| CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes G Luo, M Cunningham, S Kim, T Burn, J Lin, M Sinz, G Hamilton, C Rizzo, ... Drug Metabolism and Disposition 30 (7), 795-804, 2002 | 559 | 2002 |
| Preclinical experimental models of drug metabolism and disposition in drug discovery and development D Zhang, G Luo, X Ding, C Lu Acta Pharmaceutica Sinica B 2 (6), 549-561, 2012 | 374 | 2012 |
| CYP3A4 induction by xenobiotics: biochemistry, experimental methods and impact on drug discovery and development G Luo, T Guenthner, LS Gan, WG Humphreys Current drug metabolism 5 (6), 483-505, 2004 | 198 | 2004 |
| Cloning and expression of murine CYP2Cs and their ability to metabolize arachidonic acid G Luo, DC Zeldin, JA Blaisdell, E Hodgson, JA Goldstein Archives of biochemistry and biophysics 357 (1), 45-57, 1998 | 143 | 1998 |
| Investigation of the role of the 2′, 3′-epoxidation pathway in the bioactivation and genotoxicity of dietary allylbenzene analogs TM Guenthner, G Luo Toxicology 160 (1-3), 47-58, 2001 | 94 | 2001 |
| Mouse Liver CYP2C39 Is a Novel Retinoic Acid 4-Hydroxylase. F Andreola, GP Hayhurst, G Luo, SS Ferguson, FJ Gonzalez, JA Goldstein, ... Journal of Biological Chemistry 279 (5), 3434-3438, 2004 | 85 | 2004 |
| Molecular characterization of the murine HIF-1α locus G Luo, YZ Gu, S Jain, WK Chan, KM Carr, JB Hogenesch, CA Bradfield Gene expression 6 (5), 287, 1997 | 81 | 1997 |
| Identification and localization of five CYP2Cs in murine extrahepatic tissues and their metabolism of arachidonic acid to regio-and stereoselective products CC Tsao, SJ Coulter, A Chien, G Luo, NP Clayton, R Maronpot, ... Journal of Pharmacology and Experimental Therapeutics 299 (1), 39-47, 2001 | 65 | 2001 |
| Hydrolysis of the 2', 3'-allylic epoxides of allylbenzene, estragole, eugenol, and safrole by both microsomal and cytosolic epoxide hydrolases. G Luo, MK Qato, TM Guenthner Drug metabolism and disposition 20 (3), 440-445, 1992 | 61 | 1992 |
| Covalent binding to DNA in vitro of 2', 3'-oxides derived from allylbenzene analogs. G Luo, TM Guenthner Drug metabolism and disposition 24 (9), 1020-1027, 1996 | 58 | 1996 |
| Preclinical evaluation of the metabolism and disposition of RRx-001, a novel investigative anticancer agent J Scicinski, B Oronsky, M Taylor, G Luo, T Musick, J Marini, CM Adams, ... Drug Metabolism and Disposition 40 (9), 1810-1816, 2012 | 57 | 2012 |
| Concurrent induction and mechanism-based inactivation of CYP3A4 by an L-valinamide derivative G Luo, J Lin, WD Fiske, R Dai, TJ Yang, S Kim, M Sinz, E LeCluyse, ... Drug metabolism and disposition 31 (9), 1170-1175, 2003 | 54 | 2003 |
| Metabolism of allylbenzene 2', 3'-oxide and estragole 2', 3'-oxide in the isolated perfused rat liver. G Luo, TM Guenthner Journal of Pharmacology and Experimental Therapeutics 272 (2), 588-596, 1995 | 40 | 1995 |
| In silico prediction of biliary excretion of drugs in rats based on physicochemical properties G Luo, S Johnson, MM Hsueh, J Zheng, H Cai, B Xin, S Chong, K He, ... Drug metabolism and disposition 38 (3), 422-430, 2010 | 37 | 2010 |
| Development of an in situ toxicity assay system using recombinant baculoviruses DF Grant, JF Greene, F Pinot, B Borhan, MF Moghaddam, BD Hammock, ... Biochemical pharmacology 51 (4), 503-515, 1996 | 35 | 1996 |
| Design and synthesis of phenylpyrrolidine phenylglycinamides as highly potent and selective TF-FVIIa inhibitors X Zhang, W Jiang, S Jacutin-Porte, PW Glunz, Y Zou, X Cheng, ... ACS Medicinal Chemistry Letters 5 (2), 188-192, 2014 | 23 | 2014 |
| The role of P-glycoprotein in drug disposition: significance to drug development MD Troutman, G Luo, LS Gan, DR Thakker Drug–Drug Interactions, 295-357, 2002 | 20* | 2002 |
| Detoxication of the 2', 3'-epoxide metabolites of allylbenzene and estragole. Conjugation with glutathione. G Luo, TM Guenthner Drug metabolism and disposition 22 (5), 731-737, 1994 | 19 | 1994 |
| Analysis of CYP mRNA expression by branched DNA technology M Czerwinski, P Opdam, A Madan, K Carroll, DR Mudra, LL Gan, G Luo, ... Academic Press 357, 170-179, 2002 | 17 | 2002 |
| Interaction of ritonavir on tissue distribution of a [14C] L-valinamide, a potent human immunodeficiency virus-1 protease inhibitor, in rats using quantitative whole-body … EG Solon, SK Balani, G Luo, TJ Yang, PJ Haines, L Wang, T Demond, ... Drug metabolism and disposition 30 (11), 1164-1169, 2002 | 14 | 2002 |
