Proteostasis and beyond: ATF6 in ischemic disease CC Glembotski, JD Rosarda, RL Wiseman Trends in molecular medicine 25 (6), 538-550, 2019 | 84 | 2019 |
Metabolically activated proteostasis regulators protect against glutamate toxicity by activating NRF2 JD Rosarda, KR Baron, K Nutsch, GM Kline, C Stanton, JW Kelly, ... ACS Chemical Biology 16 (12), 2852-2863, 2021 | 24 | 2021 |
A library of ATTR amyloidosis patient-specific induced pluripotent stem cells for disease modelling and in vitro testing of novel therapeutics RM Giadone, JD Rosarda, PR Akepati, AC Thomas, B Boldbaatar, ... Amyloid 25 (3), 148-155, 2018 | 16 | 2018 |
Expression of amyloidogenic transthyretin drives hepatic proteostasis remodeling in an induced pluripotent stem cell model of systemic amyloid disease RM Giadone, DC Liberti, TM Matte, JD Rosarda, C Torres-Arancivia, ... Stem Cell Reports 15 (2), 515-528, 2020 | 12 | 2020 |
Imbalanced unfolded protein response signaling contributes to 1-deoxysphingolipid retinal toxicity JD Rosarda, S Giles, S Harkins-Perry, EA Mills, M Friedlander, ... Nature Communications 14 (1), 4119, 2023 | 10 | 2023 |
Pharmacologic activation of a compensatory integrated stress response kinase promotes mitochondrial remodeling in PERK-deficient cells V Perea, KR Baron, V Dolina, G Aviles, G Kim, JD Rosarda, X Guo, ... Cell Chemical Biology 30 (12), 1571-1584. e5, 2023 | 8 | 2023 |
Covalent targeting as a common mechanism for inhibiting NLRP3 inflammasome assembly C Stanton, J Sun, K Nutsch, JD Rosarda, T Nguyen, C Li-Ma, E Njomen, ... ACS chemical biology 19 (2), 254-265, 2024 | 6 | 2024 |
White matter damage and degeneration in traumatic brain injury RC Armstrong, GM Sullivan, DP Perl, JD Rosarda, KL Radomski Trends in neurosciences 47 (9), 677-692, 2024 | 3 | 2024 |
Mapping stress-responsive signaling pathways induced by mitochondrial proteostasis perturbations N Madrazo, Z Khattar, ET Powers, JD Rosarda, RL Wiseman Molecular Biology of the Cell 35 (5), ar74, 2024 | 2 | 2024 |
Pharmacologic targeting of PDIA1 inhibits NLRP3 Inflammasome assembly and activation JD Rosarda, CR Stanton, EB Chen, MJ Bollong, RL Wiseman Israel Journal of Chemistry, e202300125, 2023 | 2 | 2023 |
Metabolically activated proteostasis regulators that protect against erastin-induced ferroptosis GM Kline, N Madrazo, CM Cole, M Pannikkat, MJ Bollong, JD Rosarda, ... RSC Chemical Biology 5 (9), 866-876, 2024 | 1 | 2024 |
Pharmacologic Activation of an Integrated Stress Response Kinase Promotes Mitochondrial Remodeling V Perea, KR Baron, V Dolina, G Aviles, JD Rosarda, X Guo, M Kampmann, ... bioRxiv, 2023.03. 11.532186, 2023 | | 2023 |
Deoxysphingolipids mediate toxicity though the Unfolded Protein Response (UPR) KT Eade, J Rosarda, S Giles, S Harkins-Perry, RL Wiseman, ... Investigative Ophthalmology & Visual Science 63 (7), 2436–F0380-2436–F0380, 2022 | | 2022 |
Amyloidogenic Proteins Drive Hepatic Proteostasis Remodeling in an Induced Pluripotent Stem Cell Model of Systemic Amyloid Disease RM Giadone, DC Liberti, TM Matte, JD Rosarda, C Torres-Arancivia, ... bioRxiv, 358515, 2018 | | 2018 |
Sabrina Ghosh, Jolene K. Diedrich, 3 Sandra Pankow, 3 Nicholas Skvir, JC Jean, John R. Yates III, 3 Andrew A. Wilson, Lawreen H. Connors, 2 Darrell N. Kotton, R. Luke Wiseman … RM Giadone, DC Liberti, TM Matte, JD Rosarda, C Torres-Arancivia | | |