Kidney micro-organoids in suspension culture as a scalable source of human pluripotent stem cell-derived kidney cells SV Kumar, PX Er, KT Lawlor, A Motazedian, M Scurr, I Ghobrial, ... Development 146 (5), dev172361, 2019 | 122 | 2019 |
Characterization and neural differentiation of mouse embryonic and induced pluripotent stem cells on cadherin-based substrata A Haque, XS Yue, A Motazedian, Y Tagawa, T Akaike Biomaterials 33 (20), 5094-5106, 2012 | 75 | 2012 |
Multipotent RAG1+ progenitors emerge directly from haemogenic endothelium in human pluripotent stem cell-derived haematopoietic organoids A Motazedian, FF Bruveris, SV Kumar, JV Schiesser, T Chen, ES Ng, ... Nature cell biology 22 (1), 60-73, 2020 | 50 | 2020 |
Inhibition of METTL3 results in a cell-intrinsic interferon response that enhances antitumor immunity AA Guirguis, Y Ofir-Rosenfeld, K Knezevic, W Blackaby, D Hardick, ... Cancer Discovery 13 (10), 2228-2247, 2023 | 31 | 2023 |
GAPTrap: a simple expression system for pluripotent stem cells and their derivatives T Kao, T Labonne, JC Niclis, R Chaurasia, Z Lokmic, E Qian, FF Bruveris, ... Stem cell reports 7 (3), 518-526, 2016 | 29 | 2016 |
An engineered N-cadherin substrate for differentiation, survival, and selection of pluripotent stem cell-derived neural progenitors A Haque, N Adnan, A Motazedian, F Akter, S Hossain, K Kutsuzawa, ... PLoS One 10 (8), e0135170, 2015 | 27 | 2015 |
Pharmacologic reduction of mitochondrial iron triggers a noncanonical BAX/BAK-dependent cell death S Garciaz, AA Guirguis, S Müller, FC Brown, YC Chan, A Motazedian, ... Cancer Discovery 12 (3), 774-791, 2022 | 24 | 2022 |
Induced pluripotent stem cell macrophages present antigen to proinsulin-specific T cell receptors from donor-matched islet-infiltrating T cells in type 1 diabetes K Joshi, C Elso, A Motazedian, T Labonne, JV Schiesser, F Cameron, ... Diabetologia 62, 2245-2251, 2019 | 23 | 2019 |
Treatment-induced cell cycle kinetics dictate tumor response to chemotherapy RM Hallett, C Huang, A Motazedian, SA der Mauer, GR Pond, JA Hassell, ... Oncotarget 6 (9), 7040, 2015 | 23 | 2015 |
Human yolk sac-like haematopoiesis generates RUNX1-, GFI1- and/or GFI1B-dependent blood and SOX17-positive endothelium FF Bruveris, ES Ng, AR Leitoguinho, A Motazedian, K Vlahos, K Sourris, ... Development 147 (20), dev193037, 2020 | 20 | 2020 |
Generation of a heterozygous COL1A1 (c. 3969_3970insT) osteogenesis imperfecta mutation human iPSC line, MCRIi001-A-1, using CRISPR/Cas9 editing HH Far, YN Patria, A Motazedian, AG Elefanty, EG Stanley, SR Lamande, ... Stem Cell Research 37, 101449, 2019 | 19 | 2019 |
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes CE Sparbier, A Gillespie, J Gomez, N Kumari, A Motazedian, KL Chan, ... Nature cell biology 25 (2), 258-272, 2023 | 17 | 2023 |
Quantifying intrinsic and extrinsic control of single-cell fates in cancer and stem/progenitor cell pedigrees with competing risks analysis JA Cornwell, RM Hallett, SA der Mauer, A Motazedian, T Schroeder, ... Scientific reports 6 (1), 27100, 2016 | 16 | 2016 |
Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses KL Chan, J Gomez, C Cardinez, N Kumari, CE Sparbier, EYN Lam, ... Cancer Cell 40 (10), 1190-1206. e9, 2022 | 14 | 2022 |
The use of simultaneous reprogramming and gene correction to generate an osteogenesis imperfecta patient COL1A1 c. 3936 G> T iPSC line and an isogenic control iPSC line S Howden, HH Far, A Motazedian, AG Elefanty, EG Stanley, SR Lamandé, ... Stem Cell Research 38, 101453, 2019 | 11 | 2019 |
Auf der Mauer S, Pond GR, Hassell JA, Nordon RE and Draper JS: Treatment-induced cell cycle kinetics dictate tumor response to chemotherapy RM Hallett, C Huang, A Motazedian Oncotarget 6, 7040-7052, 2015 | 7 | 2015 |
MSL pushes genomic instability over the edge A Motazedian, MA Dawson Nature Cell Biology 23 (4), 295-296, 2021 | 3 | 2021 |
Efficient generation of human NOTCH ligand-expressing haemogenic endothelial cells as infrastructure for in vitro haematopoiesis and lymphopoiesis S Sun, A Motazedian, JY Li, K Wijanarko, JJ Zhu, K Tharmarajah, ... Nature Communications 15 (1), 7698, 2024 | | 2024 |
Long-term engrafting multilineage hematopoietic cells differentiated from human induced pluripotent stem cells ES Ng, G Sarila, JY Li, HS Edirisinghe, R Saxena, S Sun, FF Bruveris, ... Nature Biotechnology, 1-14, 2024 | | 2024 |
3135–DECIPHERING THE CELL-INTRINSIC MECHANISMS CONTROLLING CELL FATE AND OUTPUT OF HEMATOPOIETIC STEM AND PROGENITOR CELLS AT SINGLE CLONE RESOLUTION. A Motazedian, E Wainwright, E Lam, L Fei, D Vassiliadis, A Oshlack, ... Experimental Hematology 124, S117, 2023 | | 2023 |