Genetic and epigenetic fine mapping of causal autoimmune disease variants KKH Farh, A Marson, J Zhu, M Kleinewietfeld, WJ Housley, S Beik, ... Nature 518 (7539), 337-343, 2015 | 1977 | 2015 |
Origins of tumor-associated macrophages and neutrophils V Cortez-Retamozo, M Etzrodt, A Newton, PJ Rauch, A Chudnovskiy, ... Proceedings of the National Academy of Sciences 109 (7), 2491-2496, 2012 | 715 | 2012 |
A genetic variant associated with five vascular diseases is a distal regulator of endothelin-1 gene expression RM Gupta, J Hadaya, A Trehan, SM Zekavat, C Roselli, D Klarin, ... Cell 170 (3), 522-533. e15, 2017 | 419 | 2017 |
An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma Y Drier, MJ Cotton, KE Williamson, SM Gillespie, RJH Ryan, MJ Kluk, ... Nature genetics 48 (3), 265-272, 2016 | 265 | 2016 |
Angiotensin II drives the production of tumor-promoting macrophages V Cortez-Retamozo, M Etzrodt, A Newton, R Ryan, F Pucci, SW Sio, ... Immunity 38 (2), 296-308, 2013 | 208 | 2013 |
EZH2 codon 641 mutations are common in BCL2-rearranged germinal center B cell lymphomas RJH Ryan, M Nitta, D Borger, LR Zukerberg, JA Ferry, NL Harris, ... PloS one 6 (12), e28585, 2011 | 142 | 2011 |
A multiplexed system for quantitative comparisons of chromatin landscapes P van Galen, AD Viny, O Ram, RJH Ryan, MJ Cotton, L Donohue, ... Molecular cell 61 (1), 170-180, 2016 | 130 | 2016 |
Detection of enhancer-associated rearrangements reveals mechanisms of oncogene dysregulation in B-cell lymphoma RJH Ryan, Y Drier, H Whitton, MJ Cotton, J Kaur, R Issner, S Gillespie, ... Cancer discovery 5 (10), 1058-1071, 2015 | 129 | 2015 |
IRF6 is a mediator of Notch pro‐differentiation and tumour suppressive function in keratinocytes G Restivo, BC Nguyen, P Dziunycz, E Ristorcelli, RJH Ryan, ÖY Özuysal, ... The EMBO journal 30 (22), 4571-4585, 2011 | 127 | 2011 |
Squamous Cell Carcinoma Related Oncogene/DCUN1D1 Is Highly Conserved and Activated by Amplification in Squamous Cell Carcinomas I Sarkaria, P O-charoenrat, SG Talbot, PG Reddy, I Ngai, E Maghami, ... Cancer research 66 (19), 9437-9444, 2006 | 105 | 2006 |
AB cell regulome links notch to downstream oncogenic pathways in small B cell lymphomas RJH Ryan, J Petrovic, DM Rausch, Y Zhou, CA Lareau, MJ Kluk, ... Cell reports 21 (3), 784-797, 2017 | 73 | 2017 |
Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue with amyloid deposition: a clinicopathologic case series RJH Ryan, JM Sloan, AB Collins, J Mansouri, NS Raje, LR Zukerberg, ... American Journal of Clinical Pathology 137 (1), 51-64, 2012 | 71 | 2012 |
Genetic events that shape the cancer epigenome RJH Ryan, BE Bernstein Science 336 (6088), 1513-1514, 2012 | 63 | 2012 |
Mast cell sarcoma: a rare and potentially under-recognized diagnostic entity with specific therapeutic implications RJH Ryan, C Akin, M Castells, M Wills, MK Selig, GP Nielsen, JA Ferry, ... Modern Pathology 26 (4), 533-543, 2013 | 59 | 2013 |
Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain S Shukla, W Ying, F Gray, Y Yao, ML Simes, Q Zhao, H Miao, HJ Cho, ... Nature chemical biology 17 (7), 784-793, 2021 | 39 | 2021 |
Perspectives on ENCODE F Abascal, R Acosta, NJ Addleman, J Adrian, V Afzal, B Aken, JA Akiyama Nature 583 (7818), 693-699, 2020 | 25 | 2020 |
Squamous cell carcinoma-related oncogene (SCCRO) family members regulate cell growth and proliferation through their cooperative and antagonistic effects on cullin neddylation W Fu, J Sun, G Huang, JC Liu, A Kaufman, RJH Ryan, SY Ramanathan, ... Journal of Biological Chemistry 291 (12), 6200-6217, 2016 | 22 | 2016 |
EWS:: FLI1 and HOXD13 control tumor cell plasticity in Ewing sarcoma AA Apfelbaum, F Wu, AG Hawkins, B Magnuson, JA Jiménez, SD Taylor, ... Clinical Cancer Research 28 (20), 4466-4478, 2022 | 16 | 2022 |
Combinatorial ETS1-dependent control of oncogenic NOTCH1 enhancers in T-cell leukemia AC McCarter, G Della Gatta, A Melnick, E Kim, C Sha, Q Wang, ... Blood cancer discovery 1 (2), 178-197, 2020 | 16 | 2020 |
ETV6 Deficiency Unlocks ERG-Dependent Microsatellite Enhancers to Drive Aberrant Gene Activation in B-Lymphoblastic Leukemia R Kodgule, JW Goldman, AC Monovich, T Saari, AR Aguilar, CN Hall, ... Blood Cancer Discovery 4 (1), 34-53, 2023 | 12 | 2023 |