New cofactor supports α, β-unsaturated acid decarboxylation via 1, 3-dipolar cycloaddition KAP Payne, MD White, K Fisher, B Khara, SS Bailey, D Parker, ... Nature 522 (7557), 497, 2015 | 227 | 2015 |
UbiX is a flavin prenyltransferase required for bacterial ubiquinone biosynthesis MD White, KAP Payne, K Fisher, SA Marshall, D Parker, NJW Rattray, ... Nature 522 (7557), 502, 2015 | 200 | 2015 |
Plant cysteine oxidases are dioxygenases that directly enable arginyl transferase-catalysed arginylation of N-end rule targets MD White, M Klecker, RJ Hopkinson, DA Weits, C Mueller, C Naumann, ... Nature communications 8, 14690, 2017 | 190 | 2017 |
Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants N Masson, TP Keeley, B Giuntoli, MD White, ML Puerta, P Perata, ... Science 365 (6448), 65-69, 2019 | 182 | 2019 |
Oxygen-dependent proteolysis regulates the stability of angiosperm polycomb repressive complex 2 subunit VERNALIZATION 2 DJ Gibbs, HM Tedds, AM Labandera, M Bailey, MD White, S Hartman, ... Nature communications 9 (1), 5438, 2018 | 90 | 2018 |
The plant cysteine oxidases from Arabidopsis thaliana are kinetically tailored to act as oxygen sensors MD White, JJAG Kamps, S East, LJT Kearney, E Flashman Journal of Biological Chemistry 293 (30), 11786-11795, 2018 | 90 | 2018 |
Catalytic strategies of the non-heme iron dependent oxygenases and their roles in plant biology MD White, E Flashman Current opinion in chemical biology 31, 126-135, 2016 | 84 | 2016 |
Oxidative Maturation and Structural Characterization of Prenylated FMN Binding by UbiD, a Decarboxylase Involved in Bacterial Ubiquinone Biosynthesis SA Marshall, K Fisher, AN Cheallaigh, MD White, KAP Payne, DA Parker, ... Journal of Biological Chemistry 292 (11), 4623-4637, 2017 | 58 | 2017 |
Structures of Arabidopsis thaliana oxygen-sensing plant cysteine oxidases 4 and 5 enable targeted manipulation of their activity MD White, L Dalle Carbonare, ML Puerta, S Iacopino, M Edwards, ... Proceedings of the National Academy of Sciences, 2020 | 40 | 2020 |
The UbiX flavin prenyltransferase reaction mechanism resembles class I terpene cyclase chemistry SA Marshall, KAP Payne, K Fisher, MD White, AN Cheallaigh, ... Nature Communications 10 (1), 2357, 2019 | 34 | 2019 |
Zinc excess induces a hypoxia-like response by inhibiting cysteine oxidases in poplar roots L Dalle Carbonare, M White, V Shukla, A Francini, P Perata, E Flashman, ... Plant physiology, pp. 01458.2018, 2019 | 19 | 2019 |
Intermittent hypoxia enhances the expression of hypoxia inducible factor HIF1A through histone demethylation CA Martinez, Y Jiramongkol, N Bal, I Alwis, PE Nedoboy, MMJ Farnham, ... Journal of Biological Chemistry 298 (11), 2022 | 14 | 2022 |
An integrated platform approach enables discovery of potent, selective and ligand-competitive cyclic peptides targeting the GIP receptor B Bhushan, D Granata, CS Kaas, MA Kasimova, Q Ren, CN Cramer, ... Chemical science 13 (11), 3256-3262, 2022 | 7 | 2022 |
Integrating Phenotypic and Chemoproteomic Approaches to Identify Covalent Targets of Dietary Electrophiles in Platelets IA Guan, JST Liu, RC Sawyer, X Li, W Jiao, Y Jiramongkol, MD White, ... ACS Central Science, 2023 | 1 | 2023 |