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Erik Hett
Erik Hett
Merck, Biogen, Pfizer, Broad Institute, Harvard
在 merck.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Bacterial growth and cell division: a mycobacterial perspective
EC Hett, EJ Rubin
Microbiology and Molecular Biology Reviews 72 (1), 126-156, 2008
6172008
A road map to evaluate the proteome-wide selectivity of covalent kinase inhibitors
BR Lanning, LR Whitby, MM Dix, J Douhan, AM Gilbert, EC Hett, ...
Nature chemical biology 10 (9), 760-767, 2014
3752014
Microenvironment mapping via Dexter energy transfer on immune cells
JB Geri, JV Oakley, T Reyes-Robles, T Wang, SJ McCarver, CH White, ...
Science 367 (6482), 1091-1097, 2020
2572020
A partner for the resuscitation‐promoting factors of Mycobacterium tuberculosis
EC Hett, MC Chao, AJ Steyn, SM Fortune, LL Deng, EJ Rubin
Molecular microbiology 66 (3), 658-668, 2007
2102007
A mycobacterial enzyme essential for cell division synergizes with resuscitation-promoting factor
EC Hett, MC Chao, LL Deng, EJ Rubin
PLoS pathogens 4 (2), e1000001, 2008
2042008
Rational targeting of active-site tyrosine residues using sulfonyl fluoride probes
EC Hett, H Xu, KF Geoghegan, A Gopalsamy, RE Kyne Jr, CA Menard, ...
ACS Chemical Biology 10 (4), 1094-1098, 2015
1752015
The potential of virulent Wolbachia to modulate disease transmission by insects
JS Brownstein, E Hett, SL O’Neill
Journal of invertebrate pathology 84 (1), 24-29, 2003
1742003
Discovery of a JAK3-selective inhibitor: functional differentiation of JAK3-selective inhibition over pan-JAK or JAK1-selective inhibition
JB Telliez, ME Dowty, L Wang, J Jussif, T Lin, L Li, E Moy, P Balbo, W Li, ...
ACS chemical biology 11 (12), 3442-3451, 2016
1622016
Interaction and modulation of two antagonistic cell wall enzymes of mycobacteria
EC Hett, MC Chao, EJ Rubin
PLoS pathogens 6 (7), e1001020, 2010
1612010
Know your target, know your molecule
ME Bunnage, AM Gilbert, LH Jones, EC Hett
Nature chemical biology 11 (6), 368-372, 2015
1162015
Covalent enzyme inhibition through fluorosulfate modification of a noncatalytic serine residue
OO Fadeyi, LR Hoth, C Choi, X Feng, A Gopalsamy, EC Hett, RE Kyne Jr, ...
ACS Chemical Biology 12 (8), 2015-2020, 2017
1092017
Mycobacterium tuberculosis Rv2224c modulates innate immune responses
J Rengarajan, E Murphy, A Park, CL Krone, EC Hett, BR Bloom, ...
Proceedings of the National Academy of Sciences 105 (1), 264-269, 2008
992008
Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis
EC Hett, LH Slater, KG Mark, T Kawate, BG Monks, A Stutz, E Latz, ...
Nature chemical biology 9 (6), 398-405, 2013
872013
Understanding and applying tyrosine biochemical diversity
LH Jones, A Narayanan, EC Hett
Molecular BioSystems 10 (5), 952-969, 2014
772014
Detection of cell–cell interactions via photocatalytic cell tagging
RC Oslund, T Reyes-Robles, CH White, JH Tomlinson, KA Crotty, ...
Nature Chemical Biology 18 (8), 850-858, 2022
592022
Colorectal cancer-associated anaerobic bacteria proliferate in tumor spheroids and alter the microenvironment
SH Kasper, C Morell-Perez, TP Wyche, TR Sana, LA Lieberman, EC Hett
Scientific reports 10 (1), 5321, 2020
562020
Follicular T cells optimize the germinal center response to SARS-CoV-2 protein vaccination in mice
CB Cavazzoni, BL Hanson, MA Podestà, ED Bechu, RL Clement, ...
Cell reports 38 (8), 2022
412022
Microfluidic-enabled intracellular delivery of membrane impermeable inhibitors to study target engagement in human primary cells
J Li, B Wang, BM Juba, M Vazquez, SW Kortum, BS Pierce, M Pacheco, ...
ACS chemical biology 12 (12), 2970-2974, 2017
412017
CDK12-mediated transcriptional regulation of noncanonical NF-κB components is essential for signaling
KL Henry, D Kellner, B Bajrami, JE Anderson, M Beyna, G Bhisetti, ...
Science signaling 11 (541), eaam8216, 2018
352018
Cellular thermal shift and clickable chemical probe assays for the determination of drug-target engagement in live cells
H Xu, A Gopalsamy, EC Hett, S Salter, A Aulabaugh, RE Kyne, B Pierce, ...
Organic & Biomolecular Chemistry 14 (26), 6179-6183, 2016
252016
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