| SARS-CoV-2 reverse genetics reveals a variable infection gradient in the respiratory tract YJ Hou, K Okuda, CE Edwards, DR Martinez, T Asakura, KH Dinnon, ... Cell 182 (2), 429-446. e14, 2020 | 1504 | 2020 |
| SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness KS Corbett, DK Edwards, SR Leist, OM Abiona, S Boyoglu-Barnum, ... Nature 586 (7830), 567-571, 2020 | 1472 | 2020 |
| An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice TP Sheahan, AC Sims, S Zhou, RL Graham, AJ Pruijssers, ML Agostini, ... Science translational medicine 12 (541), eabb5883, 2020 | 1114 | 2020 |
| SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo YJ Hou, S Chiba, P Halfmann, C Ehre, M Kuroda, KH Dinnon III, SR Leist, ... Science 370 (6523), 1464-1468, 2020 | 955 | 2020 |
| A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures KH Dinnon III, SR Leist, A Schäfer, CE Edwards, DR Martinez, ... Nature 586 (7830), 560-566, 2020 | 667 | 2020 |
| Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase AJ Brown, JJ Won, RL Graham, KH Dinnon III, AC Sims, JY Feng, T Cihlar, ... Antiviral research 169, 104541, 2019 | 569 | 2019 |
| A mouse-adapted SARS-CoV-2 induces acute lung injury and mortality in standard laboratory mice SR Leist, KH Dinnon, A Schäfer, VT Longping, K Okuda, YJ Hou, A West, ... Cell 183 (4), 1070-1085. e12, 2020 | 505 | 2020 |
| Remdesivir inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice AJ Pruijssers, AS George, A Schäfer, SR Leist, LE Gralinksi, KH Dinnon, ... Cell reports 32 (3), 2020 | 495 | 2020 |
| Elicitation of potent neutralizing antibody responses by designed protein nanoparticle vaccines for SARS-CoV-2 AC Walls, B Fiala, A Schäfer, S Wrenn, MN Pham, M Murphy, ... Cell 183 (5), 1367-1382. e17, 2020 | 453 | 2020 |
| SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801 A Wahl, LE Gralinski, CE Johnson, W Yao, M Kovarova, KH Dinnon III, ... Nature 591 (7850), 451-457, 2021 | 390 | 2021 |
| Further evidence for bats as the evolutionary source of Middle East respiratory syndrome coronavirus SJ Anthony, K Gilardi, VD Menachery, T Goldstein, B Ssebide, R Mbabazi, ... MBio 8 (2), 10.1128/mbio. 00373-17, 2017 | 278* | 2017 |
| An immunocompetent mouse model of Zika virus infection MJ Gorman, EA Caine, K Zaitsev, MC Begley, J Weger-Lucarelli, ... Cell host & microbe 23 (5), 672-685. e6, 2018 | 221 | 2018 |
| Trypsin treatment unlocks barrier for zoonotic bat coronavirus infection VD Menachery, KH Dinnon III, BL Yount Jr, ET McAnarney, LE Gralinski, ... Journal of virology 94 (5), 10.1128/jvi. 01774-19, 2020 | 210 | 2020 |
| MERS-CoV accessory ORFs play key role for infection and pathogenesis VD Menachery, HD Mitchell, AS Cockrell, LE Gralinski, BL Yount Jr, ... MBio 8 (4), 10.1128/mbio. 00665-17, 2017 | 142* | 2017 |
| Swine acute diarrhea syndrome coronavirus replication in primary human cells reveals potential susceptibility to infection CE Edwards, BL Yount, RL Graham, SR Leist, YJ Hou, KH Dinnon III, ... Proceedings of the National Academy of Sciences 117 (43), 26915-26925, 2020 | 122 | 2020 |
| Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as a live virus vaccine candidate W Sun, SR Leist, S McCroskery, Y Liu, S Slamanig, J Oliva, F Amanat, ... EBioMedicine 62, 2020 | 104 | 2020 |
| Middle East respiratory syndrome coronavirus nonstructural protein 16 is necessary for interferon resistance and viral pathogenesis VD Menachery, LE Gralinski, HD Mitchell, KH Dinnon III, SR Leist, ... MSphere 2 (6), 10.1128/msphere. 00346-17, 2017 | 94* | 2017 |
| A highly immunogenic and effective measles virus-based Th1-biased COVID-19 vaccine C Hörner, C Schürmann, A Auste, A Ebenig, S Muraleedharan, ... Proceedings of the National Academy of Sciences 117 (51), 32657-32666, 2020 | 88 | 2020 |
| SARS-CoV-2 RBD trimer protein adjuvanted with Alum-3M-052 protects from SARS-CoV-2 infection and immune pathology in the lung NK Routhu, N Cheedarla, VS Bollimpelli, S Gangadhara, VV Edara, L Lai, ... Nature communications 12 (1), 3587, 2021 | 84 | 2021 |
| A Newcastle disease virus (NDV) expressing a membrane-anchored spike as a cost-effective inactivated SARS-CoV-2 vaccine W Sun, S McCroskery, WC Liu, SR Leist, Y Liu, RA Albrecht, S Slamanig, ... Vaccines 8 (4), 771, 2020 | 83 | 2020 |
