The Crohn’s disease risk factor IRGM limits NLRP3 inflammasome activation by impeding its assembly and by mediating its selective autophagy S Mehto, KK Jena, P Nath, S Chauhan, SP Kolapalli, SK Das, PK Sahoo, ... Molecular cell 73 (3), 429-445. e7, 2019 | 169 | 2019 |
TRIM16 controls assembly and degradation of protein aggregates by modulating the p62‐NRF2 axis and autophagy KK Jena, SP Kolapalli, S Mehto, P Nath, B Das, PK Sahoo, A Ahad, ... The EMBO journal 37 (18), e98358, 2018 | 100 | 2018 |
Autoimmunity gene IRGM suppresses cGAS‐STING and RIG‐I‐MAVS signaling to control interferon response KK Jena, S Mehto, P Nath, NR Chauhan, R Sahu, K Dhar, SK Das, ... EMBO reports 21 (9), e50051, 2020 | 50 | 2020 |
IRGM restrains NLRP3 inflammasome activation by mediating its SQSTM1/p62-dependent selective autophagy S Mehto, S Chauhan, KK Jena, NR Chauhan, P Nath, R Sahu, K Dhar, ... Autophagy 15 (9), 1645-1647, 2019 | 38 | 2019 |
IRGM links autoimmunity to autophagy P Nath, KK Jena, S Mehto, NR Chauhan, R Sahu, K Dhar, K Srinivas, ... Autophagy 17 (2), 578-580, 2021 | 23 | 2021 |
TRIM16 governs the biogenesis and disposal of stress-induced protein aggregates to evade cytotoxicity: implication for neurodegeneration and cancer KK Jena, S Mehto, SP Kolapalli, P Nath, R Sahu, NR Chauhan, PK Sahoo, ... Autophagy 15 (5), 924-926, 2019 | 22 | 2019 |
Inhibition of IRGM establishes a robust antiviral immune state to restrict pathogenic viruses P Nath, NR Chauhan, KK Jena, A Datey, ND Kumar, S Mehto, S De, ... EMBO reports 22 (11), e52948, 2021 | 17 | 2021 |
TRIM16 employs NRF2, ubiquitin system and aggrephagy for safe disposal of stress-induced misfolded proteins KK Jena, S Mehto, SP Kolapalli, P Nath, S Chauhan, S Chauhan Cell Stress 2 (12), 365, 2018 | 7 | 2018 |
Autoimmunity risk gene IRGM is a master negative regulator of interferon response by controlling the activation of cGAS-STING and RIG-I-MAVS signaling pathways KK Jena, S Mehto, P Nath, NR Chauhan, R Sahu, TK Nayak, SK Das, ... bioRxiv, 815506, 2019 | 1 | 2019 |
Understanding the Role of IRGM in Regulating Innate Immunity P Nath Bhubaneswar, 0 | | |