stress versus systemic muscarinic AChR blockade on dry eye immunopathogenesis Y Chen, SK Chauhan, HS Lee, W Stevenson, CS Schaumburg, Z Sadrai, ... Investigative ophthalmology & visual science 54 (4), 2457-2464, 2013 | 64 | 2013 |
The resolvin D1 analogue controls maturation of dendritic cells and suppresses alloimmunity in corneal transplantation J Hua, Y Jin, Y Chen, T Inomata, HS Lee, SK Chauhan, NA Petasis, ... Investigative ophthalmology & visual science 55 (9), 5944-5951, 2014 | 57 | 2014 |
CCR7 is critical for the induction and maintenance of Th17 immunity in dry eye disease S Kodati, SK Chauhan, Y Chen, TH Dohlman, P Karimian, D Saban, ... Investigative ophthalmology & visual science 55 (9), 5871-5877, 2014 | 57 | 2014 |
Interleukin-7 and-15 maintain pathogenic memory Th17 cells in autoimmunity Y Chen, SK Chauhan, X Tan, R Dana Journal of autoimmunity 77, 96-103, 2017 | 54 | 2017 |
Soluble vascular endothelial growth factor receptor-3 suppresses allosensitization and promotes corneal allograft survival P Emami-Naeini, TH Dohlman, M Omoto, T Hattori, Y Chen, HS Lee, ... Graefe's Archive for Clinical and Experimental Ophthalmology 252, 1755-1762, 2014 | 40 | 2014 |
Neurokinin-1 receptor antagonism ameliorates dry eye disease by inhibiting antigen-presenting cell maturation and T Helper 17 cell activation M Yu, SM Lee, H Lee, A Amouzegar, T Nakao, Y Chen, R Dana The American Journal of Pathology 190 (1), 125-133, 2020 | 36 | 2020 |
Restoration of regulatory T-cell function in dry eye disease by antagonizing substance P/Neurokinin-1 receptor Y Taketani, A Marmalidou, TH Dohlman, RB Singh, A Amouzegar, ... The American Journal of Pathology 190 (9), 1859-1866, 2020 | 34 | 2020 |
PDE4 inhibition suppresses IL-17–associated immunity in dry eye disease Z Sadrai, W Stevenson, A Okanobo, Y Chen, TH Dohlman, J Hua, ... Investigative ophthalmology & visual science 53 (7), 3584-3591, 2012 | 33 | 2012 |
Autoimmunity in dry eye disease–An updated review of evidence on effector and memory Th17 cells in disease pathogenicity Y Chen, R Dana Autoimmunity Reviews 20 (11), 102933, 2021 | 32 | 2021 |
The role of Th17 immunity in chronic ocular surface disorders NW Fan, TH Dohlman, W Foulsham, M McSoley, RB Singh, Y Chen, ... The ocular surface 19, 157-168, 2021 | 32 | 2021 |
The immunoregulatory role of corneal epithelium-derived thrombospondin-1 in dry eye disease X Tan, Y Chen, W Foulsham, A Amouzegar, T Inomata, Y Liu, ... The ocular surface 16 (4), 470-477, 2018 | 32 | 2018 |
The function of regulatory T cells at the ocular surface W Foulsham, A Marmalidou, A Amouzegar, G Coco, Y Chen, R Dana The ocular surface 15 (4), 652-659, 2017 | 29 | 2017 |