Advances in antibody design KE Tiller, PM Tessier Annual review of biomedical engineering 17, 191-216, 2015 | 303 | 2015 |
Arginine mutations in antibody complementarity-determining regions display context-dependent affinity/specificity trade-offs KE Tiller, L Li, S Kumar, MC Julian, S Garde, PM Tessier Journal of Biological Chemistry 292 (40), 16638-16652, 2017 | 67 | 2017 |
Facile affinity maturation of antibody variable domains using natural diversity mutagenesis KE Tiller, R Chowdhury, T Li, SD Ludwig, S Sen, CD Maranas, PM Tessier Frontiers in Immunology 8, 2017 | 58 | 2017 |
Design and Optimization of Anti-amyloid Domain Antibodies Specific for β-Amyloid and Islet Amyloid Polypeptide CC Lee, MC Julian, KE Tiller, F Meng, SE DuConge, R Akter, DP Raleigh, ... Journal of Biological Chemistry 291 (6), 2858-2873, 2016 | 50 | 2016 |
Co-evolution of affinity and stability of grafted amyloid-motif domain antibodies MC Julian, CC Lee, KE Tiller, LA Rabia, EK Day, AJ Schick III, PM Tessier Protein Engineering, Design and Selection 28 (10), 339-350, 2015 | 40 | 2015 |
Conformational stability as a design target to control protein aggregation JA Costanzo, CJ O'brien, K Tiller, E Tamargo, AS Robinson, CJ Roberts, ... Protein Engineering, Design & Selection 27 (5), 157-167, 2014 | 34 | 2014 |
Computational Biology: Lifting the veil on amyloid drug design KE Tiller, PM Tessier Elife 2, e01089, 2013 | 6 | 2013 |