Development of selective histone deacetylase 6 (HDAC6) degraders recruiting von Hippel–Lindau (VHL) E3 ubiquitin ligase K Yang, H Wu, Z Zhang, ED Leisten, X Nie, B Liu, Z Wen, J Zhang, ... ACS Medicinal Chemistry Letters 11 (4), 575-581, 2020 | 91 | 2020 |
A cell-based target engagement assay for the identification of cereblon E3 ubiquitin ligase ligands and their application in HDAC6 degraders K Yang, Y Zhao, X Nie, H Wu, B Wang, CM Almodovar-Rivera, H Xie, ... Cell chemical biology 27 (7), 866-876. e8, 2020 | 62 | 2020 |
In silico modeling and scoring of PROTAC-mediated ternary complex poses J Liao, X Nie, IC Unarta, SS Ericksen, W Tang Journal of Medicinal Chemistry 65 (8), 6116-6132, 2022 | 36 | 2022 |
A platform for the rapid synthesis of proteolysis targeting chimeras (Rapid-TAC) under miniaturized conditions L Guo, Y Zhou, X Nie, Z Zhang, Z Zhang, C Li, T Wang, W Tang European journal of medicinal chemistry 236, 114317, 2022 | 27 | 2022 |
Development of selective FGFR1 degraders using a rapid synthesis of proteolysis targeting Chimera (Rapid-TAC) platform L Guo, J Liu, X Nie, T Wang, Z Ma, D Yin, W Tang Bioorganic & Medicinal Chemistry Letters 75, 128982, 2022 | 8 | 2022 |
Development of Phenyl‐substituted Isoindolinone‐and Benzimidazole‐type Cereblon Ligands for Targeted Protein Degradation X Nie, Y Zhao, H Tang, Z Zhang, J Liao, CM Almodovar‐Rivera, ... ChemBioChem 25 (4), e202300685, 2024 | 1 | 2024 |
Evaluation of the binding affinity of E3 ubiquitin ligase ligands by cellular target engagement and in-cell ELISA assay K Yang, Y Zhou, BL Roberts, X Nie, W Tang STAR protocols 2 (1), 100288, 2021 | 1 | 2021 |
Supporting Information In Silico Modeling and Scoring of PROTAC-mediated Ternary Complex Poses J Liao, X Nie, IC Unarta, SS Ericksen, W Tang, SS Ericksen, W Tang | | |