Genome sequencing in microfabricated high-density picolitre reactors M Margulies, M Egholm, WE Altman, S Attiya, JS Bader, LA Bemben, ... Nature 437 (7057), 376-380, 2005 | 10691 | 2005 |
An integrated semiconductor device enabling non-optical genome sequencing JM Rothberg, W Hinz, TM Rearick, J Schultz, W Mileski, M Davey, ... Nature 475 (7356), 348-352, 2011 | 2967 | 2011 |
Methods of amplifying and sequencing nucleic acids JH Leamon, KL Lohman, JM Rothberg, MP Weiner US Patent 7,323,305, 2008 | 1357 | 2008 |
Methods and apparatus for measuring analytes JM Rothberg, W Hinz, JF Davidson, AM Van Oijen, JH Leamon, M Huber US Patent App. 12/474,897, 2010 | 1144 | 2010 |
Bead emulsion nucleic acid amplification J Berka, YJ Chen, JH Leamon, S Lefkowitz, KL Lohman, VB Makhijani, ... US Patent 7,842,457, 2010 | 857* | 2010 |
The development and impact of 454 sequencing JM Rothberg, JH Leamon Nature biotechnology 26 (10), 1117-1124, 2008 | 789 | 2008 |
Methods of amplifying and sequencing nucleic acids JH Leamon, KE McDade, JM Fierro, JR Knight, J Charumilind, ... US Patent 7,575,865, 2009 | 517 | 2009 |
High-throughput quantitative polymerase chain reaction in picoliter droplets MM Kiss, L Ortoleva-Donnelly, NR Beer, J Warner, CG Bailey, BW Colston, ... Analytical chemistry 80 (23), 8975-8981, 2008 | 500 | 2008 |
Nucleic acid amplification with continuous flow emulsion JR Nobile, WL Lee, JH Leamon US Patent 7,927,797, 2011 | 499 | 2011 |
Scaffolded nucleic acid polymer particles and methods of making and using W Hinz, J Leamon, D Light, J Rothberg US Patent 8,574,835, 2013 | 492 | 2013 |
Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing RK Thomas, E Nickerson, JF Simons, PA Jänne, T Tengs, Y Yuza, ... Nature medicine 12 (7), 852-855, 2006 | 429 | 2006 |
Method for preparing single-stranded DNA libraries G Costa, J Leamon, J Rothberg, M Weiner US Patent App. 10/767,894, 2004 | 400 | 2004 |
Whole genome analysis of genetic alterations in small DNA samples using hyperbranched strand displacement amplification and array–CGH JM Lage, JH Leamon, T Pejovic, S Hamann, M Lacey, D Dillon, ... Genome research 13 (2), 294-307, 2003 | 396 | 2003 |
Assessment of whole genome amplification-induced bias through high-throughput, massively parallel whole genome sequencing R Pinard, A de Winter, GJ Sarkis, MB Gerstein, KR Tartaro, RN Plant, ... BMC genomics 7, 1-21, 2006 | 389 | 2006 |
A massively parallel PicoTiterPlate™ based platform for discrete picoliter‐scale polymerase chain reactions JH Leamon, WL Lee, KR Tartaro, JR Lanza, GJ Sarkis, AD DeWinter, ... Electrophoresis 24 (21), 3769-3777, 2003 | 371 | 2003 |
Double ended sequencing YJ Chen, JH Leamon, KL Lohman, MT Ronan, JM Rothberg, ... US Patent 7,244,567, 2007 | 351 | 2007 |
Methods of amplifying and sequencing nucleic acids JH Leamon, KL Lohman, JM Rothberg, MP Weiner US Patent 8,790,876, 2014 | 343 | 2014 |
Methods for sequencing individual nucleic acids under tension JM Rothberg, JH Leamon, JF Davidson, AM Van Oijen, W Hinz, M Davey, ... US Patent App. 12/319,140, 2010 | 320 | 2010 |
Paired end sequencing J Berka, Z Chen, M Egholm, BC Godwin, SK Hutchison, JH Leamon, ... US Patent 7,601,499, 2009 | 308 | 2009 |
Methods and compositions for multiplex PCR J Leamon, M Andersen, M Thornton US Patent 9,957,558, 2018 | 245 | 2018 |