| Colchicine-binding site inhibitors from chemistry to clinic: a review EC McLoughlin, NM O’Boyle Pharmaceuticals 13 (1), 8, 2020 | 250 | 2020 |
| Synthesis and evaluation of azetidinone analogues of combretastatin A-4 as tubulin targeting agents NM O’Boyle, M Carr, LM Greene, O Bergin, SM Nathwani, T McCabe, ... Journal of medicinal chemistry 53 (24), 8569-8584, 2010 | 158 | 2010 |
| Skin lipids in health and disease: A review S Knox, NM O’Boyle Chemistry and physics of lipids 236, 105055, 2021 | 114 | 2021 |
| Synthesis, evaluation and structural studies of antiproliferative tubulin-targeting azetidin-2-ones NM O’Boyle, LM Greene, O Bergin, JB Fichet, T McCabe, DG Lloyd, ... Bioorganic & medicinal chemistry 19 (7), 2306-2325, 2011 | 85 | 2011 |
| Synthesis and biochemical evaluation of 3-phenoxy-1, 4-diarylazetidin-2-ones as tubulin-targeting antitumor agents TF Greene, S Wang, LM Greene, SM Nathwani, JK Pollock, AM Malebari, ... Journal of medicinal chemistry 59 (1), 90-113, 2016 | 66 | 2016 |
| Special issue “anticancer drugs” MJ Meegan, NM O’Boyle Pharmaceuticals 12 (3), 134, 2019 | 56 | 2019 |
| β-Lactam estrogen receptor antagonists and a dual-targeting estrogen receptor/tubulin ligand NM O’Boyle, JK Pollock, M Carr, AJS Knox, SM Nathwani, S Wang, ... Journal of Medicinal Chemistry 57 (22), 9370-9382, 2014 | 53 | 2014 |
| The vascular targeting agent Combretastatin-A4 directly induces autophagy in adenocarcinoma-derived colon cancer cells LM Greene, NM O’Boyle, DP Nolan, MJ Meegan, DM Zisterer Biochemical pharmacology 84 (5), 612-624, 2012 | 53 | 2012 |
| Piperlongumine (piplartine) and analogues: Antiproliferative microtubule-destabilising agents MJ Meegan, S Nathwani, B Twamley, DM Zisterer, NM O'Boyle European Journal of Medicinal Chemistry 125, 453-463, 2017 | 51 | 2017 |
| Synthesis, biochemical and molecular modelling studies of antiproliferative azetidinones causing microtubule disruption and mitotic catastrophe NM O’Boyle, M Carr, LM Greene, NO Keely, AJS Knox, T McCabe, ... European journal of medicinal chemistry 46 (9), 4595-4607, 2011 | 51 | 2011 |
| β-Lactam analogues of combretastatin A-4 prevent metabolic inactivation by glucuronidation in chemoresistant HT-29 colon cancer cells AM Malebari, LM Greene, SM Nathwani, D Fayne, NM O'Boyle, S Wang, ... European journal of medicinal chemistry 130, 261-285, 2017 | 44 | 2017 |
| Lead optimization of benzoxepin-type selective estrogen receptor (ER) modulators and downregulators with subtype-specific ERα and ERβ activity NM O’Boyle, I Barrett, LM Greene, M Carr, D Fayne, B Twamley, AJS Knox, ... Journal of medicinal chemistry 61 (2), 514-534, 2018 | 38 | 2018 |
| The vascular targeting agent combretastatin-A4 and a novel cis-restricted β-lactam analogue, CA-432, induce apoptosis in human chronic myeloid leukemia cells and ex vivo … LM Greene, SM Nathwani, SA Bright, D Fayne, A Croke, M Gagliardi, ... Journal of Pharmacology and Experimental Therapeutics 335 (2), 302-313, 2010 | 38 | 2010 |
| β-Lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cells AM Malebari, D Fayne, SM Nathwani, F O’Connell, S Noorani, B Twamley, ... European Journal of Medicinal Chemistry 189, 112050, 2020 | 36 | 2020 |
| Analogues of the epoxy resin monomer diglycidyl ether of bisphenol F: effects on contact allergenic potency and cytotoxicity NM O'Boyle, T Delaine, K Luthman, A Natsch, AT Karlberg Chemical Research in Toxicology 25 (11), 2469-2478, 2012 | 36 | 2012 |
| Lead identification of β-lactam and related imine inhibitors of the molecular chaperone heat shock protein 90 NM O’Boyle, AJS Knox, TT Price, DC Williams, DM Zisterer, DG Lloyd, ... Bioorganic & medicinal chemistry 19 (20), 6055-6068, 2011 | 29 | 2011 |
| Combretazet-3 a novel synthetic cis-stable combretastatin A-4-azetidinone hybrid with enhanced stability and therapeutic efficacy in colon cancer LM Greene, S Wang, NM O'Boyle, SA Bright, JE Reid, P Kelly, MJ Meegan, ... Oncology reports 29 (6), 2451-2458, 2013 | 27 | 2013 |
| Synthesis and biochemical activities of antiproliferative amino acid and phosphate derivatives of microtubule-disrupting β-lactam combretastatins NM O'Boyle, LM Greene, NO Keely, S Wang, TS Cotter, DM Zisterer, ... European journal of medicinal chemistry 62, 705-721, 2013 | 27 | 2013 |
| Novel cis-restricted β-lactam combretastatin A-4 analogues display anti-vascular and anti-metastatic properties in vitro SM Nathwani, L Hughes, LM Greene, M Carr, NM O'Boyle, S McDonnell, ... Oncology reports 29 (2), 585-594, 2013 | 26 | 2013 |
| Combretastatin (CA)-4 and its novel analogue CA-432 impair T-cell migration through the Rho/ROCK signalling pathway JK Pollock, NK Verma, NM O’Boyle, M Carr, MJ Meegan, DM Zisterer Biochemical Pharmacology 92 (4), 544-557, 2014 | 21 | 2014 |
