Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance SM Shaffer, MC Dunagin, SR Torborg, EA Torre, B Emert, C Krepler, ... Nature 546 (7658), 431-435, 2017 | 1104 | 2017 |
SAVER: gene expression recovery for single-cell RNA sequencing M Huang, J Wang, E Torre, H Dueck, S Shaffer, R Bonasio, JI Murray, ... Nature methods 15 (7), 539-542, 2018 | 669 | 2018 |
Memory sequencing reveals heritable single-cell gene expression programs associated with distinct cellular behaviors SM Shaffer, BL Emert, RAR Hueros, C Cote, G Harmange, DL Schaff, ... Cell 182 (4), 947-959. e17, 2020 | 168 | 2020 |
Gene expression distribution deconvolution in single-cell RNA sequencing J Wang, M Huang, E Torre, H Dueck, S Shaffer, J Murray, A Raj, M Li, ... Proceedings of the National Academy of Sciences 115 (28), E6437-E6446, 2018 | 131 | 2018 |
Variability within rare cell states enables multiple paths toward drug resistance BL Emert, CJ Cote, EA Torre, IP Dardani, CL Jiang, N Jain, SM Shaffer, ... Nature biotechnology 39 (7), 865-876, 2021 | 125 | 2021 |
Turbo FISH: a method for rapid single molecule RNA FISH SM Shaffer, MT Wu, MJ Levesque, A Raj PloS one 8 (9), e75120, 2013 | 120 | 2013 |
Rare cell detection by single-cell RNA sequencing as guided by single-molecule RNA FISH E Torre, H Dueck, S Shaffer, J Gospocic, R Gupte, R Bonasio, J Kim, ... Cell systems 6 (2), 171-179. e5, 2018 | 119 | 2018 |
A slow-cycling subpopulation of melanoma cells with highly invasive properties M Perego, M Maurer, JX Wang, S Shaffer, AC Müller, K Parapatics, L Li, ... Oncogene 37 (3), 302-312, 2018 | 78 | 2018 |
Transcriptional bursting explains the noise–versus–mean relationship in mRNA and protein levels RD Dar, SM Shaffer, A Singh, BS Razooky, ML Simpson, A Raj, ... PloS one 11 (7), e0158298, 2016 | 75 | 2016 |
TooManyCells identifies and visualizes relationships of single-cell clades GW Schwartz, Y Zhou, J Petrovic, M Fasolino, L Xu, SM Shaffer, WS Pear, ... Nature methods 17 (4), 405-413, 2020 | 69 | 2020 |
Islet transplantation in type I diabetes mellitus NA Jamiolkowski RM, Guo LY, Li YR, Shaffer SM Yale Journal of Biology and Medicine 85, 37-43, 2012 | 58 | 2012 |
Genetic screening for single-cell variability modulators driving therapy resistance EA Torre, E Arai, S Bayatpour, CL Jiang, LE Beck, BL Emert, SM Shaffer, ... Nature genetics 53 (1), 76-85, 2021 | 56 | 2021 |
Multiplexed detection of viral infections using rapid in situ RNA analysis on a chip SM Shaffer, RP Joshi, BS Chambers, D Sterken, AG Biaesch, DJ Gabrieli, ... Lab on a Chip 15 (15), 3170-3182, 2015 | 26 | 2015 |
Disrupting cellular memory to overcome drug resistance G Harmange, RAR Hueros, DL Schaff, B Emert, M Saint-Antoine, LC Kim, ... Nature communications 14 (1), 7130, 2023 | 20 | 2023 |
Subcellular detection of SARS-CoV-2 RNA in human tissue reveals distinct localization in alveolar type 2 pneumocytes and alveolar macrophages KK Acheampong, DL Schaff, BL Emert, J Lake, S Reffsin, EK Shea, ... MBio 13 (1), e03751-21, 2022 | 17 | 2022 |
Correction: Corrigendum: Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance SM Shaffer, MC Dunagin, SR Torborg, EA Torre, B Emert, C Krepler, ... Nature 555 (7695), 274-274, 2018 | 8 | 2018 |
E-cigarette use and respiratory symptoms in residents of the United States: A BRFSS report MH Varella, OA Andrade, SM Shaffer, G Castro, P Rodriguez, ... Plos one 17 (12), e0269760, 2022 | 7 | 2022 |
Integrating mutational and nonmutational mechanisms of acquired therapy resistance within the Darwinian paradigm R Vander Velde, S Shaffer, A Marusyk Trends in cancer 8 (6), 456-466, 2022 | 7 | 2022 |
Validation of a next-generation sequencing oncology panel optimized for low input DNA RT Sussman, S Shaffer, EM Azzato, D DeSloover, MS Farooqi, A Meyer, ... Cancer Genetics 228, 55-63, 2018 | 7 | 2018 |
A comparison between single cell RNA sequencing and single molecule RNA FISH for rare cell analysis E Torre, H Dueck, S Shaffer, J Gospocic, R Gupte, R Bonasio, J Kim, ... bioRxiv, 138289, 2017 | 7 | 2017 |