| Structural basis of Smoothened regulation by its extracellular domains EFX Byrne, R Sircar, PS Miller, G Hedger, G Luchetti, S Nachtergaele, ... Nature 535 (7613), 517-522, 2016 | 354 | 2016 |
| Cholesterol activates the G-protein coupled receptor Smoothened to promote Hedgehog signaling G Luchetti, R Sircar, JH Kong, S Nachtergaele, A Sagner, EFX Byrne, ... Elife 5, e20304, 2016 | 229 | 2016 |
| G protein–coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog GV Pusapati, JH Kong, BB Patel, M Gouti, A Sagner, R Sircar, G Luchetti, ... Science Signaling 11 (516), eaao5749, 2018 | 63 | 2018 |
| Co-folding of a FliF-FliG split domain forms the basis of the MS: C ring interface within the bacterial flagellar motor MJ Lynch, R Levenson, EA Kim, R Sircar, DF Blair, FW Dahlquist, ... Structure 25 (2), 317-328, 2017 | 61 | 2017 |
| Architecture of the soluble receptor Aer2 indicates an in-line mechanism for PAS and HAMP domain signaling MV Airola, D Huh, N Sukomon, J Widom, R Sircar, PP Borbat, JH Freed, ... Journal of molecular biology 425 (5), 886-901, 2013 | 59 | 2013 |
| Structure and activity of the flagellar rotor protein FliY: a member of the CheC phosphatase family R Sircar, AR Greenswag, AM Bilwes, G Gonzalez-Bonet, BR Crane Journal of Biological Chemistry 288 (19), 13493-13502, 2013 | 50 | 2013 |
| Assembly states of FliM and FliG within the flagellar switch complex R Sircar, PP Borbat, MJ Lynch, J Bhatnagar, MS Beyersdorf, CJ Halkides, ... Journal of molecular biology 427 (4), 867-886, 2015 | 46 | 2015 |
| Patched 1 reduces the accessibility of cholesterol in the outer leaflet of membranes M Kinnebrew, G Luchetti, R Sircar, S Frigui, LV Viti, T Naito, F Beckert, ... Elife 10, e70504, 2021 | 38 | 2021 |
| Self-association of the histidine kinase CheA as studied by pulsed dipolar ESR spectroscopy J Bhatnagar, R Sircar, PP Borbat, JH Freed, BR Crane Biophysical journal 102 (9), 2192-2201, 2012 | 22 | 2012 |
| Patched 1 regulates Smoothened by controlling sterol binding to its extracellular cysteine-rich domain M Kinnebrew, RE Woolley, TB Ansell, EFX Byrne, S Frigui, G Luchetti, ... Science Advances 8 (22), eabm5563, 2022 | 21 | 2022 |
| Bile acid biosynthesis in Smith-Lemli-Opitz syndrome bypassing cholesterol: Potential importance of pathway intermediates J Abdel-Khalik, T Hearn, AL Dickson, PJ Crick, E Yutuc, K Austin-Muttitt, ... The Journal of steroid biochemistry and molecular biology 206, 105794, 2021 | 17 | 2021 |
| Bile acid biosynthesis avoiding cholesterol WJ Griffiths, J Abdel-Khalik, PJ Crick, E Yutuc, M Ogundare, BW Bigger, ... bioRxiv, 385419, 2018 | 2 | 2018 |
| Production, characterization, and assessment of a stable analog of the response regulator CheY‐phosphate from Thermotoga maritima MS Beyersdorf, R Sircar, DB Lookadoo, CJ Bottone, MJ Lynch, BR Crane, ... Protein Science 26 (8), 1547-1554, 2017 | 2 | 2017 |
| Structural basis for Smoothened regulation by its extracellular domains C Siebold, E Byrne, P Miller, M Sansom, G Hedger, S Newstead, R Sircar, ... Nature 535, 2016 | | 2016 |
| Architecture Of The Bacterial Flagellar Rotor Elucidated With X-Ray Crystallography And Pulsed Dipolar Esr Spectroscopy R Sircar | | 2013 |
| 2SA-02 Architecture of the Flagellar Switch Complex (2SA Invited symposium from abroad: Forefront of biophysics, Symposium, The 50th Annual Meeting of the Biophysical Society … BR Crane, R Sircar, G Gonzalez-Bonet, K Paul, D Blair Seibutsu Butsuri 52 (supplement), S9, 2012 | | 2012 |
| Full wwPDB X-ray Structure Validation Report i○ MJ Lynch, R Levenson, EA Kim, R Sircar, DF Blair | | |
