| 10-Iodo-11H-indolo[3,2-c]quinoline-6-carboxylic Acids Are Selective Inhibitors of DYRK1A H Falke, A Chaikuad, A Becker, N Loaëc, O Lozach, S Abu Jhaisha, ... Journal of medicinal chemistry 58 (7), 3131-3143, 2015 | 118 | 2015 |
| 3,6-Diamino-4-(2-halophenyl)-2-benzoylthieno[2,3-b]pyridine-5-carbonitriles Are Selective Inhibitors of Plasmodium falciparum Glycogen Synthase Kinase-3 W Fugel, AE Oberholzer, B Gschloessl, R Dzikowski, N Pressburger, ... Journal of medicinal chemistry 56 (1), 264-275, 2013 | 79 | 2013 |
| Identification of 2-Anilino-9-methoxy-5,7-dihydro-6H-pyrimido[5,4-d][1]benzazepin-6-ones as Dual PLK1/VEGF-R2 Kinase Inhibitor Chemotypes by Structure … AM Egert-Schmidt, J Dreher, U Dunkel, S Kohfeld, L Preu, H Weber, ... Journal of medicinal chemistry 53 (6), 2433-2442, 2010 | 74 | 2010 |
| Inhibitors of the RET tyrosine kinase based on a 2-(alkylsulfanyl)-4-(3-thienyl) nicotinonitrile scaffold W Brandt, L Mologni, L Preu, T Lemcke, C Gambacorti-Passerini, ... European journal of medicinal chemistry 45 (7), 2919-2927, 2010 | 66 | 2010 |
| Evaluation of monolithic HPLC columns for various pharmaceutical separations: Method transfer from conventional phases and batch to batch repeatability S El Deeb, L Preu, H Wätzig Journal of pharmaceutical and biomedical analysis 44 (1), 85-95, 2007 | 51 | 2007 |
| 2-Anilino-4-(benzimidazol-2-yl) pyrimidines–A multikinase inhibitor scaffold with antiproliferative activity toward cancer cell lines R Determann, J Dreher, K Baumann, L Preu, PG Jones, F Totzke, ... European journal of medicinal chemistry 53, 254-263, 2012 | 49 | 2012 |
| Structural studies of organoboron compounds. XXIV. 5-Methyl-5-nitro-2-phenyl-1, 3-dioxa-2-boracyclohexane W Kliegel, L Preu, SJ Rettig, J Trotter Canadian journal of chemistry 64 (9), 1855-1858, 1986 | 40 | 1986 |
| 9-and 11-substituted 4-azapaullones are potent and selective inhibitors of African trypanosoma F Maiwald, D Benítez, D Charquero, MA Dar, H Erdmann, L Preu, O Koch, ... European Journal of Medicinal Chemistry 83, 274-283, 2014 | 38 | 2014 |
| Wide concentration range investigation of recovery, precision and error structure in liquid chromatography U Schepers, J Ermer, L Preu, H Wätzig Journal of Chromatography B 810 (1), 111-118, 2004 | 38 | 2004 |
| Indole-3-carbonitriles as DYRK1A inhibitors by fragment-based drug design R Meine, W Becker, H Falke, L Preu, N Loaëc, L Meijer, C Kunick Molecules 23 (2), 64, 2018 | 34 | 2018 |
| Development of 5-benzylpaullones and paullone-9-carboxylic acid alkyl esters as selective inhibitors of mitochondrial malate dehydrogenase (mMDH) A Becker, S Kohfeld, A Lader, L Preu, T Pies, K Wieking, Y Ferandin, ... European journal of medicinal chemistry 45 (1), 335-342, 2010 | 31 | 2010 |
| Structural studies of organoboron compounds. XXI. Crystal and molecular structures of 3-(phenylmethylidene)-4-methyl-1-phenyl-2, 6, 7-trioxa-3-azonia-1-boratabicyclo-[2.2. 2 … W Kliegel, L Preu, SJ Rettig, J Trotter Canadian journal of chemistry 63 (2), 509-515, 1985 | 30 | 1985 |
| 2-Arylpaullones are selective antitrypanosomal agents J Ryczak, M Papini, A Lader, A Nasereddin, D Kopelyanskiy, L Preu, ... European Journal of Medicinal Chemistry 64, 396-400, 2013 | 29 | 2013 |
| A strategy to develop fast RP‐HPLC methods using monolithic silica columns S El Deeb, L Preu, H Wätzig Journal of separation science 30 (13), 1993-2001, 2007 | 29 | 2007 |
| Structure–activity relationships in a series of antiplasmodial thieno[2,3-b]pyridines A Masch, A Nasereddin, A Alder, MJ Bird, SI Schweda, L Preu, C Doerig, ... Malaria journal 18, 1-10, 2019 | 28 | 2019 |
| Molecular structures of cdc2-like kinases in complex with a new inhibitor chemotype A Walter, A Chaikuad, R Helmer, N Loaëc, L Preu, I Ott, S Knapp, L Meijer, ... PLoS One 13 (5), e0196761, 2018 | 25 | 2018 |
| 5-Substituted 3-chlorokenpaullone derivatives are potent inhibitors of Trypanosoma brucei bloodstream forms OCF Orban, RS Korn, D Benítez, A Medeiros, L Preu, N Loaëc, L Meijer, ... Bioorganic & Medicinal Chemistry 24 (16), 3790-3800, 2016 | 25 | 2016 |
| Dimroth‐Umlagerung von Iminen des 1, 5‐Diaminotetrazols D Moderhack, KH Goos, L Preu Chemische Berichte 123 (7), 1575-1578, 1990 | 25 | 1990 |
| Parenteral formulation of an antileishmanial drug candidate–Tackling poor solubility, chemical instability, and polymorphism E Kupetz, L Preu, C Kunick, H Bunjes European Journal of Pharmaceutics and Biopharmaceutics 85 (3), 511-520, 2013 | 19 | 2013 |
| Separation of cold medicine ingredients using a precise MEKC method at elevated pH P Hasemann, M ter Balk, L Preu, H Wätzig Electrophoresis 28 (11), 1779-1787, 2007 | 18 | 2007 |
