Molecular signatures of G-protein-coupled receptors AJ Venkatakrishnan, X Deupi, G Lebon, CG Tate, GF Schertler, MM Babu Nature 494 (7436), 185-194, 2013 | 1738 | 2013 |
Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation G Lebon, T Warne, PC Edwards, K Bennett, CJ Langmead, AGW Leslie, ... Nature 474 (7352), 521-525, 2011 | 1012 | 2011 |
Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region AJ Venkatakrishnan, X Deupi, G Lebon, FM Heydenreich, T Flock, ... Nature 536 (7617), 484-487, 2016 | 321 | 2016 |
Thermostabilisation of an agonist-bound conformation of the human adenosine A2A receptor G Lebon, K Bennett, A Jazayeri, CG Tate Journal of molecular biology 409 (3), 298-310, 2011 | 156 | 2011 |
Molecular determinants of CGS21680 binding to the human adenosine A2A receptor G Lebon, PC Edwards, AGW Leslie, CG Tate Molecular pharmacology 87 (6), 907-915, 2015 | 155 | 2015 |
Agonist-bound structures of G protein-coupled receptors G Lebon, T Warne, CG Tate Current opinion in structural biology 22 (4), 482-490, 2012 | 115 | 2012 |
A mutagenesis and screening strategy to generate optimally thermostabilized membrane proteins for structural studies F Magnani, MJ Serrano-Vega, Y Shibata, S Abdul-Hussein, G Lebon, ... Nature protocols 11 (8), 1554-1571, 2016 | 105 | 2016 |
Human Adenosine A2A Receptor: Molecular Mechanism of Ligand Binding and Activation B Carpenter, G Lebon Frontiers in pharmacology 8, 898, 2017 | 99 | 2017 |
Outrunning free radicals in room-temperature macromolecular crystallography RL Owen, D Axford, JE Nettleship, RJ Owens, JI Robinson, AW Morgan, ... Acta Crystallographica Section D: Biological Crystallography 68 (7), 810-818, 2012 | 95 | 2012 |
Pharmacology and structure of isolated conformations of the adenosine A2A receptor define ligand efficacy KA Bennett, B Tehan, G Lebon, CG Tate, M Weir, FH Marshall, ... Molecular pharmacology 83 (5), 949-958, 2013 | 85 | 2013 |
Mutagenic mapping suggests a novel binding mode for selective agonists of M1 muscarinic acetylcholine receptors G Lebon, CJ Langmead, BG Tehan, EC Hulme Molecular pharmacology 75 (2), 331-341, 2009 | 62 | 2009 |
Piezo1 is required for outflow tract and aortic valve development. A Faucherre, HM ou Maati, N Nasr, A Pinard, A Theron, G Odelin, ... Journal of molecular and cellular cardiology 143, 51-62, 2020 | 60 | 2020 |
Competition on nitrocellulose-immobilized antibody arrays: from bacterial protein binding assay to protein profiling in breast cancer cells G Yeretssian, M Lecocq, G Lebon, HC Hurst, V Sakanyan Molecular & Cellular Proteomics 4 (5), 605-617, 2005 | 44 | 2005 |
Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations C Nasrallah, G Cannone, J Briot, K Rottier, AE Berizzi, CY Huang, ... Cell reports 36 (9), 2021 | 37 | 2021 |
A bacterial toxin with analgesic properties: hyperpolarization of DRG neurons by mycolactone OR Song, HB Kim, S Jouny, I Ricard, A Vandeputte, N Deboosere, ... Toxins 9 (7), 227, 2017 | 34 | 2017 |
Mutant proteins and methods for producing them SA Jazayeri-Dezfuly, GP Lebon, FH Marshall, CG Tate, N Robertson US Patent 8,703,915, 2014 | 31 | 2014 |
Direct coupling of detergent purified human mGlu5 receptor to the heterotrimeric G proteins Gq and Gs C Nasrallah, K Rottier, R Marcellin, V Compan, J Font, A Llebaria, JP Pin, ... Scientific Reports 8 (1), 4407, 2018 | 23 | 2018 |
Pi sampling: a methodical and flexible approach to initial macromolecular crystallization screening F Gorrec, CM Palmer, G Lebon, T Warne Acta Crystallographica Section D: Biological Crystallography 67 (5), 463-470, 2011 | 21 | 2011 |
Inhibition of the angiotensin II type 2 receptor AT2R is a novel therapeutic strategy for glioblastoma R Perryman, A Renziehausen, H Shaye, AD Kostagianni, AD Tsiailanis, ... Proceedings of the National Academy of Sciences 119 (32), e2116289119, 2022 | 12 | 2022 |
Les récepteurs couplés aux protéines G dans la lumière G Lebon, CG Tate médecine/sciences 28 (10), 876-882, 2012 | 9 | 2012 |