| Three-dimensional human iPSC-derived artificial skeletal muscles model muscular dystrophies and enable multilineage tissue engineering SM Maffioletti, S Sarcar, ABH Henderson, I Mannhardt, L Pinton, LA Moyle, ... Cell Reports 23 (3), 899-908, 2018 | 278 | 2018 |
| Progressive motor neuron pathology and the role of astrocytes in a human stem cell model of VCP-related ALS CE Hall, Z Yao, M Choi, GE Tyzack, A Serio, R Luisier, J Harley, E Preza, ... Cell reports 19 (9), 1739-1749, 2017 | 193 | 2017 |
| Widespread FUS mislocalization is a molecular hallmark of amyotrophic lateral sclerosis GE Tyzack, R Luisier, DM Taha, J Neeves, M Modic, JS Mitchell, I Meyer, ... Brain 142 (9), 2572-2580, 2019 | 171 | 2019 |
| Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS R Luisier, GE Tyzack, CE Hall, JS Mitchell, H Devine, DM Taha, B Malik, ... Nature communications 9 (1), 1-15, 2018 | 152 | 2018 |
| Astrocyte response to motor neuron injury promotes structural synaptic plasticity via STAT3-regulated TSP-1 expression GE Tyzack, S Sitnikov, D Barson, KL Adams-Carr, NK Lau, JC Kwok, ... Nature communications 5 (1), 1-15, 2014 | 151 | 2014 |
| Kir4. 1-dependent astrocyte-fast motor neuron interactions are required for peak strength KW Kelley, LB Haim, L Schirmer, GE Tyzack, M Tolman, JG Miller, ... Neuron 98 (2), 306-319. e7, 2018 | 119 | 2018 |
| A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models GE Tyzack, CE Hall, CR Sibley, T Cymes, S Forostyak, G Carlino, ... Nature communications 8 (1), 1-17, 2017 | 114 | 2017 |
| Distinct responses of neurons and astrocytes to TDP-43 proteinopathy in amyotrophic lateral sclerosis P Smethurst, E Risse, GE Tyzack, JS Mitchell, DM Taha, YR Chen, ... Brain 143 (2), 430-440, 2020 | 91 | 2020 |
| New perspectives of tissue remodelling with neural stem and progenitor cell-based therapies C Cossetti, C Alfaro-Cervello, M Donegà, G Tyzack, S Pluchino Cell and tissue research 349 (1), 321-329, 2012 | 76 | 2012 |
| Regionally encoded functional heterogeneity of astrocytes in health and disease: A perspective BE Clarke, DM Taha, GE Tyzack, R Patani Glia 69 (1), 20-27, 2021 | 62 | 2021 |
| Human stem cell-derived astrocytes: specification and relevance for neurological disorders G Tyzack, A Lakatos, R Patani Current Stem Cell Reports 2 (3), 236-247, 2016 | 53 | 2016 |
| The FUS gene is dual‐coding with both proteins contributing to FUS‐mediated toxicity MA Brunet, JF Jacques, S Nassari, GE Tyzack, P McGoldrick, L Zinman, ... EMBO reports 22 (1), e50640, 2021 | 43 | 2021 |
| Astrocytes display cell autonomous and diverse early reactive states in familial amyotrophic lateral sclerosis. DM Taha, BE Clarke, CE Hall, GE Tyzack, OJ Ziff, L Greensmith, B Kalmar, ... Oxford University Press (OUP), 2022 | 33 | 2022 |
| Delineating astrocytic cytokine responses in a human stem cell model of neural trauma EP Thelin, CE Hall, GE Tyzack, A Frostell, S Giorgi-Coll, A Alam, ... Journal of neurotrauma 37 (1), 93-105, 2020 | 21 | 2020 |
| Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology OJ Ziff, J Neeves, J Mitchell, G Tyzack, C Martinez-Ruiz, R Luisier, ... Nature Communications 14 (1), 2176, 2023 | 20 | 2023 |
| Aberrant cytoplasmic intron retention is a blueprint for RNA binding protein mislocalization in VCP-related amyotrophic lateral sclerosis GE Tyzack, J Neeves, H Crerar, P Klein, O Ziff, DM Taha, R Luisier, ... Brain 144 (7), 1985-1993, 2021 | 20 | 2021 |
| Reactive astrocytes in ALS display diminished intron retention OJ Ziff, DM Taha, H Crerar, BE Clarke, AM Chakrabarti, G Kelly, J Neeves, ... Nucleic acids research 49 (6), 3168-3184, 2021 | 20 | 2021 |
| Axonal Length Determines distinct homeostatic phenotypes in human iPSC derived motor neurons on a bioengineered platform C Hagemann, C Moreno Gonzalez, L Guetta, G Tyzack, C Chiappini, ... Advanced Healthcare Materials 11 (10), 2101817, 2022 | 13 | 2022 |
| Automated and unbiased discrimination of ALS from control tissue at single cell resolution C Hagemann, GE Tyzack, DM Taha, H Devine, L Greensmith, ... Brain Pathology 31 (4), e12937, 2021 | 10 | 2021 |
| Physiological intron retaining transcripts in the cytoplasm abound during human motor neurogenesis MP Howe, H Crerar, J Neeves, J Harley, GE Tyzack, P Klein, A Ramos, ... Genome Research 32 (10), 1808-1825, 2022 | 8 | 2022 |
