Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation B Faustin, L Lartigue, JM Bruey, F Luciano, E Sergienko, B Bailly-Maitre, ... Molecular cell 25 (5), 713-724, 2007 | 885 | 2007 |
Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity W Song, J Chen, A Petrilli, G Liot, E Klinglmayr, Y Zhou, P Poquiz, J Tjong, ... Nature medicine 17 (3), 377-382, 2011 | 579 | 2011 |
The structural basis of actin filament branching by the Arp2/3 complex I Rouiller, XP Xu, KJ Amann, C Egile, S Nickell, D Nicastro, R Li, ... The Journal of cell biology 180 (5), 887, 2008 | 422 | 2008 |
Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy GL McLelland, T Goiran, W Yi, G Dorval, CX Chen, ND Lauinger, AI Krahn, ... Elife 7, e32866, 2018 | 332 | 2018 |
Conformational changes of the multifunction p97 AAA ATPase during its ATPase cycle I Rouiller, B DeLaBarre, AP May, WI Weis, AT Brunger, RA Milligan, ... Nature structural biology 9 (12), 950-957, 2002 | 253 | 2002 |
“Breathing” vesicles S Yu, T Azzam, I Rouiller, A Eisenberg Journal of the American Chemical Society 131 (30), 10557-10566, 2009 | 241 | 2009 |
Mechanistic differences in actin bundling activity of two mammalian formins, FRL1 and mDia2 ES Harris, I Rouiller, D Hanein, HN Higgs Journal of Biological Chemistry 281 (20), 14383-14392, 2006 | 214 | 2006 |
A major conformational change in p97 AAA ATPase upon ATP binding I Rouiller, VM Butel, M Latterich, RA Milligan, EM Wilson-Kubalek Molecular cell 6 (6), 1485-1490, 2000 | 182 | 2000 |
The Peptidisc, a simple method for stabilizing membrane proteins in detergent-free solution ML Carlson, JW Young, Z Zhao, L Fabre, D Jun, J Li, J Li, HS Dhupar, ... Elife 7, e34085, 2018 | 164 | 2018 |
Metal–nucleic acid cages H Yang, CK McLaughlin, FA Aldaye, GD Hamblin, AZ Rys, I Rouiller, ... Nature chemistry 1 (5), 390-396, 2009 | 158 | 2009 |
African swine fever virus is wrapped by the endoplasmic reticulum I Rouiller, SM Brookes, AD Hyatt, M Windsor, T Wileman Journal of virology 72 (3), 2373-2387, 1998 | 146 | 1998 |
Mechanism of filament nucleation and branch stability revealed by the structure of the Arp2/3 complex at actin branch junctions C Egile, I Rouiller, XP Xu, N Volkmann, R Li, D Hanein PLoS biology 3 (11), e383, 2005 | 134 | 2005 |
Hereditary inclusion body myopathy-linked p97/VCP mutations in the NH2 domain and the D1 ring modulate p97/VCP ATPase activity and D2 ring conformation D Halawani, AC LeBlanc, I Rouiller, SW Michnick, MJ Servant, M Latterich Molecular and cellular biology, 2009 | 129 | 2009 |
Gigantism in unique biogenic magnetite at the Paleocene–Eocene Thermal Maximum D Schumann, TD Raub, RE Kopp, JL Guerquin-Kern, TD Wu, I Rouiller, ... Proceedings of the National Academy of Sciences 105 (46), 17648-17653, 2008 | 101 | 2008 |
Structure–Function Profile of MmpL3, the Essential Mycolic Acid Transporter from Mycobacterium tuberculosis JM Belardinelli, A Yazidi, L Yang, L Fabre, W Li, B Jacques, SK Angala, ... ACS infectious diseases 2 (10), 702-713, 2016 | 98 | 2016 |
Effects of Arp2 and Arp3 nucleotide-binding pocket mutations on Arp2/3 complex function AC Martin, XP Xu, I Rouiller, M Kaksonen, Y Sun, L Belmont, N Volkmann, ... The Journal of cell biology 168 (2), 315, 2005 | 98 | 2005 |
Desulfovibrio magneticus RS-1 contains an iron- and phosphorus-rich organelle distinct from its bullet-shaped magnetosomes ME Byrne, DA Ball, JL Guerquin-Kern, I Rouiller, TD Wu, KH Downing, ... Proceedings of the National Academy of Sciences 107 (27), 12263-12268, 2010 | 97 | 2010 |
An asymmetric opening of HIV-1 envelope mediates antibody-dependent cellular cytotoxicity N Alsahafi, N Bakouche, M Kazemi, J Richard, S Ding, S Bhattacharyya, ... Cell host & microbe 25 (4), 578-587. e5, 2019 | 96 | 2019 |
Prepore to pore transition of a cholesterol-dependent cytolysin visualized by electron microscopy TX Dang, EM Hotze, I Rouiller, RK Tweten, EM Wilson-Kubalek Journal of structural biology 150 (1), 100-108, 2005 | 92 | 2005 |
Three‐dimensional reconstructions of Arp2/3 complex with bound nucleation promoting factors XP Xu, I Rouiller, BD Slaughter, C Egile, E Kim, JR Unruh, X Fan, ... The EMBO journal 31 (1), 236-247, 2012 | 91 | 2012 |