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Sophie E Legge
Sophie E Legge
在 cardiff.ac.uk 的电子邮件经过验证
标题
引用次数
引用次数
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Biological insights from 108 schizophrenia-associated genetic loci
C Pantelis, GN Papadimitriou, S Papiol, E Parkhomenko, MT Pato, ...
Nature 511 (7510), 421-427, 2014
74472014
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
AF Pardiñas, P Holmans, AJ Pocklington, V Escott-Price, S Ripke, ...
Nature genetics 50 (3), 381-389, 2018
15362018
Modeling linkage disequilibrium increases accuracy of polygenic risk scores
BJ Vilhjálmsson, J Yang, HK Finucane, A Gusev, S Lindström, S Ripke, ...
The american journal of human genetics 97 (4), 576-592, 2015
13552015
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
V Trubetskoy, AF Pardiñas, T Qi, G Panagiotaropoulou, S Awasthi, ...
Nature 604 (7906), 502-508, 2022
12962022
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
CR Marshall, DP Howrigan, D Merico, B Thiruvahindrapuram, W Wu, ...
Nature genetics 49 (1), 27-35, 2017
9382017
Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases
A Gusev, SH Lee, G Trynka, H Finucane, BJ Vilhjálmsson, H Xu, C Zang, ...
The American Journal of Human Genetics 95 (5), 535-552, 2014
6572014
Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes
DM Ruderfer, S Ripke, A McQuillin, J Boocock, EA Stahl, JMW Pavlides, ...
Cell 173 (7), 1705-1715. e16, 2018
5302018
Analysis of copy number variations at 15 schizophrenia-associated loci
E Rees, JTR Walters, L Georgieva, AR Isles, KD Chambert, AL Richards, ...
The British Journal of Psychiatry 204 (2), 108-114, 2014
4592014
The penetrance of copy number variations for schizophrenia and developmental delay
G Kirov, E Rees, JTR Walters, V Escott-Price, L Georgieva, AL Richards, ...
Biological psychiatry 75 (5), 378-385, 2014
4132014
Evidence that duplications of 22q11. 2 protect against schizophrenia
E Rees, G Kirov, A Sanders, JTR Walters, KD Chambert, J Shi, ...
Molecular Psychiatry 19 (1), 37-40, 2014
1982014
Estimation of genetic correlation via linkage disequilibrium score regression and genomic restricted maximum likelihood
G Ni, G Moser, S Ripke, BM Neale, A Corvin, JTR Walters, KH Farh, ...
The American Journal of Human Genetics 102 (6), 1185-1194, 2018
1522018
Analysis of intellectual disability copy number variants for association with schizophrenia
E Rees, K Kendall, AF Pardiñas, SE Legge, A Pocklington, V Escott-Price, ...
JAMA psychiatry 73 (9), 963-969, 2016
1512016
A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohorts
G Ni, J Zeng, JA Revez, Y Wang, Z Zheng, T Ge, R Restuadi, J Kiewa, ...
Biological psychiatry 90 (9), 611-620, 2021
1432021
De novo mutations identified by exome sequencing implicate rare missense variants in SLC6A1 in schizophrenia
E Rees, J Han, J Morgan, N Carrera, V Escott-Price, AJ Pocklington, ...
Nature neuroscience 23 (2), 179-184, 2020
1342020
Association of genetic liability to psychotic experiences with neuropsychotic disorders and traits
SE Legge, HJ Jones, KM Kendall, AF Pardiñas, G Menzies, ...
JAMA psychiatry 76 (12), 1256-1265, 2019
1332019
Reasons for discontinuing clozapine: a cohort study of patients commencing treatment
SE Legge, M Hamshere, RD Hayes, J Downs, MC O'Donovan, MJ Owen, ...
Schizophrenia research 174 (1-3), 113-119, 2016
1242016
CNV analysis in a large schizophrenia sample implicates deletions at 16p12.1 and SLC1A1 and duplications at 1p36.33 and CGNL1
E Rees, JTR Walters, KD Chambert, C O'Dushlaine, J Szatkiewicz, ...
Human molecular genetics 23 (6), 1669-1676, 2014
1222014
Genetic architecture of schizophrenia: a review of major advancements
SE Legge, ML Santoro, S Periyasamy, A Okewole, A Arsalan, K Kowalec
Psychological medicine 51 (13), 2168-2177, 2021
1182021
Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia
SE Legge, ML Hamshere, S Ripke, AF Pardinas, JI Goldstein, E Rees, ...
Molecular psychiatry 22 (10), 1502-1508, 2017
1032017
The relationship between polygenic risk scores and cognition in schizophrenia
AL Richards, AF Pardiñas, A Frizzati, KE Tansey, AJ Lynham, P Holmans, ...
Schizophrenia bulletin 46 (2), 336-344, 2020
1022020
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