The prognostic role of macrophage polarization in the colorectal cancer microenvironment JP Väyrynen, K Haruki, MC Lau, SA Väyrynen, R Zhong, A Dias Costa, ... Cancer immunology research 9 (1), 8-19, 2021 | 142 | 2021 |
Neoadjuvant selicrelumab, an agonist CD40 antibody, induces changes in the tumor microenvironment in patients with resectable pancreatic cancer KT Byrne, CB Betts, R Mick, S Sivagnanam, DL Bajor, DA Laheru, ... Clinical Cancer Research 27 (16), 4574-4586, 2021 | 137 | 2021 |
Leukocyte heterogeneity in pancreatic ductal adenocarcinoma: phenotypic and spatial features associated with clinical outcome SM Liudahl, CB Betts, S Sivagnanam, V Morales-Oyarvide, A Da Silva, ... Cancer discovery 11 (8), 2014-2031, 2021 | 118 | 2021 |
Composition, spatial characteristics, and prognostic significance of myeloid cell infiltration in pancreatic cancer SA Väyrynen, J Zhang, C Yuan, JP Väyrynen, A Dias Costa, H Williams, ... Clinical Cancer Research 27 (4), 1069-1081, 2021 | 115 | 2021 |
Association of Fusobacterium nucleatum with Specific T-cell Subsets in the Colorectal Carcinoma Microenvironment J Borowsky, K Haruki, MC Lau, A Dias Costa, JP Väyrynen, T Ugai, ... Clinical Cancer Research 27 (10), 2816-2826, 2021 | 70 | 2021 |
Prognostic significance of immune cell populations identified by machine learning in colorectal cancer using routine hematoxylin and eosin–stained sections JP Väyrynen, MC Lau, K Haruki, SA Väyrynen, A Dias Costa, J Borowsky, ... Clinical Cancer Research 26 (16), 4326-4338, 2020 | 55 | 2020 |
Spatially resolved single-cell assessment of pancreatic cancer expression subtypes reveals co-expressor phenotypes and extensive intratumoral heterogeneity HL Williams, A Dias Costa, J Zhang, S Raghavan, PS Winter, KS Kapner, ... Cancer research 83 (3), 441-455, 2023 | 54 | 2023 |
Neoadjuvant chemotherapy is associated with altered immune cell infiltration and an anti-tumorigenic microenvironment in resected pancreatic cancer A Dias Costa, SA Väyrynen, A Chawla, J Zhang, JP Väyrynen, MC Lau, ... Clinical Cancer Research 28 (23), 5167-5179, 2022 | 49 | 2022 |
Spatial organization and prognostic significance of NK and NKT-like cells via multimarker analysis of the colorectal cancer microenvironment JP Väyrynen, K Haruki, MC Lau, SA Väyrynen, T Ugai, N Akimoto, ... Cancer immunology research 10 (2), 215-227, 2022 | 37 | 2022 |
Immune cell profiles in the tumor microenvironment of early-onset, intermediate-onset, and later-onset colorectal cancer T Ugai, JP Väyrynen, MC Lau, J Borowsky, N Akimoto, SA Väyrynen, ... Cancer Immunology, Immunotherapy, 1-10, 2022 | 35 | 2022 |
Prognostic significance of myeloid immune cells and their spatial distribution in the colorectal cancer microenvironment JP Väyrynen, K Haruki, SA Väyrynen, MC Lau, AD Costa, J Borowsky, ... Journal for Immunotherapy of Cancer 9 (4), 2021 | 26 | 2021 |
An integrated analysis of lymphocytic reaction, tumour molecular characteristics and patient survival in colorectal cancer K Haruki, K Kosumi, P Li, K Arima, JP Väyrynen, MC Lau, TS Twombly, ... British Journal of Cancer 122 (9), 1367-1377, 2020 | 25 | 2020 |
Smoking and incidence of colorectal cancer subclassified by tumor-associated macrophage infiltrates T Ugai, JP Väyrynen, K Haruki, N Akimoto, MC Lau, R Zhong, J Kishikawa, ... JNCI: Journal of the National Cancer Institute 114 (1), 68-77, 2022 | 23 | 2022 |
Insulin-like growth factor-1 receptor expression and disease recurrence and survival in patients with resected pancreatic ductal adenocarcinoma C Du, A da Silva, V Morales-Oyarvide, A Dias Costa, MM Kozak, ... Cancer Epidemiology, Biomarkers & Prevention 29 (8), 1586-1595, 2020 | 15 | 2020 |
Randomized multicenter phase Ib/II study of neoadjuvant chemoradiation therapy (CRT) alone or in combination with pembrolizumab in patients with resectable or borderline … OE Rahma, MHG Katz, BM Wolpin, A Dias-Costa, J Nowak, SJ Rodig, ... Journal of Clinical Oncology 39 (15_suppl), 4128-4128, 2021 | 13 | 2021 |
PD-1 Blockade Induces Reactivation of Nonproductive T-Cell Responses Characterized by NF-κB Signaling in Patients with Pancreatic Cancer LR Ali, PJ Lenehan, V Cardot-Ruffino, A Dias Costa, MHG Katz, TW Bauer, ... Clinical Cancer Research 30 (3), 542-553, 2024 | 8 | 2024 |
Bayesian risk prediction model for colorectal cancer mortality through integration of clinicopathologic and genomic data M Zhao, MC Lau, K Haruki, JP Väyrynen, C Gurjao, SA Väyrynen, ... NPJ Precision Oncology 7 (1), 57, 2023 | 8 | 2023 |
The prognostic role of macrophage polarization in the colorectal cancer microenvironment. Cancer Immunol Res, 9: 8–19 JP Väyrynen, K Haruki, MC Lau, SA Väyrynen, R Zhong, A Dias Costa, ... | 8 | 2021 |
Machine learning links T-cell function and spatial localization to neoadjuvant immunotherapy and clinical outcome in pancreatic cancer KE Blise, S Sivagnanam, CB Betts, K Betre, N Kirchberger, BJ Tate, ... Cancer Immunology Research 12 (5), 544-558, 2024 | 6 | 2024 |
960 Randomized multicenter study of neoadjuvant chemoradiation therapy (CRT) alone or in combination with pembrolizumab in patients with resectable or borderline resectable … O Rahma, M Katz, T Bauer, B Wolpin, CC Stucky, T Bekaii-Saab, R Elias, ... Journal for ImmunoTherapy of Cancer 9 (Suppl 2), A1010-A1010, 2021 | 3 | 2021 |