Bacterial growth and cell division: a mycobacterial perspective EC Hett, EJ Rubin Microbiology and Molecular Biology Reviews 72 (1), 126-156, 2008 | 617 | 2008 |
A road map to evaluate the proteome-wide selectivity of covalent kinase inhibitors BR Lanning, LR Whitby, MM Dix, J Douhan, AM Gilbert, EC Hett, ... Nature chemical biology 10 (9), 760-767, 2014 | 375 | 2014 |
Microenvironment mapping via Dexter energy transfer on immune cells JB Geri, JV Oakley, T Reyes-Robles, T Wang, SJ McCarver, CH White, ... Science 367 (6482), 1091-1097, 2020 | 257 | 2020 |
A partner for the resuscitation‐promoting factors of Mycobacterium tuberculosis EC Hett, MC Chao, AJ Steyn, SM Fortune, LL Deng, EJ Rubin Molecular microbiology 66 (3), 658-668, 2007 | 210 | 2007 |
A mycobacterial enzyme essential for cell division synergizes with resuscitation-promoting factor EC Hett, MC Chao, LL Deng, EJ Rubin PLoS pathogens 4 (2), e1000001, 2008 | 204 | 2008 |
Rational targeting of active-site tyrosine residues using sulfonyl fluoride probes EC Hett, H Xu, KF Geoghegan, A Gopalsamy, RE Kyne Jr, CA Menard, ... ACS Chemical Biology 10 (4), 1094-1098, 2015 | 175 | 2015 |
The potential of virulent Wolbachia to modulate disease transmission by insects JS Brownstein, E Hett, SL O’Neill Journal of invertebrate pathology 84 (1), 24-29, 2003 | 174 | 2003 |
Discovery of a JAK3-selective inhibitor: functional differentiation of JAK3-selective inhibition over pan-JAK or JAK1-selective inhibition JB Telliez, ME Dowty, L Wang, J Jussif, T Lin, L Li, E Moy, P Balbo, W Li, ... ACS chemical biology 11 (12), 3442-3451, 2016 | 162 | 2016 |
Interaction and modulation of two antagonistic cell wall enzymes of mycobacteria EC Hett, MC Chao, EJ Rubin PLoS pathogens 6 (7), e1001020, 2010 | 161 | 2010 |
Know your target, know your molecule ME Bunnage, AM Gilbert, LH Jones, EC Hett Nature chemical biology 11 (6), 368-372, 2015 | 116 | 2015 |
Covalent enzyme inhibition through fluorosulfate modification of a noncatalytic serine residue OO Fadeyi, LR Hoth, C Choi, X Feng, A Gopalsamy, EC Hett, RE Kyne Jr, ... ACS Chemical Biology 12 (8), 2015-2020, 2017 | 109 | 2017 |
Mycobacterium tuberculosis Rv2224c modulates innate immune responses J Rengarajan, E Murphy, A Park, CL Krone, EC Hett, BR Bloom, ... Proceedings of the National Academy of Sciences 105 (1), 264-269, 2008 | 99 | 2008 |
Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis EC Hett, LH Slater, KG Mark, T Kawate, BG Monks, A Stutz, E Latz, ... Nature chemical biology 9 (6), 398-405, 2013 | 87 | 2013 |
Understanding and applying tyrosine biochemical diversity LH Jones, A Narayanan, EC Hett Molecular BioSystems 10 (5), 952-969, 2014 | 77 | 2014 |
Detection of cell–cell interactions via photocatalytic cell tagging RC Oslund, T Reyes-Robles, CH White, JH Tomlinson, KA Crotty, ... Nature Chemical Biology 18 (8), 850-858, 2022 | 59 | 2022 |
Colorectal cancer-associated anaerobic bacteria proliferate in tumor spheroids and alter the microenvironment SH Kasper, C Morell-Perez, TP Wyche, TR Sana, LA Lieberman, EC Hett Scientific reports 10 (1), 5321, 2020 | 56 | 2020 |
Follicular T cells optimize the germinal center response to SARS-CoV-2 protein vaccination in mice CB Cavazzoni, BL Hanson, MA Podestà, ED Bechu, RL Clement, ... Cell reports 38 (8), 2022 | 41 | 2022 |
Microfluidic-enabled intracellular delivery of membrane impermeable inhibitors to study target engagement in human primary cells J Li, B Wang, BM Juba, M Vazquez, SW Kortum, BS Pierce, M Pacheco, ... ACS chemical biology 12 (12), 2970-2974, 2017 | 41 | 2017 |
CDK12-mediated transcriptional regulation of noncanonical NF-κB components is essential for signaling KL Henry, D Kellner, B Bajrami, JE Anderson, M Beyna, G Bhisetti, ... Science signaling 11 (541), eaam8216, 2018 | 35 | 2018 |
Cellular thermal shift and clickable chemical probe assays for the determination of drug-target engagement in live cells H Xu, A Gopalsamy, EC Hett, S Salter, A Aulabaugh, RE Kyne, B Pierce, ... Organic & Biomolecular Chemistry 14 (26), 6179-6183, 2016 | 25 | 2016 |