| Biology and applications of CRISPR systems: harnessing nature’s toolbox for genome engineering AV Wright, JK Nuñez, JA Doudna Cell 164 (1), 29-44, 2016 | 1195 | 2016 |
| Cas1–Cas2 complex formation mediates spacer acquisition during CRISPR–Cas adaptive immunity JK Nuñez, PJ Kranzusch, J Noeske, AV Wright, CW Davies, JA Doudna Nature structural & molecular biology 21 (6), 528-534, 2014 | 583 | 2014 |
| Rational design of a split-Cas9 enzyme complex AV Wright, SH Sternberg, DW Taylor, BT Staahl, JA Bardales, JE Kornfeld, ... Proceedings of the National Academy of Sciences 112 (10), 2984-2989, 2015 | 379 | 2015 |
| Structures of the CRISPR genome integration complex AV Wright, JJ Liu, GJ Knott, KW Doxzen, E Nogales, JA Doudna Science 357 (6356), 1113-1118, 2017 | 149 | 2017 |
| Protecting genome integrity during CRISPR immune adaptation AV Wright, JA Doudna Nature structural & molecular biology 23 (10), 876-883, 2016 | 118 | 2016 |
| Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling IE Ivanov, AV Wright, JC Cofsky, KDP Aris, JA Doudna, Z Bryant Proceedings of the National Academy of Sciences 117 (11), 5853-5860, 2020 | 81 | 2020 |
| Mutations in Cas9 enhance the rate of acquisition of viral spacer sequences during the CRISPR-Cas immune response R Heler, AV Wright, M Vucelja, D Bikard, JA Doudna, LA Marraffini Molecular cell 65 (1), 168-175, 2017 | 56 | 2017 |
| A functional mini-integrase in a two-protein type VC CRISPR system AV Wright, JY Wang, D Burstein, LB Harrington, D Paez-Espino, ... Molecular cell 73 (4), 727-737. e3, 2019 | 31 | 2019 |
| Spacer acquisition rates determine the immunological diversity of the type II CRISPR-Cas immune response R Heler, AV Wright, M Vucelja, JA Doudna, LA Marraffini Cell host & microbe 25 (2), 242-249. e3, 2019 | 24 | 2019 |
| Compositions and methods for the targeting of pcsk9 J Fernandes, S Higgins, S Denny, R White, EJM Charles, A Wright, ... US Patent App. 18/516,840, 2024 | | 2024 |
| Compositions and methods for the targeting of pcsk9 J Fernandes, S Higgins, S Denny, R White, EJM Charles, A Wright, ... US Patent App. 18/516,722, 2024 | | 2024 |
| Aav vectors for gene editing M Mohr, K Baney, A Sidore, C Fortuny, A Maroof, A Wright, BT Staahl, ... US Patent App. 18/266,076, 2024 | | 2024 |
| Single-molecule analysis of DNA interrogation by Cas9 and Cas12a on supercoiled DNA KDP Aris, J Cofsky, AV Wright, IE Ivanov, A Balaji, JA Doudna, Z Bryant Biophysical Journal 121 (3), 288a, 2022 | | 2022 |
| Heterodimeric Cas9 and methods of use thereof SH Sternberg, JA Doudna, AV Wright US Patent 11,208,638, 2021 | | 2021 |
| Mechanisms of CRISPR-Cas Immune Adaptation AV Wright University of California, Berkeley, 2018 | | 2018 |
| Keeping CRISPR under control: how bacteria fight viruses without harming themselves AV Wright Nature 1, 14, 2017 | | 2017 |
| Heterodimeric cas9 and methods of use thereof SH Sternberg, JA Doudna, AV WRIGHT | | 2016 |
