Lentiviral transduction of mammalian cells for fast, scalable and high-level production of soluble and membrane proteins J Elegheert, E Behiels, B Bishop, S Scott, RE Woolley, SC Griffiths, ... Nature protocols 13 (12), 2991-3017, 2018 | 180 | 2018 |
Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan TH Chang, FL Hsieh, M Zebisch, K Harlos, J Elegheert, EY Jones Elife 4, e06554, 2015 | 125 | 2015 |
Structural basis for integration of GluD receptors within synaptic organizer complexes J Elegheert, W Kakegawa, JE Clay, NF Shanks, E Behiels, K Matsuda, ... Science 353 (6296), 295-299, 2016 | 122 | 2016 |
Structural insights into the extracellular assembly of the hematopoietic Flt3 signaling complex K Verstraete, G Vandriessche, M Januar, J Elegheert, AV Shkumatov, ... Blood, The Journal of the American Society of Hematology 118 (1), 60-68, 2011 | 102 | 2011 |
Repulsive guidance molecule is a structural bridge between neogenin and bone morphogenetic protein EG Healey, B Bishop, J Elegheert, CH Bell, S Padilla-Parra, C Siebold Nature structural & molecular biology 22 (6), 458-465, 2015 | 96 | 2015 |
A synthetic synaptic organizer protein restores glutamatergic neuronal circuits K Suzuki, J Elegheert, I Song, H Sasakura, O Senkov, K Matsuda, ... Science 369 (6507), eabb4853, 2020 | 89 | 2020 |
Structural basis for extracellular cis and trans RPTPσ signal competition in synaptogenesis CH Coles, N Mitakidis, P Zhang, J Elegheert, W Lu, AW Stoker, ... Nature communications 5 (1), 5209, 2014 | 79 | 2014 |
Human IL-34 and CSF-1 establish structurally similar extracellular assemblies with their common hematopoietic receptor J Felix, J Elegheert, I Gutsche, AV Shkumatov, Y Wen, N Bracke, ... Structure 21 (4), 528-539, 2013 | 78 | 2013 |
Glutathione import in Haemophilus influenzae Rd is primed by the periplasmic heme-binding protein HbpA B Vergauwen, J Elegheert, A Dansercoer, B Devreese, SN Savvides Proceedings of the National Academy of Sciences 107 (30), 13270-13275, 2010 | 75 | 2010 |
Structural mechanism for modulation of synaptic neuroligin-neurexin signaling by MDGA proteins J Elegheert, V Cvetkovska, AJ Clayton, C Heroven, KM Vennekens, ... Neuron 95 (4), 896-913. e10, 2017 | 73 | 2017 |
The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence Y Wen, E Behiels, J Felix, J Elegheert, B Vergauwen, B Devreese, ... Nucleic Acids Research 42 (15), 10134-10147, 2014 | 49 | 2014 |
Allosteric competitive inactivation of hematopoietic CSF-1 signaling by the viral decoy receptor BARF1 J Elegheert, N Bracke, P Pouliot, I Gutsche, AV Shkumatov, N Tarbouriech, ... Nature structural & molecular biology 19 (9), 938-947, 2012 | 44 | 2012 |
Structure and assembly mechanism of the signaling complex mediated by human CSF-1 J Felix, S De Munck, K Verstraete, L Meuris, N Callewaert, J Elegheert, ... Structure 23 (9), 1621-1631, 2015 | 41 | 2015 |
Extracellular complexes of the hematopoietic human and mouse CSF-1 receptor are driven by common assembly principles J Elegheert, A Desfosses, AV Shkumatov, X Wu, N Bracke, K Verstraete, ... Structure 19 (12), 1762-1772, 2011 | 40 | 2011 |
Pumping the brakes: suppression of synapse development by MDGA–neuroligin interactions SA Connor, J Elegheert, Y Xie, AM Craig Current Opinion in Neurobiology 57, 71-80, 2019 | 29 | 2019 |
Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling RA Robinson, SC Griffiths, LL van de Haar, T Malinauskas, ... Cell 184 (8), 2103-2120. e31, 2021 | 27 | 2021 |
nandb—number and brightness in R with a novel automatic detrending algorithm R Nolan, LAJ Alvarez, J Elegheert, M Iliopoulou, GM Jakobsdottir, ... Bioinformatics 33 (21), 3508-3510, 2017 | 20 | 2017 |
Inducible production of recombinant human Flt3 ectodomain variants in mammalian cells and preliminary crystallographic analysis of Flt3 ligand–receptor complexes K Verstraete, B Remmerie, J Elegheert, B Lintermans, G Haegeman, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2011 | 13 | 2011 |
Structural dissection of Shewanella oneidensis old yellow enzyme 4 bound to a Meisenheimer complex and (nitro)phenolic ligands J Elegheert, A Brigé, J Van Beeumen, SN Savvides FEBS letters 591 (20), 3391-3401, 2017 | 9 | 2017 |
High-level production of recombinant eukaryotic proteins from mammalian cells using lentivirus E Behiels, J Elegheert Structural Proteomics: High-Throughput Methods, 83-104, 2021 | 5 | 2021 |