| Visualization of NRAS RNA G-Quadruplex Structures in Cells with an Engineered Fluorogenic Hybridization Probe SB Chen, MH Hu, GC Liu, J Wang, TM Ou, LQ Gu, ZS Huang, JH Tan Journal of the American Chemical Society 138 (33), 10382-10385, 2016 | 123 | 2016 |
| Discovery of a New Four-Leaf Clover-Like Ligand as a Potent c-MYC Transcription Inhibitor Specifically Targeting the Promoter G-Quadruplex MH Hu, YQ Wang, ZY Yu, LN Hu, TM Ou, SB Chen, ZS Huang, JH Tan Journal of medicinal chemistry 61 (6), 2447-2459, 2018 | 97 | 2018 |
| Specific targeting of telomeric multimeric G-quadruplexes by a new triaryl-substituted imidazole MH Hu, SB Chen, B Wang, TM Ou, LQ Gu, JH Tan, ZS Huang Nucleic acids research 45 (4), 1606-1618, 2017 | 89 | 2017 |
| New substituted quinoxalines inhibit triple-negative breast cancer by specifically downregulating the c-MYC transcription MH Hu, TY Wu, Q Huang, G Jin Nucleic acids research 47 (20), 10529-10542, 2019 | 82 | 2019 |
| Discovery of Novel 11-Triazole Substituted Benzofuro[3,2-b]quinolone Derivatives as c-myc G-Quadruplex Specific Stabilizers via Click Chemistry DY Zeng, GT Kuang, SK Wang, W Peng, SL Lin, Q Zhang, XX Su, MH Hu, ... Journal of Medicinal Chemistry 60 (13), 5407-5423, 2017 | 81 | 2017 |
| Discovery of a new fluorescent light-up probe specific to parallel G-quadruplexes SB Chen, WB Wu, MH Hu, TM Ou, LQ Gu, JH Tan, ZS Huang Chemical Communications 50 (81), 12173-12176, 2014 | 51 | 2014 |
| Synthesis and biological evaluation of benzo [a] phenazine derivatives as a dual inhibitor of topoisomerase I and II ST Zhuo, CY Li, MH Hu, SB Chen, PF Yao, SL Huang, TM Ou, JH Tan, ... Organic & Biomolecular Chemistry 11 (24), 3989-4005, 2013 | 51 | 2013 |
| Development of a Smart Fluorescent Sensor That Specifically Recognizes the c-MYC G-Quadruplex MH Hu, J Zhou, WH Luo, SB Chen, ZS Huang, R Wu, JH Tan Analytical chemistry 91 (3), 2480-2487, 2019 | 46 | 2019 |
| Development of a highly sensitive fluorescent light-up probe for G-quadruplexes MH Hu, SB Chen, RJ Guo, TM Ou, ZS Huang, JH Tan Analyst 140 (13), 4616-4625, 2015 | 34 | 2015 |
| A new application of click chemistry in situ: development of fluorescent probe for specific G-quadruplex topology MH Hu, X Chen, SB Chen, TM Ou, M Yao, LQ Gu, ZS Huang, JH Tan Scientific Reports 5 (1), 17202, 2015 | 31 | 2015 |
| Molecular engineering of a near-infrared fluorescent ligand for tracking mitochondrial DNA G-quadruplexes MH Hu Analytica Chimica Acta 1169, 338600, 2021 | 25 | 2021 |
| Accurate high-throughput identification of parallel G-quadruplex topology by a new tetraaryl-substituted imidazole MH Hu, SB Chen, YQ Wang, YM Zeng, TM Ou, D Li, LQ Gu, ZS Huang, ... Biosensors and Bioelectronics 83, 77-84, 2016 | 25 | 2016 |
| New Dibenzoquinoxalines Inhibit Triple-Negative Breast Cancer Growth by Dual Targeting of Topoisomerase 1 and the c-MYC G-Quadruplex MH Hu, JH Lin Journal of Medicinal Chemistry 64 (10), 6720-6729, 2021 | 24 | 2021 |
| Dimeric aryl-substituted imidazoles may inhibit ALT cancer by targeting the multimeric G-quadruplex in telomere MH Hu, XT Lin, B Liu, JH Tan European Journal of Medicinal Chemistry 186, 111891, 2020 | 23 | 2020 |
| Oxaliplatin-based platinum (IV) prodrug bearing toll-like receptor 7 agonist for enhanced immunochemotherapy L Tang, D Cai, M Qin, S Lu, MH Hu, S Ruan, G Jin, Z Wang ACS omega 5 (1), 726-734, 2019 | 23 | 2019 |
| Development of an engineered carbazole/thiazole orange conjugating probe for G-quadruplexes MH Hu, RJ Guo, SB Chen, ZS Huang, JH Tan Dyes and Pigments 137, 191-199, 2017 | 23 | 2017 |
| A drug-like imidazole-benzothiazole conjugate inhibits malignant melanoma by stabilizing the c-MYC G-quadruplex TY Wu, Q Huang, ZS Huang, MH Hu, JH Tan Bioorganic Chemistry 99, 103866, 2020 | 22 | 2020 |
| Development of a near-infrared fluorescent ligand that visualizes and stabilizes G-quadruplexes by decorating the triphenylamine scaffold X Wang, BY Yu, JH Lin, Y Yan, MH Hu Sensors and Actuators B: Chemical 330, 129391, 2021 | 21 | 2021 |
| Natural aromatic compounds as scaffolds to develop selective G-quadruplex ligands: from previously reported berberine derivatives to new palmatine analogues M Franceschin, L Cianni, M Pitorri, E Micheli, S Cacchione, C Frezza, ... Molecules 23 (6), 1423, 2018 | 20 | 2018 |
| Tuning the selectivity of a commercial cyanine nucleic acid dye for preferential sensing of hybrid telomeric G-quadruplex DNA YQ Wang, MH Hu, RJ Guo, SB Chen, ZS Huang, JH Tan Sensors and Actuators B: Chemical 266, 187-194, 2018 | 19 | 2018 |
