Radioimmunotherapy of cancer with high linear energy transfer (LET) radiation delivered by radionuclides emitting α-particles or Auger electrons S Aghevlian, AJ Boyle, RM Reilly Advanced drug delivery reviews 109, 102-118, 2017 | 184 | 2017 |
Synthesis of polyglutamide-based metal-chelating polymers and their site-specific conjugation to trastuzumab for auger electron radioimmunotherapy Y Lu, G Ngo Ndjock Mbong, P Liu, C Chan, Z Cai, D Weinrich, AJ Boyle, ... Biomacromolecules 15 (6), 2027-2037, 2014 | 52 | 2014 |
MicroPET/CT imaging of patient-derived pancreatic cancer xenografts implanted subcutaneously or orthotopically in NOD-scid mice using 64Cu-NOTA-panitumumab F (ab') 2 fragments AJ Boyle, PJ Cao, DW Hedley, SS Sidhu, MA Winnik, RM Reilly Nuclear medicine and biology 42 (2), 71-77, 2015 | 45 | 2015 |
Effect of pendant group structure on the hydrolytic stability of polyaspartamide polymers under physiological conditions Y Lu, M Chau, AJ Boyle, P Liu, A Niehoff, D Weinrich, RM Reilly, ... Biomacromolecules 13 (5), 1296-1306, 2012 | 42 | 2012 |
Improving PET imaging acquisition and analysis with machine learning: a narrative review with focus on Alzheimer's disease and oncology IR Duffy, AJ Boyle, N Vasdev Molecular imaging 18, 1536012119869070, 2019 | 40 | 2019 |
Metal-chelating polymers (MCPs) with zwitterionic pendant groups complexed to trastuzumab exhibit decreased liver accumulation compared to polyanionic MCP immunoconjugates P Liu, AJ Boyle, Y Lu, J Adams, Y Chi, RM Reilly, MA Winnik Biomacromolecules 16 (11), 3613-3623, 2015 | 33 | 2015 |
Biotinylated polyacrylamide-based metal-chelating polymers and their influence on antigen recognition following conjugation to a trastuzumab Fab fragment P Liu, AJ Boyle, Y Lu, RM Reilly, MA Winnik Biomacromolecules 13 (9), 2831-2842, 2012 | 27 | 2012 |
The Effect of Metal-Chelating Polymers (MCPs) for 111In Complexed via the Streptavidin-Biotin System to Trastuzumab Fab Fragments on Tumor and Normal … AJ Boyle, P Liu, Y Lu, D Weinrich, DA Scollard, G Ngo Njock Mbong, ... Pharmaceutical research 30, 104-116, 2013 | 25 | 2013 |
Trastuzumab Labeled to High Specific Activity with 111In by Site-Specific Conjugation to a Metal-Chelating Polymer Exhibits Amplified Auger Electron-Mediated … G Ngo Ndjock Mbong, Y Lu, C Chan, Z Cai, P Liu, AJ Boyle, MA Winnik, ... Molecular Pharmaceutics 12 (6), 1951-1960, 2015 | 24 | 2015 |
Intracellular routing in breast cancer cells of streptavidin-conjugated trastuzumab Fab fragments linked to biotinylated doxorubicin-functionalized metal chelating polymers P Liu, Z Cai, JW Kang, AJ Boyle, J Adams, Y Lu, GNN Mbong, S Sidhu, ... Biomacromolecules 15 (3), 715-725, 2014 | 22 | 2014 |
Trastuzumab Labeled to High Specific Activity with (111) In by Site-Specific Conjugation to a Metal-Chelating Polymer Exhibits Amplified Auger Electron-Mediated Cytotoxicity on … Y Lu, C Chan, Z Cai, P Liu, AJ Boyle, MA Winnik, RM Reilly Molecular pharmaceutics 12 (6), 1951-1960, 2015 | 19 | 2015 |
Artificial intelligence for molecular neuroimaging AJ Boyle, VC Gaudet, SE Black, N Vasdev, P Rosa-Neto, KA Zukotynski Annals of Translational Medicine 9 (9), 2021 | 18 | 2021 |
EGFR-Targeted Metal Chelating Polymers (MCPs) Harboring Multiple Pendant PEG2K Chains for MicroPET/CT Imaging of Patient-Derived Pancreatic Cancer … Y Lu, AJ Boyle, PJ Cao, D Hedley, RM Reilly, MA Winnik ACS Biomaterials Science & Engineering 3 (3), 279-290, 2017 | 13 | 2017 |
Radiosynthesis of [11C]Ibrutinib via Pd-Mediated [11C]CO Carbonylation: Preliminary PET Imaging in Experimental Autoimmune Encephalomyelitis Mice A Lindberg, AJ Boyle, J Tong, MB Harkness, A Garcia, T Tran, D Zhai, ... Frontiers in Nuclear Medicine 1, 772289, 2021 | 12 | 2021 |
Repurposing 11C-PS13 for PET Imaging of Cyclooxygenase-1 in Ovarian Cancer Xenograft Mouse Models AJ Boyle, J Tong, SS Zoghbi, VW Pike, RB Innis, N Vasdev Journal of Nuclear Medicine 62 (5), 665-668, 2021 | 10 | 2021 |
PET Imaging of Fructose Metabolism in a Rodent Model of Neuroinflammation with 6-[18F]fluoro-6-deoxy-D-fructose AJ Boyle, E Murrell, J Tong, C Schifani, A Narvaez, M Wuest, F West, ... Molecules 27 (23), 8529, 2022 | 8 | 2022 |
Radioimmunotherapy of human pancreatic cancer xenografts in NOD-scid mice with [64Cu] Cu-NOTA-panitumumab F (ab′) 2 alone or combined with radiosensitizing gemcitabine and the … AJ Boyle, PJ Cao, Z Cai, C Chan, DW Hedley, RM Reilly Nuclear Medicine and Biology 84, 46-54, 2020 | 6 | 2020 |
PET imaging of glycogen synthase kinase-3 in pancreatic cancer xenograft mouse models AJ Boyle, A Narvaez, M Chassé, N Vasdev American Journal of Nuclear Medicine and Molecular Imaging 12 (1), 1, 2022 | 5 | 2022 |
Synthesis of a metal-chelating polymer with NOTA pendants as a carrier for 64Cu, intended for radioimmunotherapy H Cho, P Liu, AJ Boyle, RM Reilly, MA Winnik European Polymer Journal 125, 109501, 2020 | 3 | 2020 |
Relative Biological Effectiveness (RBE) of [64Cu] Cu and [177Lu] Lu-NOTA-panitumumab F (ab') 2 radioimmunotherapeutic agents vs. γ-radiation for decreasing the clonogenic … AJ Boyle, Z Cai, S O’Brien, J Crick, S Angers, RM Reilly Nuclear Medicine and Biology 122, 108367, 2023 | 2 | 2023 |