Sildenafil reverses ABCB1-and ABCG2-mediated chemotherapeutic drug resistance Z Shi, AK Tiwari, S Shukla, RW Robey, S Singh, IW Kim, SE Bates, ... Cancer research 71 (8), 3029-3041, 2011 | 183 | 2011 |
Nilotinib potentiates anticancer drug sensitivity in murine ABCB1-, ABCG2-, and ABCC10-multidrug resistance xenograft models AK Tiwari, K Sodani, C Dai, AH Abuznait, S Singh, ZJ Xiao, A Patel, ... Cancer letters 328 (2), 307-317, 2013 | 127 | 2013 |
Multiple transport-active binding sites are available for a single substrate on human P-glycoprotein (ABCB1) EE Chufan, K Kapoor, HM Sim, S Singh, TT Talele, SR Durell, ... PloS one 8 (12), e82463, 2013 | 121 | 2013 |
Neratinib reverses ATP-binding cassette B1-mediated chemotherapeutic drug resistance in vitro, in vivo, and ex vivo X Zhao, J Xie, X Chen, HM Sim, X Zhang, Y Liang, S Singh, TT Talele, ... Molecular pharmacology 82 (1), 47-58, 2012 | 95 | 2012 |
The phosphodiesterase-5 inhibitor vardenafil is a potent inhibitor of ABCB1/P-glycoprotein transporter PR Ding, AK Tiwari, S Ohnuma, JWKK Lee, X An, CL Dai, QS Lu, S Singh, ... PloS one 6 (4), e19329, 2011 | 93 | 2011 |
Structure-based virtual screening, synthesis and SAR of novel inhibitors of hepatitis C virus NS5B polymerase TT Talele, P Arora, SS Kulkarni, MR Patel, S Singh, M Chudayeu, ... Bioorganic & medicinal chemistry 18 (13), 4630-4638, 2010 | 92 | 2010 |
Design and synthesis of human ABCB1 (P-glycoprotein) inhibitors by peptide coupling of diverse chemical scaffolds on carboxyl and amino termini of (S)-valine-derived thiazole … S Singh, NR Prasad, EE Chufan, BA Patel, YJ Wang, ZS Chen, ... Journal of medicinal chemistry 57 (10), 4058-4072, 2014 | 63 | 2014 |
GW583340 and GW2974, human EGFR and HER-2 inhibitors, reverse ABCG2-and ABCB1-mediated drug resistance K Sodani, AK Tiwari, S Singh, A Patel, ZJ Xiao, JJ Chen, YL Sun, ... Biochemical pharmacology 83 (12), 1613-1622, 2012 | 62 | 2012 |
Telatinib reverses chemotherapeutic multidrug resistance mediated by ABCG2 efflux transporter in vitro and in vivo K Sodani, A Patel, N Anreddy, S Singh, DH Yang, RJ Kathawala, P Kumar, ... Biochemical pharmacology 89 (1), 52-61, 2014 | 58 | 2014 |
PD173074, a selective FGFR inhibitor, reverses ABCB1-mediated drug resistance in cancer cells. ZSC Atish Patel, Amit K. Tiwari, Eduardo E. Chufan Cancer Chemotherapy and Pharmacology, 2013 | 58 | 2013 |
The synthesis of phenylalanine-derived C5-substituted rhodanines and their activity against selected methicillin-resistant Staphylococcus aureus (MRSA) strains D Hardej, CR Ashby Jr, NS Khadtare, SS Kulkarni, S Singh, TT Talele European journal of medicinal chemistry 45 (12), 5827-5832, 2010 | 58 | 2010 |
Blockade of Her2/neu Binding to Hsp90 by Emodin Azide Methyl Anthraquinone Derivative Induces Proteasomal Degradation of Her2/neu Y Yan, L Zheng, X Zhang, L Chen, S Singh, F Wang, J Zhang, Y Liang, ... Molecular pharmaceutics 8 (5), 1687-1697, 2011 | 56 | 2011 |
Saracatinib (AZD0530) is a potent modulator of ABCB1‐mediated multidrug resistance in vitro and in vivo KJ Liu, JH He, XD Su, HM Sim, JD Xie, XG Chen, F Wang, YJ Liang, ... International journal of cancer 132 (1), 224-235, 2013 | 55 | 2013 |
Synthesis and SAR optimization of quinazolin-4 (3H)-ones as poly (ADP-ribose) polymerase-1 inhibitors SS Kulkarni, S Singh, JR Shah, WK Low, TT Talele European journal of medicinal chemistry 50, 264-273, 2012 | 51 | 2012 |
Centrosomal kinase Nek2 cooperates with oncogenic pathways to promote metastasis TK Das, D Dana, SS Paroly, SK Perumal, S Singh, H Jhun, J Pendse, ... Oncogenesis 2 (9), e69-e69, 2013 | 49 | 2013 |
Endophytes enhance the production of root alkaloids ajmalicine and serpentine by modulating the terpenoid indole alkaloid pathway in Catharanthus roseus roots S Singh, SS Pandey, K Shanker, A Kalra Journal of applied microbiology 128 (4), 1128-1142, 2020 | 43 | 2020 |
Enhancing chemosensitivity in ABCB1-and ABCG2-overexpressing cells and cancer stem-like cells by an Aurora kinase inhibitor CCT129202 C Cheng, Z Liu, H Zhang, J Xie, X Chen, X Zhao, F Wang, Y Liang, ... Molecular Pharmaceutics 9 (7), 1971-1982, 2012 | 42 | 2012 |
Nitrofuranyl methyl piperazines as new anti-TB agents: identification, validation, medicinal chemistry, and PK studies KR Yempalla, G Munagala, S Singh, A Magotra, S Kumar, VS Rajput, ... ACS Medicinal Chemistry Letters 6 (10), 1041-1046, 2015 | 39 | 2015 |
QSAR studies on benzoylaminobenzoic acid derivatives as inhibitors of β-ketoacyl-acyl carrier protein synthase III S Singh, LK Soni, MK Gupta, YS Prabhakar, SG Kaskhedikar European journal of medicinal chemistry 43 (5), 1071-1080, 2008 | 35 | 2008 |
Sensors for diabetes: glucose biosensors by using different newer techniques: a review GM Niraj, H Varshney, S Pandey, S Singh Int. J. Ther. Appl 6, 28-37, 2012 | 34 | 2012 |