Scan of human genome reveals no new loci under ancient balancing selection KL Bubb, D Bovee, D Buckley, E Haugen, M Kibukawa, M Paddock, ... Genetics 173 (4), 2165-2177, 2006 | 154 | 2006 |
Minimal introns are not “junk” J Yu, Z Yang, M Kibukawa, M Paddock, DA Passey, GKS Wong Genome Research 12 (8), 1185-1189, 2002 | 101 | 2002 |
Mitochondrial one-carbon pathway supports cytosolic folate integrity in cancer cells Y Zheng, TY Lin, G Lee, MN Paddock, J Momb, Z Cheng, Q Li, DL Fei, ... Cell 175 (6), 1546-1560. e17, 2018 | 95 | 2018 |
Competition between PARP-1 and Ku70 control the decision between high-fidelity and mutagenic DNA repair MN Paddock, AT Bauman, R Higdon, E Kolker, S Takeda, ... DNA repair 10 (3), 338-343, 2011 | 88 | 2011 |
Ancient haplotypes of the HLA Class II region CK Raymond, A Kas, M Paddock, R Qiu, Y Zhou, S Subramanian, ... Genome Research 15 (9), 1250-1257, 2005 | 82 | 2005 |
The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity CK Baumgartner, H Ebrahimi-Nik, A Iracheta-Vellve, KM Hamel, ... Nature 622 (7984), 850-862, 2023 | 76 | 2023 |
Catecholamines in patients with 22q11. 2 deletion syndrome and the low-activity COMT polymorphism WD Graf, AS Unis, CM Yates, S Sulzbacher, MB Dinulos, RM Jack, ... Neurology 57 (3), 410-416, 2001 | 76 | 2001 |
A population threshold for functional polymorphisms GKS Wong, Z Yang, DA Passey, M Kibukawa, M Paddock, CR Liu, ... Genome research 13 (8), 1873-1879, 2003 | 54 | 2003 |
The INPP4B tumor suppressor modulates EGFR trafficking and promotes triple-negative breast cancer H Liu, MN Paddock, H Wang, CJ Murphy, RC Geck, AJ Navarro, GM Wulf, ... Cancer Discovery 10 (8), 1226-1239, 2020 | 50 | 2020 |
PIP4Ks suppress insulin signaling through a catalytic-independent mechanism DG Wang, MN Paddock, MR Lundquist, JY Sun, O Mashadova, ... Cell reports 27 (7), 1991-2001. e5, 2019 | 48 | 2019 |
Targeting the PI5P4K lipid kinase family in cancer using covalent inhibitors SC Sivakumaren, H Shim, T Zhang, FM Ferguson, MR Lundquist, ... Cell chemical biology 27 (5), 525-537. e6, 2020 | 40 | 2020 |
The BRCT domain of PARP-1 is required for immunoglobulin gene conversion MN Paddock, BD Buelow, S Takeda, AM Scharenberg PLoS biology 8 (7), e1000428, 2010 | 37 | 2010 |
Targeted, haplotype-resolved resequencing of long segments of the human genome CK Raymond, S Subramanian, M Paddock, R Qiu, C Deodato, A Palmieri, ... Genomics 86 (6), 759-766, 2005 | 35 | 2005 |
Treating cancer with phosphatidylinositol-3-kinase inhibitors: increasing efficacy and overcoming resistance MN Paddock, SJ Field, LC Cantley Journal of lipid research 60 (4), 747-752, 2019 | 24 | 2019 |
Structure/function analysis of PARP-1 in oxidative and nitrosative stress-induced monomeric ADPR formation B Buelow, B Uzunparmak, M Paddock, AM Scharenberg PLoS One 4 (7), e6339, 2009 | 20 | 2009 |
Wintrobe's atlas of clinical hematology B Weksler Lippincott Williams & Wilkins, 2017 | 14 | 2017 |
Bleeding Diatheses: Approach to the Patient Who Bleeds or Has Abnormal Coagulation. M Paddock, J Chapin Primary Care 43 (4), 637-650, 2016 | 10 | 2016 |
Abstract CT257: first-in-human phase 1 studies of PTPN2/1 inhibitors ABBV-CLS-484 and ABBV-CLS-579 in locally advanced or metastatic tumors PM LoRusso, EC Aller, N Yamamoto, CC Lin, T Beck, D Sommerhalder, ... Cancer Research 83 (8_Supplement), CT257-CT257, 2023 | 5 | 2023 |
Abstract ND06: ABBV-CLS-484: an active site PTPN2/N1 inhibitor that augments the immune response and sensitizes tumors to immune-mediated killing CK Baumgartner, MN Paddock, JM Frost, KM Hamel, KA McGuire, ... Cancer Research 82 (12_Supplement), ND06-ND06, 2022 | 5 | 2022 |
Epinephrine inhibits PI3Kα via the Hippo kinases TY Lin, S Ramsamooj, T Perrier, K Liberatore, L Lantier, N Vasan, ... Cell reports 42 (12), 2023 | 2 | 2023 |