Second signals rescue B cells from activation-induced mitochondrial dysfunction and death M Akkaya, J Traba, AS Roesler, P Miozzo, B Akkaya, BP Theall, H Sohn, ... Nature immunology 19 (8), 871-884, 2018 | 220 | 2018 |
Toll-like receptor 9 antagonizes antibody affinity maturation M Akkaya, B Akkaya, AS Kim, P Miozzo, H Sohn, M Pena, AS Roesler, ... Nature immunology 19 (3), 255-266, 2018 | 74 | 2018 |
An optimized protocol to analyze glycolysis and mitochondrial respiration in lymphocytes J Traba, P Miozzo, B Akkaya, SK Pierce, M Akkaya JoVE (Journal of Visualized Experiments), e54918, 2016 | 61 | 2016 |
Increased mitochondrial biogenesis and reactive oxygen species production accompany prolonged CD4+ T cell activation B Akkaya, AS Roesler, P Miozzo, BP Theall, J Al Souz, MG Smelkinson, ... The Journal of Immunology 201 (11), 3294-3306, 2018 | 54 | 2018 |
B cells produce type 1 IFNs in response to the TLR9 agonist CpG-A conjugated to cationic lipids M Akkaya, B Akkaya, P Miozzo, M Rawat, M Pena, PW Sheehan, AS Kim, ... The Journal of Immunology 199 (3), 931-940, 2017 | 27 | 2017 |
A simple, versatile antibody-based barcoding method for flow cytometry B Akkaya, P Miozzo, AH Holstein, EM Shevach, SK Pierce, M Akkaya The Journal of Immunology 197 (5), 2027-2038, 2016 | 27 | 2016 |
T cell‐dependent antigen adjuvanted with DOTAP‐CpG‐B but not DOTAP‐CpG‐A induces robust germinal center responses and high affinity antibodies in mice M Akkaya, B Akkaya, PW Sheehan, P Miozzo, M Pena, CF Qi, ... European Journal of Immunology 47 (11), 1890-1899, 2017 | 17 | 2017 |
Prolonged activation in CD4+ T cells results in extensive mitochondrial remodeling despite the metabolic dominance of aerobic glycolysis B Akkaya, A Roesler, BP Theall, JA Al Souz, P Miozzo, J Traba, ... The Journal of Immunology 202 (1_Supplement), 128.6-128.6, 2019 | 1 | 2019 |
Immunization with a T cell-dependent protein antigen adjuvanted with DOTAP-CpG-B but not DOTAP-CpG-A induces robust germinal center responses and high affinity antibodies M Akkaya, B Akkaya, PW Sheehan, P Miozzo, M Pena, CF Qi, ... European journal of immunology 47 (11), 1890, 2017 | 1 | 2017 |
High-Resolution Multicolor Imaging of Mitochondria in Lymphocytes M Akkaya, P Miozzo, MG Smelkinson Confocal Microscopy: Methods and Protocols, 131-145, 2021 | | 2021 |
Antigen binding to B cells activates a metabolic program that in the absence of a second signal leads to mitochondrial dysfunction and cell death M Akkaya, AS Roesler, J Traba, P Miozzo, B Akkaya, BP Theall, H Sohn, ... The Journal of Immunology 200 (1_Supplement), 171.4-171.4, 2018 | | 2018 |
Toll-like receptor 9 signaling antagonizes B cell antigen capture, processing and presentation resulting in a failure to activate helper T cells M Akkaya, B Akkaya, AS Kim, P Miozzo, H Sohn, M Pena, AS Roesler, ... The Journal of Immunology 200 (1_Supplement), 107.1-107.1, 2018 | | 2018 |
A novel multicolor stimulated emission depletion (STED) microscopy strategy to visualize mitochondrial morphology in lymphocytes AS Roesler, P Miozzo, M Smelkinson, B Akkaya, J Brzostowski, J Kabat, ... The Journal of Immunology 200 (1_Supplement), 174.4-174.4, 2018 | | 2018 |
Application of super-resolution microscopy to the study of B and T lymphocyte mitochondria morphology and metabolism AS Roesler, P Miozzo, B Akkaya, M Smelkinson, J Brzostowski, J Kabat, ... The Journal of Immunology 198 (1_Supplement), 81.2-81.2, 2017 | | 2017 |
The Toll-like receptor ligand CpG-A induces type 1 interferons in B cells contrasting the proinflammatory inducing activity of CpG-B M Akkaya, B Akkaya, P Sheehan, P Miozzo, M Rawat, M Pena, AS Kim, ... The Journal of Immunology 198 (1_Supplement), 152.4-152.4, 2017 | | 2017 |
Toll-like receptor 9 signaling antagonizes antigen-specific B cell-helper T cell interactions M Akkaya, B Akkaya, AS Kim, P Miozzo, H Sohn, M Pena, J Skinner, ... The Journal of Immunology 198 (1_Supplement), 152.3-152.3, 2017 | | 2017 |
一种优化的协议分析和糖酵解线粒体呼吸的淋巴细胞 J Traba, P Miozzo, B Akkaya, SK Pierce, M Akkaya | | 2016 |
Toll-like receptor 9 signaling antagonizes the B cell receptor-dependent ability of B cells to process and present antigen to helper T cells. M Akkaya, AS Kim, P Miozzo, HW Sohn, B Akkaya, M Pena, SK Pierce The Journal of Immunology 196 (1_Supplement), 198.6-198.6, 2016 | | 2016 |
B cells have bifurcated Toll-like receptor signaling allowing both inflammatory cytokine and type 1 interferon responses. M Akkaya, M Rawat, B Akkaya, A Chaturvedi, M Pena, P Miozzo, AS Kim, ... The Journal of Immunology 196 (1_Supplement), 189.18-189.18, 2016 | | 2016 |
최적화된 프로토콜은 림프구에 해당 작용과 미토콘드리아 호흡을 분석하는 J Traba, P Miozzo, B Akkaya, SK Pierce, M Akkaya | | |