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Manu Vanaerschot
Manu Vanaerschot
Roche Diagnostics, Infectious Diseases
在 roche.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance
T Downing, H Imamura, S Decuypere, TG Clark, GH Coombs, JA Cotton, ...
Genome research 21 (12), 2143-2156, 2011
4982011
Increasing failure of miltefosine in the treatment of Kala-azar in Nepal and the potential role of parasite drug resistance, reinfection, or noncompliance
S Rijal, B Ostyn, S Uranw, K Rai, NR Bhattarai, TPC Dorlo, JH Beijnen, ...
Clinical Infectious Diseases 56 (11), 1530-1538, 2013
3612013
Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics
AN Cowell, ES Istvan, AK Lukens, MG Gomez-Lorenzo, M Vanaerschot, ...
Science 359 (6372), 191-199, 2018
2252018
Evolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinent
H Imamura, T Downing, F Van den Broeck, MJ Sanders, S Rijal, S Sundar, ...
Elife 5, e12613, 2016
1672016
Modulation of Aneuploidy in Leishmania donovani during Adaptation to Different In Vitro and In Vivo Environments and Its Impact on Gene Expression
F Dumetz, H Imamura, M Sanders, V Seblova, J Myskova, P Pescher, ...
MBio 8 (3), 10.1128/mbio. 00599-17, 2017
1592017
Evaluation of normalization methods to pave the way towards large-scale LC-MS-based metabolomics profiling experiments
BA Ejigu, D Valkenborg, G Baggerman, M Vanaerschot, E Witters, ...
Omics: a journal of integrative biology 17 (9), 473-485, 2013
1292013
Open-source discovery of chemical leads for next-generation chemoprotective antimalarials
Y Antonova-Koch, S Meister, M Abraham, MR Luth, S Ottilie, AK Lukens, ...
Science 362 (6419), eaat9446, 2018
1122018
Molecular Mechanisms of Drug Resistance in Natural Leishmania Populations Vary with Genetic Background
S Decuypere, M Vanaerschot, K Brunker, H Imamura, S Müller, B Khanal, ...
PLoS neglected tropical diseases 6 (2), e1514, 2012
1032012
Treatment failure in leishmaniasis: drug-resistance or another (epi-) phenotype?
M Vanaerschot, F Dumetz, S Roy, A Ponte-Sucre, J Arevalo, JC Dujardin
Expert review of anti-infective therapy 12 (8), 937-946, 2014
892014
Antileishmanial Activity of a Series of N2,N4-Disubstituted Quinazoline-2,4-diamines
KS Van Horn, X Zhu, T Pandharkar, S Yang, B Vesely, M Vanaerschot, ...
Journal of medicinal chemistry 57 (12), 5141-5156, 2014
882014
Relapse after treatment with miltefosine for visceral leishmaniasis is associated with increased infectivity of the infecting Leishmania donovani strain
K Rai, B Cuypers, NR Bhattarai, S Uranw, M Berg, B Ostyn, JC Dujardin, ...
MBio 4 (5), 10.1128/mbio. 00611-13, 2013
822013
Linking in vitro and in vivo survival of clinical Leishmania donovani strains
M Vanaerschot, I Maes, M Ouakad, V Adaui, L Maes, S De Doncker, ...
PLoS One 5 (8), e12211, 2010
782010
Detection of Leptomonas sp. parasites in clinical isolates of Kala-azar patients from India
P Srivastava, VK Prajapati, M Vanaerschot, G Van der Auwera, ...
Infection, Genetics and Evolution 10 (7), 1145-1150, 2010
702010
Identification of a polymorphism in the N gene of SARS-CoV-2 that adversely impacts detection by reverse transcription-PCR
M Vanaerschot, SA Mann, JT Webber, J Kamm, SM Bell, J Bell, SN Hong, ...
Journal of Clinical Microbiology 59 (1), 10.1128/jcm. 02369-20, 2020
682020
Combining stage specificity and metabolomic profiling to advance antimalarial drug discovery
JM Murithi, ES Owen, ES Istvan, MCS Lee, S Ottilie, K Chibale, ...
Cell chemical biology 27 (2), 158-171. e3, 2020
662020
UCT943, a next-generation Plasmodium falciparum PI4K inhibitor preclinical candidate for the treatment of malaria
C Brunschwig, N Lawrence, D Taylor, E Abay, M Njoroge, GS Basarab, ...
Antimicrobial agents and chemotherapy 62 (9), 10.1128/aac. 00012-18, 2018
662018
Treatment of Visceral Leishmaniasis: Model-Based Analyses on the Spread of Antimony-Resistant L. donovani in Bihar, India
A Stauch, HP Duerr, JC Dujardin, M Vanaerschot, S Sundar, M Eichner
PLoS neglected tropical diseases 6 (12), e1973, 2012
662012
LC-MS metabolomics from study design to data-analysis–using a versatile pathogen as a test case
M Berg, M Vanaerschot, A Jankevics, B Cuypers, R Breitling, JC Dujardin
Computational and structural biotechnology journal 4 (5), e201301002, 2013
652013
Genome-wide SNP and microsatellite variation illuminate population-level epidemiology in the Leishmania donovani species complex
T Downing, O Stark, M Vanaerschot, H Imamura, M Sanders, ...
Infection, Genetics and Evolution 12 (1), 149-159, 2012
652012
Increased metacyclogenesis of antimony-resistant Leishmania donovani clinical lines
M Ouakad, M Vanaerschot, S Rijal, S Sundar, N Speybroeck, L Kestens, ...
Parasitology 138 (11), 1392-1399, 2011
652011
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