Recruitment of HIF-1α and HIF-2α to common target genes is differentially regulated in neuroblastoma: HIF-2α promotes an aggressive phenotype L Holmquist-Mengelbier, E Fredlund, T Löfstedt, R Noguera, S Navarro, ... Cancer cell 10 (5), 413-423, 2006 | 882 | 2006 |
Osteopontin-CD44 signaling in the glioma perivascular niche enhances cancer stem cell phenotypes and promotes aggressive tumor growth A Pietras, AM Katz, EJ Ekström, B Wee, JJ Halliday, KL Pitter, JL Werbeck, ... Cell stem cell 14 (3), 357-369, 2014 | 533 | 2014 |
Hypoxia inducible factor-2alpha in cancer T Lofstedt, E Fredlund, L Holmquist-Mengelbier, A Pietras, M Ovenberger, ... CELL CYCLE-LANDES BIOSCIENCE- 6 (8), 919, 2007 | 244 | 2007 |
Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo J Sjölund, M Johansson, S Manna, C Norin, A Pietras, S Beckman, ... The Journal of clinical investigation 118 (1), 217-228, 2008 | 218 | 2008 |
HIF-2α maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells A Pietras, LM Hansford, AS Johnsson, E Bridges, J Sjölund, D Gisselsson, ... Proceedings of the National Academy of Sciences 106 (39), 16805-16810, 2009 | 174 | 2009 |
High levels of HIF‐2α highlight an immature neural crest‐like neuroblastoma cell cohort located in a perivascular niche A Pietras, D Gisselsson, I Øra, R Noguera, S Beckman, S Navarro, ... The Journal of pathology 214 (4), 482-488, 2008 | 142 | 2008 |
Cancer stem cells in tumor heterogeneity A Pietras Advances in cancer research 112, 255-281, 2011 | 114 | 2011 |
CD44 interacts with HIF-2α to modulate the hypoxic phenotype of perinecrotic and perivascular glioma cells E Johansson, ES Grassi, V Pantazopoulou, B Tong, D Lindgren, TJ Berg, ... Cell reports 20 (7), 1641-1653, 2017 | 103 | 2017 |
HIF-1α and HIF-2α Are Differentially Regulated In vivo in Neuroblastoma: High HIF-1α Correlates Negatively to Advanced Clinical Stage and Tumor Vascularization R Noguera, E Fredlund, M Piqueras, A Pietras, S Beckman, S Navarro, ... Clinical cancer research 15 (23), 7130-7136, 2009 | 101 | 2009 |
Recruited cells can become transformed and overtake PDGF-induced murine gliomas in vivo during tumor progression EI Fomchenko, JD Dougherty, KY Helmy, AM Katz, A Pietras, C Brennan, ... PloS one 6 (7), e20605, 2011 | 96 | 2011 |
The HIF-2α-driven pseudo-hypoxic phenotype in tumor aggressiveness, differentiation, and vascularization A Pietras, AS Johnsson, S Påhlman Diverse Effects of Hypoxia on Tumor Progression, 1-20, 2010 | 80 | 2010 |
JAG2 induction in hypoxic tumor cells alters Notch signaling and enhances endothelial cell tube formation A Pietras, K von Stedingk, D Lindgren, S Påhlman, H Axelson Molecular Cancer Research 9 (5), 626, 2011 | 74 | 2011 |
ABCG2 regulates self-renewal and stem cell marker expression but not tumorigenicity or radiation resistance of glioma cells B Wee, A Pietras, T Ozawa, E Bazzoli, O Podlaha, C Antczak, ... Scientific reports 6 (1), 25956, 2016 | 61 | 2016 |
Arsenic trioxide is highly cytotoxic to small cell lung carcinoma cells HM Pettersson, A Pietras, M Munksgaard Persson, J Karlsson, ... Molecular cancer therapeutics 8 (1), 160-170, 2009 | 60 | 2009 |
Radiotherapy-induced remodeling of the tumor microenvironment by stromal cells TJ Berg, A Pietras Seminars in Cancer Biology 86, 846-856, 2022 | 37 | 2022 |
Arsenic trioxide and neuroblastoma cytotoxicity HM Pettersson, J Karlsson, A Pietras, I Øra, S Påhlman Journal of bioenergetics and biomembranes 39 (1), 35-41, 2007 | 34 | 2007 |
The irradiated brain microenvironment supports glioma stemness and survival via astrocyte-derived transglutaminase 2 TJ Berg, C Marques, V Pantazopoulou, E Johansson, K Von Stedingk, ... Cancer research 81 (8), 2101-2115, 2021 | 33 | 2021 |
Hypoxia-induced release, nuclear translocation, and signaling activity of a DLK1 intracellular fragment in glioma ES Grassi, V Pantazopoulou, A Pietras Oncogene 39 (20), 4028-4044, 2020 | 31 | 2020 |
Arsenic trioxide-induced neuroblastoma cell death is accompanied by proteolytic activation of nuclear Bax J Karlsson, A Pietras, S Beckman, HM Pettersson, C Larsson, S Påhlman Oncogene 26 (42), 6150-6159, 2007 | 22 | 2007 |
Emerging roles of DLK1 in the stem cell niche and cancer stemness ES Grassi, A Pietras Journal of Histochemistry & Cytochemistry 70 (1), 17-28, 2022 | 20 | 2022 |