关注
Sarah K. Denny
Sarah K. Denny
Scribe Therapeutics
在 scribetx.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Structured nucleosome fingerprints enable high-resolution mapping of chromatin architecture within regulatory regions
AN Schep, JD Buenrostro, SK Denny, K Schwartz, G Sherlock, ...
Genome research 25 (11), 1757-1770, 2015
3792015
Nfib promotes metastasis through a widespread increase in chromatin accessibility
SK Denny, D Yang, CH Chuang, JJ Brady, JS Lim, BM Grüner, SH Chiou, ...
Cell 166 (2), 328-342, 2016
3612016
Variable chromatin structure revealed by in situ spatially correlated DNA cleavage mapping
VI Risca, SK Denny, AF Straight, WJ Greenleaf
Nature 541 (7636), 237-241, 2017
1652017
Intertumoral heterogeneity in SCLC is influenced by the cell type of origin
D Yang, SK Denny, PG Greenside, AC Chaikovsky, JJ Brady, Y Ouadah, ...
Cancer discovery 8 (10), 1316-1331, 2018
1372018
High-throughput investigation of diverse junction elements in RNA tertiary folding
SK Denny, N Bisaria, JD Yesselman, R Das, D Herschlag, WJ Greenleaf
Cell 174 (2), 377-390. e20, 2018
932018
A quantitative and predictive model for RNA binding by human Pumilio proteins
I Jarmoskaite, SK Denny, PP Vaidyanathan, WR Becker, JOL Andreasson, ...
Molecular cell 74 (5), 966-981. e18, 2019
732019
Sequence-dependent RNA helix conformational preferences predictably impact tertiary structure formation
JD Yesselman, SK Denny, N Bisaria, D Herschlag, WJ Greenleaf, R Das
Proceedings of the National Academy of Sciences 116 (34), 16847-16855, 2019
412019
Linking RNA sequence, structure, and function on massively parallel high-throughput sequencers
SK Denny, WJ Greenleaf
Cold Spring Harbor Perspectives in Biology 11 (10), a032300, 2019
242019
Multifaceted role for p53 in pancreatic cancer suppression
SS Mello, BM Flowers, PK Mazur, JJ Lee, F Müller, SK Denny, S Ferreira, ...
Proceedings of the National Academy of Sciences 120 (10), e2211937120, 2023
222023
Intertumoral heterogeneity in SCLC is influenced by the cell type of origin. Cancer Discov. 2018; 8: 1316–1331. doi: 10.1158/2159-8290
D Yang, SK Denny, PG Greenside, AC Chaikovsky, JJ Brady, Y Ouadah, ...
CD-17-0987.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0
19
High-throughput dissection of the thermodynamic and conformational properties of a ubiquitous class of RNA tertiary contact motifs
SL Bonilla, SK Denny, JH Shin, A Alvarez-Buylla, WJ Greenleaf, ...
Proceedings of the National Academy of Sciences 118 (33), e2109085118, 2021
132021
Quantitative high-throughput tests of ubiquitous RNA secondary structure prediction algorithms via RNA/protein binding
WR Becker, I Jarmoskaite, K Kappel, PP Vaidyanathan, SK Denny, R Das, ...
bioRxiv, 571588, 2019
102019
RNA tertiary structure energetics predicted by an ensemble model of the RNA double helix
JD Yesselman, SK Denny, N Bisaria, D Herschlag, WJ Greenleaf, R Das
BioRxiv, 341107, 2018
82018
A comprehensive thermodynamic model for RNA binding by the Saccharomyces cerevisiae Pumilio protein PUF4
C Sadée, LD Hagler, WR Becker, I Jarmoskaite, PP Vaidyanathan, ...
Nature Communications 13 (1), 4522, 2022
62022
Dissecting the energetic architecture within an RNA tertiary structural motif via high-throughput thermodynamic measurements
JH Shin, SL Bonilla, SK Denny, WJ Greenleaf, D Herschlag
Proceedings of the National Academy of Sciences 120 (11), e2220485120, 2023
42023
Engineered proteins
B Oakes, S Higgins, H Spinner, S Denny, BT Staahl, K Taylor, K Baney, ...
US Patent 11,560,555, 2023
42023
Engineered casx systems
B Oakes, S Higgins, H Spinner, S Denny, BT Staahl, K Taylor, K Baney, ...
US Patent App. 17/542,219, 2022
42022
Compositions and methods for the targeting of SOD1
B Oakes, S Higgins, H Spinner, S Denny, BT Staahl, K Taylor, K Baney, ...
US Patent 11,613,742, 2023
32023
Compositions and methods for the targeting of pcsk9
B Oakes, S Higgins, H Spinner, S Denny, BT Staahl, K Taylor, K Baney, ...
US Patent App. 17/791,130, 2023
22023
Compositions and methods for use in immunotherapy
B Oakes, S Higgins, H Spinner, S Denny, BT Staahl, K Taylor, K Baney, ...
US Patent App. 17/641,404, 2023
22023
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