Molecular basis for the differential use of glucose and glutamine in cell proliferation as revealed by synchronized HeLa cells SL Colombo, M Palacios-Callender, N Frakich, S Carcamo, I Kovacs, ... Proceedings of the National Academy of Sciences 108 (52), 21069-21074, 2011 | 187 | 2011 |
Two ubiquitin ligases, APC/C-Cdh1 and SKP1-CUL1-F (SCF)-β-TrCP, sequentially regulate glycolysis during the cell cycle S Tudzarova, SL Colombo, K Stoeber, S Carcamo, GH Williams, ... Proceedings of the National Academy of Sciences 108 (13), 5278-5283, 2011 | 135 | 2011 |
Cdc7 kinase is a predictor of survival and a novel therapeutic target in epithelial ovarian carcinoma AA Kulkarni, SR Kingsbury, S Tudzarova, HK Hong, M Loddo, M Rashid, ... Clinical Cancer Research 15 (7), 2417-2425, 2009 | 111 | 2009 |
IAPP toxicity activates HIF1α/PFKFB3 signaling delaying β-cell loss at the expense of β-cell function C Montemurro, H Nomoto, L Pei, VS Parekh, KE Vongbunyong, ... Nature communications 10 (1), 2679, 2019 | 81 | 2019 |
Activation of the HIF1α/PFKFB3 stress response pathway in beta cells in type 1 diabetes H Nomoto, L Pei, C Montemurro, M Rosenberger, A Furterer, G Coppola, ... Diabetologia 63, 149-161, 2020 | 61 | 2020 |
Pregnancy‐associated plasma protein A regulates mitosis and is epigenetically silenced in breast cancer M Loddo, J Andryszkiewicz, S Rodriguez‐Acebes, K Stoeber, A Jones, ... The Journal of Pathology 233 (4), 344-356, 2014 | 57 | 2014 |
Molecular architecture of the DNA replication origin activation checkpoint S Tudzarova, MWB Trotter, A Wollenschlaeger, C Mulvey, ... The EMBO journal 29 (19), 3381-3394, 2010 | 56 | 2010 |
The role of HIF1α-PFKFB3 pathway in diabetic retinopathy J Min, T Zeng, M Roux, D Lazar, L Chen, S Tudzarova The Journal of Clinical Endocrinology & Metabolism 106 (9), 2505-2519, 2021 | 47 | 2021 |
Cell cycle–related metabolism and mitochondrial dynamics in a replication-competent pancreatic beta-cell line C Montemurro, S Vadrevu, T Gurlo, AE Butler, KE Vongbunyong, ... Cell Cycle 16 (21), 2086-2099, 2017 | 42 | 2017 |
In vivo activated caspase‐3 cleaves PARP‐1 in rat liver after administration of the hepatocarcinogen N‐nitrosomorpholine (NNM) generating the 85 kDa fragment J Węsierska‐Gądek, M Gueorguieva, J Wojciechowski, ... Journal of cellular biochemistry 93 (4), 774-787, 2004 | 33 | 2004 |
Cdc7 is a potent anti-cancer target in pancreatic cancer due to abrogation of the DNA origin activation checkpoint MT Huggett, S Tudzarova, I Proctor, M Loddo, MG Keane, K Stoeber, ... Oncotarget 7 (14), 18495, 2016 | 27 | 2016 |
p53 controls CDC7 levels to reinforce G1 cell cycle arrest upon genotoxic stress S Tudzarova, P Mulholland, A Dey, K Stoeber, AL Okorokov, GH Williams Cell Cycle 15 (21), 2958-2972, 2016 | 26 | 2016 |
The double trouble of metabolic diseases: the diabetes–cancer link S Tudzarova, MA Osman Molecular biology of the cell 26 (18), 3129-3139, 2015 | 26 | 2015 |
Subcellular proteomics reveals a role for nucleo-cytoplasmic trafficking at the DNA replication origin activation checkpoint CM Mulvey, S Tudzarova, M Crawford, GH Williams, K Stoeber, ... Journal of proteome research 12 (3), 1436-1453, 2013 | 23 | 2013 |
Exploring the Interaction Between siRNA and the SMoC Biomolecule Transporters: Implications for Small Molecule–Mediated Delivery of siRNA M Gooding, S Tudzarova, RJ Worthington, SR Kingsbury, AS Rebstock, ... Chemical biology & drug design 79 (1), 9-21, 2012 | 14 | 2012 |
Quantitative proteomics reveals a “poised quiescence” cellular state after triggering the DNA replication origin activation checkpoint C Mulvey, S Tudzarova, M Crawford, GH Williams, K Stoeber, ... Journal of proteome research 9 (10), 5445-5460, 2010 | 9 | 2010 |
Strong induction of p73 protein in vivo coincides with the onset of apoptosis in rat liver after treatment with the hepatocarcinogen N‐nitrosomorpholine (NNM) S Tudzarova‐Trajkovska, J Wȩsierska‐Ga̧dek Journal of cellular biochemistry 90 (4), 837-855, 2003 | 8 | 2003 |
Targeting DNA replication before it starts: Cdc7 as a therapeutic target in p53 mutant Her2 and triple negative breast cancer R Sainsbury, I Proctor, S Rodriguez, M Loddo, S Tudzarova, K Stoeber, ... Breast Cancer Research 12, 1-2, 2010 | 5 | 2010 |
β-cell-specific deletion of PFKFB3 restores cell fitness competition and physiological replication under diabetogenic stress J Min, F Ma, B Seyran, M Pellegrini, O Greeff, S Moncada, S Tudzarova Communications Biology 5 (1), 248, 2022 | 1 | 2022 |
Transient glycolysis enables mitochondrial fusion and stimulates S phase entry: the role of FoxO3a S Tudzarova-Trajkovska, S Moncada JOP. Journal of the Pancreas 15 (5), 531-531, 2014 | 1 | 2014 |