Pore-forming toxins induce macrophage necroptosis during acute bacterial pneumonia N González-Juarbe, RP Gilley, CA Hinojosa, KM Bradley, A Kamei, G Gao, ... PLoS pathogens 11 (12), e1005337, 2015 | 235 | 2015 |
NAD+ depletion triggers macrophage necroptosis, a cell death pathway exploited by Mycobacterium tuberculosis D Pajuelo, N Gonzalez-Juarbe, U Tak, J Sun, CJ Orihuela, M Niederweis Cell reports 24 (2), 429-440, 2018 | 167 | 2018 |
Severe pneumococcal pneumonia causes acute cardiac toxicity and subsequent cardiac remodeling LF Reyes, MI Restrepo, CA Hinojosa, NJ Soni, A Anzueto, BL Babu, ... American Journal of Respiratory and Critical Care Medicine 196 (5), 609-620, 2017 | 128 | 2017 |
Streptococcus pneumoniae biofilm formation is strain dependent, multifactorial, and associated with reduced invasiveness and immunoreactivity during colonization K Blanchette-Cain, CA Hinojosa, R Akula Suresh Babu, A Lizcano, ... MBio 4 (5), 10.1128/mbio. 00745-13, 2013 | 120 | 2013 |
Pore-forming toxin-mediated ion dysregulation leads to death receptor-independent necroptosis of lung epithelial cells during bacterial pneumonia N González-Juarbe, KM Bradley, AT Shenoy, RP Gilley, LF Reyes, ... Cell Death & Differentiation 24 (5), 917-928, 2017 | 102 | 2017 |
Streptococcus pneumoniae in the heart subvert the host response through biofilm-mediated resident macrophage killing AT Shenoy, T Brissac, RP Gilley, N Kumar, Y Wang, N Gonzalez-Juarbe, ... PLoS pathogens 13 (8), e1006582, 2017 | 70 | 2017 |
Infiltrated macrophages die of pneumolysin-mediated necroptosis following pneumococcal myocardial invasion RP Gilley, N González-Juarbe, AT Shenoy, LF Reyes, PH Dube, ... Infection and immunity 84 (5), 1457-1469, 2016 | 68 | 2016 |
Killing of Serratia marcescens biofilms with chloramphenicol C Ray, AT Shenoy, CJ Orihuela, N González-Juarbe Annals of clinical microbiology and antimicrobials 16, 1-6, 2017 | 56 | 2017 |
Bacterial pore-forming toxins promote the activation of caspases in parallel to necroptosis to enhance alarmin release and inflammation during pneumonia N Gonzalez-Juarbe, KM Bradley, AN Riegler, LF Reyes, T Brissac, ... Scientific reports 8 (1), 5846, 2018 | 43 | 2018 |
A non-human primate model of severe pneumococcal pneumonia LF Reyes, MI Restrepo, CA Hinojosa, NJ Soni, AT Shenoy, RP Gilley, ... PloS one 11 (11), e0166092, 2016 | 42 | 2016 |
Necroptotic cell death promotes adaptive immunity against colonizing pneumococci AN Riegler, T Brissac, N Gonzalez-Juarbe, CJ Orihuela Frontiers in Immunology 10, 615, 2019 | 41 | 2019 |
Requirement for Serratia marcescens cytolysin in a murine model of hemorrhagic pneumonia N González-Juarbe, CA Mares, CA Hinojosa, JL Medina, A Cantwell, ... Infection and immunity 83 (2), 614-624, 2015 | 40 | 2015 |
Influenza-induced oxidative stress sensitizes lung cells to bacterial-toxin-mediated necroptosis N Gonzalez-Juarbe, AN Riegler, AS Jureka, RP Gilley, JD Brand, ... Cell reports 32 (8), 2020 | 36 | 2020 |
Streptococcus pneumoniae binds to host GAPDH on dying lung epithelial cells worsening secondary infection following influenza SS Park, N Gonzalez-Juarbe, AN Riegler, H Im, Y Hale, MP Platt, ... Cell reports 35 (11), 2021 | 28 | 2021 |
NAD hydrolysis by the tuberculosis necrotizing toxin induces lethal oxidative stress in macrophages D Pajuelo, N Gonzalez‐Juarbe, M Niederweis Cellular microbiology 22 (1), e13115, 2020 | 28 | 2020 |
Omega-3 fatty acids in contrast to omega-6 protect against pneumococcal pneumonia CA Hinojosa, N Gonzalez-Juarbe, MM Rahman, G Fernandes, ... Microbial pathogenesis 141, 103979, 2020 | 23 | 2020 |
Kinetic multi-omic analysis of responses to SARS-CoV-2 infection in a model of severe COVID-19 AM Cantwell, H Singh, M Platt, Y Yu, YH Lin, Y Ikeno, G Hubbard, Y Xiang, ... Journal of virology 95 (20), 10.1128/jvi. 01010-21, 2021 | 21 | 2021 |
Streptococcus pneumoniae binds to host lactate dehydrogenase via PspA and PspC to enhance virulence SS Park, N Gonzalez-Juarbe, E Martínez, JY Hale, YH Lin, JT Huffines, ... MBio 12 (3), 10.1128/mbio. 00673-21, 2021 | 21 | 2021 |
Global proteome and phosphoproteome characterization of sepsis-induced kidney injury YH Lin, MP Platt, H Fu, Y Gui, Y Wang, N Gonzalez-Juarbe, D Zhou, Y Yu Molecular & Cellular Proteomics 19 (12), 2030-2047, 2020 | 21 | 2020 |
Inhibition of necroptosis to prevent long-term cardiac damage during pneumococcal pneumonia and invasive disease SM Beno, AN Riegler, RP Gilley, T Brissac, Y Wang, KL Kruckow, ... The Journal of infectious diseases 222 (11), 1882-1893, 2020 | 19 | 2020 |