关注
Hao Chen
Hao Chen
University of Tennessee Health Science Center
在 uthsc.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Tubulin inhibitor-based antibody-drug conjugates for cancer therapy
H Chen, Z Lin, KE Arnst, DD Miller, W Li
Molecules 22 (8), 1281, 2017
1822017
Current advances of tubulin inhibitors as dual acting small molecules for cancer therapy
KE Arnst, S Banerjee, H Chen, S Deng, DJ Hwang, W Li, DD Miller
Medicinal research reviews 39 (4), 1398-1426, 2019
1232019
Mechanism of microtubule stabilization by taccalonolide AJ
Y Wang, Y Yu, GB Li, SA Li, C Wu, B Gigant, W Qin, H Chen, Y Wu, ...
Nature communications 8 (1), 15787, 2017
742017
Polycystin-1 interacts with TAZ to stimulate osteoblastogenesis and inhibit adipogenesis
Z Xiao, J Baudry, L Cao, J Huang, H Chen, CR Yates, W Li, B Dong, ...
The Journal of clinical investigation 128 (1), 157-174, 2018
672018
DYRK1A inhibitors for disease therapy: Current status and perspectives
T Liu, Y Wang, J Wang, C Ren, H Chen, J Zhang
European journal of medicinal chemistry 229, 114062, 2022
632022
Design, synthesis, and anticancer evaluation of novel quinoline derivatives of ursolic acid with hydrazide, oxadiazole, and thiadiazole moieties as potent MEK inhibitors
XY Jin, H Chen, DD Li, AL Li, WY Wang, W Gu
Journal of enzyme inhibition and medicinal chemistry 34 (1), 955-972, 2019
592019
Design, synthesis and in vitro anticancer activity of novel quinoline and oxadiazole derivatives of ursolic acid
W Gu, XY Jin, DD Li, SF Wang, XB Tao, H Chen
Bioorganic & Medicinal Chemistry Letters 27 (17), 4128-4132, 2017
572017
A novel carbazole-based mitochondria-targeted ratiometric fluorescent probe for bisulfite in living cells
G Wang, H Chen, X Chen, Y Xie
RSC advances 6 (22), 18662-18666, 2016
492016
Structural modification of the 3, 4, 5-trimethoxyphenyl moiety in the tubulin inhibitor VERU-111 leads to improved antiproliferative activities
Q Wang, KE Arnst, Y Wang, G Kumar, D Ma, H Chen, Z Wu, J Yang, ...
Journal of medicinal chemistry 61 (17), 7877-7891, 2018
462018
Synthesis, characterization and targeting chemotherapy for ovarian cancer of trastuzumab-SN-38 conjugates
Y Yao, L Yu, X Su, Y Wang, W Li, Y Wu, X Cheng, H Zhang, X Wei, ...
Journal of Controlled Release 220, 5-17, 2015
412015
Structure–activity relationship study of novel 6-aryl-2-benzoyl-pyridines as tubulin polymerization inhibitors with potent antiproliferative properties
H Chen, S Deng, Y Wang, N Albadari, G Kumar, D Ma, W Li, SW White, ...
Journal of Medicinal Chemistry 63 (2), 827-846, 2019
402019
Design, synthesis, and biological evaluation of stable colchicine-binding site tubulin inhibitors 6-aryl-2-benzoyl-pyridines as potential anticancer agents
H Chen, S Deng, N Albadari, MK Yun, S Zhang, Y Li, D Ma, DN Parke, ...
Journal of medicinal chemistry 64 (16), 12049-12074, 2021
362021
Synthesis and biological evaluation of 2-aryl-benzimidazole derivatives of dehydroabietic acid as novel tubulin polymerization inhibitors
TT Miao, XB Tao, DD Li, H Chen, XY Jin, Y Geng, SF Wang, W Gu
RSC advances 8 (31), 17511-17526, 2018
342018
Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site
Q Lai, Y Wang, R Wang, W Lai, L Tang, Y Tao, Y Liu, R Zhang, L Huang, ...
European Journal of Medicinal Chemistry 156, 162-179, 2018
322018
1α,20S-Dihydroxyvitamin D3 Interacts with Vitamin D Receptor: Crystal Structure and Route of Chemical Synthesis
Z Lin, H Chen, AY Belorusova, JC Bollinger, EKY Tang, Z Janjetovic, ...
Scientific reports 7 (1), 10193, 2017
312017
A hypoxia-specific and mitochondria-targeted anticancer theranostic agent with high selectivity for cancer cells
M Hu, C Yang, Y Luo, F Chen, F Yang, S Yang, H Chen, Z Cheng, K Li, ...
Journal of materials chemistry B 6 (16), 2413-2416, 2018
302018
An orally available tubulin inhibitor, VERU-111, suppresses triple-negative breast cancer tumor growth and metastasis and bypasses taxane resistance
S Deng, RI Krutilina, Q Wang, Z Lin, DN Parke, HC Playa, H Chen, ...
Molecular cancer therapeutics 19 (2), 348-363, 2020
292020
Nifuroxazide induces apoptosis, inhibits cell migration and invasion in osteosarcoma
Y Luo, A Zeng, A Fang, L Song, C Fan, C Zeng, T Ye, H Chen, C Tu, Y Xie
Investigational New Drugs 37, 1006-1013, 2019
242019
Orally available tubulin inhibitor VERU-111 enhances antitumor efficacy in paclitaxel-resistant lung cancer
F Mahmud, S Deng, H Chen, DD Miller, W Li
Cancer letters 495, 76-88, 2020
232020
Dual-target inhibitors of poly (ADP-ribose) polymerase-1 for cancer therapy: Advances, challenges, and opportunities
X Hu, J Zhang, Y Zhang, F Jiao, J Wang, H Chen, L Ouyang, Y Wang
European Journal of Medicinal Chemistry 230, 114094, 2022
212022
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