Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract J Zhang, ME Walker, KZ Sanidad, H Zhang, Y Liang, E Zhao, ... Nature communications 13 (1), 136, 2022 | 58 | 2022 |
Cooperativity between verapamil and ATP bound to the efflux transporter P-glycoprotein KV Ledwitch, ME Gibbs, RW Barnes, AG Roberts Biochemical pharmacology 118, 96-108, 2016 | 53 | 2016 |
Bile salt hydrolases shape the bile acid landscape and restrict Clostridioides difficile growth in the murine gut MH Foley, ME Walker, AK Stewart, S O’Flaherty, EC Gentry, S Patel, ... Nature microbiology 8 (4), 611-628, 2023 | 48 | 2023 |
Mechanisms and the clinical relevance of complex drug–drug interactions AG Roberts, ME Gibbs Clinical pharmacology: advances and applications, 123-134, 2018 | 46 | 2018 |
Structural insights into endobiotic reactivation by human gut microbiome-encoded sulfatases SM Ervin, JB Simpson, ME Gibbs, BC Creekmore, L Lim, WG Walton, ... Biochemistry 59 (40), 3939-3950, 2020 | 41 | 2020 |
Ubiquitin chain-elongating enzyme UBE2S activates the RING E3 ligase APC/C for substrate priming RC Martinez-Chacin, T Bodrug, DL Bolhuis, KM Kedziora, T Bonacci, ... Nature structural & molecular biology 27 (6), 550-560, 2020 | 28 | 2020 |
A structural metagenomics pipeline for examining the gut microbiome ME Walker, JB Simpson, MR Redinbo Current opinion in structural biology 75, 102416, 2022 | 16 | 2022 |
A conformationally gated model of methadone and loperamide transport by P-glycoprotein ME Gibbs, LA Wilt, KV Ledwitch, AG Roberts Journal of pharmaceutical sciences 107 (7), 1937-1947, 2018 | 13 | 2018 |
Bile salt hydrolases shape the bile acid landscape and restrict Clostridioides difficile growth in the murine gut. Nat Microbiol 8: 611–628 MH Foley, ME Walker, AK Stewart, S O’Flaherty, EC Gentry, S Patel, ... | 5 | 2023 |
Crystal structure of UDP-glucose pyrophosphorylase from Yersinia pestis, a potential therapeutic target against plague ME Gibbs, GT Lountos, R Gumpena, DS Waugh Acta Crystallographica Section F: Structural Biology Communications 75 (9 …, 2019 | 5 | 2019 |
Distinct bile salt hydrolase substrate preferences dictate C. difficile pathogenesis MH Foley, ME Walker, AK Stewart, S O’Flaherty, EC Gentry, G Allen, ... | 4 | 2022 |
Gut microbial β-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics JB Simpson, ME Walker, JJ Sekela, SM Ivey, PB Jariwala, CM Storch, ... Cell Host & Microbe 32 (6), 925-944. e10, 2024 | 1 | 2024 |
Probing the structural basis of P‐glycoprotein transport of μ‐opioid receptor agonists: methadone and loperamide ME Gibbs, K Ledwitch, A Roberts The FASEB Journal 31, 950.6-950.6, 2017 | 1 | 2017 |
Structural Basis for Methine Excision by a Heme Oxygenase-like Enzyme WC Simke, ME Walker, LA Calderone, AT Putz, JB Patteson, CN Vitro, ... ACS Central Science, 2024 | | 2024 |
Abstract 2470 A copper-containing antibiotic produced by Pseudomonas B Li, W Simke, M Walker, L Calderone, A Putz, J Patteson, M Redinbo, ... Journal of Biological Chemistry 300 (3), 2024 | | 2024 |
Structural Mining of Gut Metagenomes Pinpoints Therapeutically Relevant Microbial Enzymes J Simpson, M Redinbo, M Walker ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 78, A153-A153, 2022 | | 2022 |
Bile salt hydrolases shape the bile acid landscape and restrict C. difficile MH Foley, ME Walker, AK Stewart, S O’Flaherty, EC Gentry, G Allen, ... bioRxiv, 2022.03. 24.485529, 2022 | | 2022 |
Bile salt hydrolase substrate preference directs C. difficile infection M Walker, M Redinbo Foundations of Crystallography 78, a12, 2022 | | 2022 |
Probing the Structural Basis of Triclosan-Glucuronide Processing by Flavin Mononucleotide-Binding β-Glucuronidases V Beaty | | 2021 |
Pedestal confinement and stability in JET-ILW ELMy H-modes S Saarelma, FJ Casson, C Challis, E De La Luna, L Frassinetti, C Giroud, ... NUCLEAR FUSION, 2015 | | 2015 |