STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma F Skoulidis, ME Goldberg, DM Greenawalt, MD Hellmann, MM Awad, ... Cancer discovery 8 (7), 822-835, 2018 | 1292 | 2018 |
Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment Y Kfoury, N Baryawno, N Severe, S Mei, K Gustafsson, T Hirz, T Brouse, ... Cancer cell 39 (11), 1464-1478. e8, 2021 | 122 | 2021 |
Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses T Hirz, S Mei, H Sarkar, Y Kfoury, S Wu, BM Verhoeven, AO Subtelny, ... Nature Communications 14 (1), 663, 2023 | 55 | 2023 |
Reversal of lactate and PD-1–mediated macrophage immunosuppression controls growth of PTEN/p53-deficient prostate cancer K Chaudagar, HM Hieromnimon, R Khurana, B Labadie, T Hirz, S Mei, ... Clinical Cancer Research 29 (10), 1952-1968, 2023 | 31 | 2023 |
A subset of localized prostate cancer displays an immunogenic phenotype associated with losses of key tumor suppressor genes C Calagua, M Ficial, CS Jansen, T Hirz, L Del Balzo, S Wilkinson, R Lake, ... Clinical Cancer Research 27 (17), 4836-4847, 2021 | 26 | 2021 |
Thiazole derivatives as inhibitors of cyclooxygenases in vitro and in vivo GA El-Achkar, M Jouni, MF Mrad, T Hirz, N El Hachem, A Khalaf, ... European journal of pharmacology 750, 66-73, 2015 | 25 | 2015 |
STK11/LKB1 mutations and PD-1 inhibitor resistance in KRAS-mutant lung adenocarcinoma. Cancer Discov. 2018; 8 (7): 822–835. doi: 10.1158/2159-8290 F Skoulidis, ME Goldberg, DM Greenawalt, MD Hellmann, MM Awad, ... CD-18-0099, 0 | 25 | |
STK11/LKB1 mutations and PD-1 inhibitor resistance in KRAS-mutant lung adenocarcinoma. Cancer Discov. 2018; 8 (7): 822–35 F Skoulidis, ME Goldberg, DM Greenawalt, MD Hellmann, MM Awad, ... External Resources Crossref (DOI), 0 | 24 | |
A transcriptional metastatic signature predicts survival in clear cell renal cell carcinoma AM Alchahin, S Mei, I Tsea, T Hirz, Y Kfoury, D Dahl, CL Wu, AO Subtelny, ... Nature communications 13 (1), 5747, 2022 | 23 | 2022 |
Targeting of CD40 and PD-L1 pathways inhibits progression of oral premalignant lesions in a carcinogen-induced model of oral squamous cell carcinoma JA Monteiro de Oliveira Novaes, T Hirz, I Guijarro, M Nilsson, MA Pisegna, ... Cancer Prevention Research 14 (3), 313-324, 2021 | 23 | 2021 |
STK11/LKB1 mutations and PD-1 inhibitor resistance in KRAS-mutant lung adenocarcinoma. Cancer Discov 8: 822–835 F Skoulidis, ME Goldberg, DM Greenawalt, MD Hellmann, MM Awad, ... | 16 | 2018 |
Neutrophils protect lymphoma cells against cytotoxic and targeted therapies through CD11b/ICAM-1 binding T Hirz, EL Matera, K Chettab, LP Jordheim, D Mathé, A Evesque, ... Oncotarget 8 (42), 72818, 2017 | 15 | 2017 |
Neutrophil isolation and analysis to determine their role in lymphoma cell sensitivity to therapeutic agents T Hirz, C Dumontet JoVE (Journal of Visualized Experiments), e53846, 2016 | 14 | 2016 |
STK11/LKB1 mutations and PD-1 inhibitor resistance in KRAS-mutant lung adenocarcinoma. Cancer Discov 8 (7): 822–835 F Skoulidis, ME Goldberg, DM Greenawalt, MD Hellmann, MM Awad, ... | 13 | 2018 |
Biological and anti-inflammatory evaluation of two thiazole compounds in RAW cell line: potential cyclooxygenase-2 specific inhibitors E Hamade, A Habib, A Hachem, A H Hussein, M Abbas, T Hirz, M Al Masri, ... Medicinal Chemistry 8 (3), 401-408, 2012 | 12 | 2012 |
Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment N Baryawno, Y Kfoury, N Severe, S Mei, K Gustafsson, T Hirz, T Brouse, ... | 5 | 2020 |
New analogues of 13-hydroxyocatdecadienoic acid and 12-hydroxyeicosatetraenoic acid block human blood platelet aggregation and cyclooxygenase-1 activity T Hirz, A Khalaf, N El-Hachem, MF Mrad, H Abdallah, C Créminon, ... Chemistry Central Journal 6, 1-11, 2012 | 5 | 2012 |
Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress BT Do, PP Hsu, SY Vermeulen, Z Wang, T Hirz, KL Abbott, N Aziz, ... Developmental Cell, 2024 | 4 | 2024 |
Single-cell analysis of immune and stroma cell remodeling in clear cell renal cell carcinoma primary tumors and bone metastatic lesions S Mei, AM Alchahin, I Tsea, Y Kfoury, T Hirz, NE Jeffries, T Zhao, Y Xu, ... Genome Medicine 16 (1), 1, 2024 | 4 | 2024 |
Impact of metastatic prostate cancer on human bone marrow N Baryawno, Y Kfoury, N Severe, S Mei, T Hirz, K Gustafsson, T Brouse, ... BioRxiv, 2020.03. 19.998658, 2020 | 4 | 2020 |