| ATR inhibition disrupts rewired homologous recombination and fork protection pathways in PARP inhibitor-resistant BRCA-deficient cancer cells SA Yazinski, V Comaills, R Buisson, MM Genois, HD Nguyen, CK Ho, ... Genes & development 31 (3), 318-332, 2017 | 357 | 2017 |
| A mitosis-specific and R loop–driven ATR pathway promotes faithful chromosome segregation L Kabeche, HD Nguyen, R Buisson, L Zou Science 359 (6371), 108-114, 2018 | 281 | 2018 |
| PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry A Maréchal, JM Li, XY Ji, CS Wu, SA Yazinski, HD Nguyen, S Liu, ... Molecular cell 53 (2), 235-246, 2014 | 265 | 2014 |
| Functions of replication protein A as a sensor of R loops and a regulator of RNaseH1 HD Nguyen, T Yadav, S Giri, B Saez, TA Graubert, L Zou Molecular cell 65 (5), 832-847. e4, 2017 | 262 | 2017 |
| Two distinct modes of ATR activation orchestrated by Rad17 and Nbs1 B Shiotani, HD Nguyen, P Håkansson, A Maréchal, A Tse, H Tahara, ... Cell reports 3 (5), 1651-1662, 2013 | 157 | 2013 |
| Spliceosome mutations induce R loop-associated sensitivity to ATR inhibition in myelodysplastic syndromes HD Nguyen, WY Leong, W Li, PNG Reddy, JD Sullivan, MJ Walter, L Zou, ... Cancer research 78 (18), 5363-5374, 2018 | 147 | 2018 |
| ATR protects the genome against R loops through a MUS81-triggered feedback loop DA Matos, JM Zhang, J Ouyang, HD Nguyen, MM Genois, L Zou Molecular cell 77 (3), 514-527. e4, 2020 | 113 | 2020 |
| Noncovalent interactions with SUMO and ubiquitin orchestrate distinct functions of the SLX4 complex in genome maintenance J Ouyang, E Garner, A Hallet, HD Nguyen, KA Rickman, G Gill, ... Molecular cell 57 (1), 108-122, 2015 | 87 | 2015 |
| SUMOylation of ATRIP potentiates DNA damage signaling by boosting multiple protein interactions in the ATR pathway CS Wu, J Ouyang, E Mori, HD Nguyen, A Maréchal, A Hallet, DJ Chen, ... Genes & development 28 (13), 1472-1484, 2014 | 78 | 2014 |
| Defects in DNA ligase I trigger PCNA ubiquitylation at Lys 107 S Das-Bradoo, HD Nguyen, JL Wood, RM Ricke, JC Haworth, ... Nature cell biology 12 (1), 74-79, 2010 | 78 | 2010 |
| Slx5/Slx8 promotes replication stress tolerance by facilitating mitotic progression YM Thu, SK Van Riper, LA Higgins, T Zhang, JR Becker, TW Markowski, ... Cell reports 15 (6), 1254-1265, 2016 | 43 | 2016 |
| Flap endonuclease overexpression drives genome instability and DNA damage hypersensitivity in a PCNA-dependent manner JR Becker, D Gallo, W Leung, T Croissant, YM Thu, HD Nguyen, TK Starr, ... Nucleic acids research 46 (11), 5634-5650, 2018 | 40 | 2018 |
| Genetic interactions implicating postreplicative repair in Okazaki fragment processing JR Becker, C Pons, HD Nguyen, M Costanzo, C Boone, CL Myers, ... PLoS genetics 11 (11), e1005659, 2015 | 35 | 2015 |
| Unligated Okazaki fragments induce PCNA ubiquitination and a requirement for Rad59-dependent replication fork progression HD Nguyen, J Becker, YM Thu, M Costanzo, EN Koch, S Smith, K Myung, ... PLoS One 8 (6), e66379, 2013 | 35 | 2013 |
| Mcm10 deficiency causes defective-replisome-induced mutagenesis and a dependency on error-free postreplicative repair JR Becker, HD Nguyen, X Wang, AK Bielinsky Cell Cycle 13 (11), 1737-1748, 2014 | 30 | 2014 |
| PARP1 associates with R-loops to promote their resolution and genome stability N Laspata, P Kaur, SY Mersaoui, D Muoio, ZS Liu, MH Bannister, ... Nucleic acids research 51 (5), 2215-2237, 2023 | 28 | 2023 |
| Damage-specific modification of PCNA S Das-Bradoo, HD Nguyen, AK Bielinsky Cell Cycle 9 (18), 3698-3703, 2010 | 19 | 2010 |
| Targeting R-loop-associated ATR response in myelodysplastic syndrome HD Nguyen, L Zou, TA Graubert Oncotarget 10 (27), 2581, 2019 | 11 | 2019 |
| Identification of formaldehyde-induced DNA–RNA cross-links in the A/J mouse lung tumorigenesis model RP Dator, KJ Murray, MW Luedtke, FC Jacobs, F Kassie, HD Nguyen, ... Chemical research in toxicology 35 (11), 2025-2036, 2022 | 10 | 2022 |
| Hå kansson B Shiotani, HD Nguyen P., Maré chal, A., Tse, A., Tahara, H., and Zou, L, 1651-1662, 2013 | 9 | 2013 |
