Membrane transporters in drug development Nature reviews Drug discovery 9 (3), 215-236, 2010 | 3548 | 2010 |
Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily PI Mackenzie, KW Bock, B Burchell, C Guillemette, S Ikushiro, T Iyanagi, ... Pharmacogenetics and genomics 15 (10), 677-685, 2005 | 981 | 2005 |
Pharmacogenomics of human UDP-glucuronosyltransferase enzymes C Guillemette The pharmacogenomics journal 3 (3), 136-158, 2003 | 568 | 2003 |
Common human UGT1A polymorphisms and the altered metabolism of irinotecan active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38) JF Gagné, V Montminy, P Belanger, K Journault, G Gaucher, ... Molecular pharmacology 62 (3), 608-617, 2002 | 425 | 2002 |
Glucuronidation and the UDP-glucuronosyltransferases in health and disease PG Wells, PI Mackenzie, JR Chowdhury, C Guillemette, PA Gregory, ... Drug metabolism and disposition 32 (3), 281-290, 2004 | 322 | 2004 |
Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 and association with breast cancer among African Americans C Guillemette, RC Millikan, B Newman, DE Housman Cancer research 60 (4), 950-956, 2000 | 281 | 2000 |
Direct haplotyping of kilobase-size DNA using carbon nanotube probes AT Woolley, C Guillemette, C Li Cheung, DE Housman, CM Lieber Nature biotechnology 18 (7), 760-763, 2000 | 265 | 2000 |
The main role of UGT1A9 in the hepatic metabolism of mycophenolic acid and the effects of naturally occurring variants O Bernard, C Guillemette Drug Metabolism and Disposition 32 (8), 775-778, 2004 | 256 | 2004 |
Specificity and regioselectivity of the conjugation of estradiol, estrone, and their catecholestrogen and methoxyestrogen metabolites by human uridine diphospho … J Lépine, O Bernard, M Plante, B Têtu, G Pelletier, F Labrie, A Bélanger, ... The journal of clinical endocrinology & metabolism 89 (10), 5222-5232, 2004 | 246 | 2004 |
Novel functional polymorphisms in the UGT1A7 and UGT1A9 glucuronidating enzymes in Caucasian and African-American subjects and their impact on the metabolism of 7-ethyl-10 … L Villeneuve, H Girard, LC Fortier, JF Gagné, C Guillemette Journal of Pharmacology and Experimental Therapeutics 307 (1), 117-128, 2003 | 235 | 2003 |
Structural heterogeneity at the UDP-glucuronosyltransferase 1 locus: functional consequences of three novel missense mutations in the human UGT1A7 gene C Guillemette, JK Ritter, DJ Auyeung, FK Kessler, DE Housman Pharmacogenetics and Genomics 10 (7), 629-644, 2000 | 220 | 2000 |
The impact of UGT1A8, UGT1A9, and UGT2B7 genetic polymorphisms on the pharmacokinetic profile of mycophenolic acid after a single oral dose in healthy volunteers E Levesque, R Delage, MO Benoit‐Biancamano, P Caron, O Bernard, ... Clinical Pharmacology & Therapeutics 81 (3), 392-400, 2007 | 203 | 2007 |
Tobacco carcinogen-detoxifying enzyme UGT1A7 and its association with orolaryngeal cancer risk Z Zheng, JY Park, C Guillemette, SP Schantz, P Lazarus Journal of the National Cancer Institute 93 (18), 1411-1418, 2001 | 198 | 2001 |
Identification of common polymorphisms in the promoter of the UGT1A9 gene: evidence that UGT1A9 protein and activity levels are strongly genetically controlled in the liver H Girard, O Bernard, LC Fortier, L Villeneuve, Q Hao, DJ Greenblatt, ... Pharmacogenetics and Genomics 14 (8), 501-515, 2004 | 197 | 2004 |
Three-dimensional culture and cAMP signaling promote the maturation of human pluripotent stem cell-derived hepatocytes S Ogawa, J Surapisitchat, C Virtanen, M Ogawa, M Niapour, KS Sugamori, ... Development 140 (15), 3285-3296, 2013 | 194 | 2013 |
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for UGT1A1 and Atazanavir Prescribing RS Gammal, MH Court, CE Haidar, OF Iwuchukwu, AH Gaur, M Alvarellos, ... Clinical Pharmacology & Therapeutics 99 (4), 363-369, 2016 | 188 | 2016 |
UGT genomic diversity: beyond gene duplication C Guillemette, E Lévesque, M Harvey, J Bellemare, V Menard Drug metabolism reviews 42 (1), 24-44, 2010 | 186 | 2010 |
Glucuronidation of the antiretroviral drug efavirenz by UGT2B7 and an in vitro investigation of drug-drug interaction with zidovudine AS Bélanger, P Caron, M Harvey, PA Zimmerman, RK Mehlotra, ... Drug Metabolism and Disposition 37 (9), 1793-1796, 2009 | 177 | 2009 |
The UDP-glucuronosyltransferase 1A9 enzyme is a peroxisome proliferator-activated receptor α and γ target gene O Barbier, L Villeneuve, V Bocher, C Fontaine, IP Torra, C Duhem, ... Journal of Biological Chemistry 278 (16), 13975-13983, 2003 | 177 | 2003 |
Pharmacogenomics of human uridine diphospho‐glucuronosyltransferases and clinical implications C Guillemette, É Lévesque, M Rouleau Clinical Pharmacology & Therapeutics 96 (3), 324-339, 2014 | 175 | 2014 |