| Post-translational modifications of Hsp90 and translating the chaperone code SJ Backe, RA Sager, MR Woodford, AM Makedon, M Mollapour Journal of Biological Chemistry 295 (32), 11099-11117, 2020 | 146 | 2020 |
| Tumor suppressor Tsc1 is a new Hsp90 co‐chaperone that facilitates folding of kinase and non‐kinase clients MR Woodford, RA Sager, E Marris, DM Dunn, AR Blanden, RL Murphy, ... The EMBO journal 36 (24), 3650-3665, 2017 | 80 | 2017 |
| Chemical perturbation of oncogenic protein folding: from the prediction of locally unstable structures to the design of disruptors of Hsp90–client interactions A Paladino, MR Woodford, SJ Backe, RA Sager, P Kancherla, ... Chemistry–A European Journal 26 (43), 9459-9465, 2020 | 52 | 2020 |
| Phosphorylation and ubiquitination regulate protein phosphatase 5 activity and its prosurvival role in kidney cancer N Dushukyan, DM Dunn, RA Sager, MR Woodford, DR Loiselle, ... Cell reports 21 (7), 1883-1895, 2017 | 44 | 2017 |
| Post-translational regulation of FNIP1 creates a rheostat for the molecular chaperone Hsp90 RA Sager, MR Woodford, SJ Backe, AM Makedon, AJ Baker-Williams, ... Cell reports 26 (5), 1344-1356. e5, 2019 | 40 | 2019 |
| Structure and function of the co-chaperone protein phosphatase 5 in cancer RA Sager, N Dushukyan, M Woodford, M Mollapour Cell Stress and Chaperones 25 (3), 383-394, 2020 | 27 | 2020 |
| The tumor suppressor folliculin inhibits lactate dehydrogenase A and regulates the Warburg effect MR Woodford, AJ Baker-Williams, RA Sager, SJ Backe, AR Blanden, ... Nature structural & molecular biology 28 (8), 662-670, 2021 | 24 | 2021 |
| Mutation of the co-chaperone Tsc1 in bladder cancer diminishes Hsp90 acetylation and reduces drug sensitivity and selectivity MR Woodford, M Hughes, RA Sager, SJ Backe, AJ Baker-Williams, ... Oncotarget 10 (56), 5824, 2019 | 19 | 2019 |
| A specialized Hsp90 co-chaperone network regulates steroid hormone receptor response to ligand SJ Backe, RA Sager, BR Regan, J Sit, LA Major, G Bratslavsky, ... Cell Reports 40 (2), 111039, 2022 | 18 | 2022 |
| Detecting posttranslational modifications of Hsp90 RA Sager, MR Woodford, L Neckers, M Mollapour Chaperones: Methods and Protocols, 209-219, 2018 | 18 | 2018 |
| Therapeutic potential of CDK4/6 inhibitors in renal cell carcinoma RA Sager, SJ Backe, E Ahanin, G Smith, I Nsouli, MR Woodford, ... Nature Reviews Urology 19 (5), 305-320, 2022 | 16 | 2022 |
| The mTOR independent function of Tsc1 and FNIPs RA Sager, MR Woodford, M Mollapour Trends in biochemical sciences 43 (12), 935-937, 2018 | 15 | 2018 |
| Fumarate hydratase as a therapeutic target in renal cancer P Kancherla, M Daneshvar, RA Sager, M Mollapour, G Bratslavsky Expert Opinion on Therapeutic Targets 24 (9), 923-936, 2020 | 14 | 2020 |
| Loss of Wave1 gene defines a subtype of lethal prostate cancer AG Sowalsky, R Sager, RJ Schaefer, G Bratslavsky, PP Pandolfi, SP Balk, ... Oncotarget 6 (14), 12383, 2015 | 14 | 2015 |
| Targeting extracellular Hsp90: A unique frontier against cancer RA Sager, F Khan, L Toneatto, SBD Votra, SJ Backe, MR Woodford, ... Frontiers in Molecular Biosciences 9, 982593, 2022 | 13 | 2022 |
| Sporadic renal angiomyolipoma in a patient with Birt-Hogg-Dubé: chaperones in pathogenesis RA Sager, MR Woodford, O Shapiro, M Mollapour, G Bratslavsky Oncotarget 9 (31), 22220, 2018 | 13 | 2018 |
| Genomic Profiles and Clinical Outcomes of Penile Squamous Cell Carcinoma With Elevated Tumor Mutational Burden A Necchi, PE Spiess, TC de Padua, R Li, P Grivas, RSP Huang, DI Lin, ... JAMA Network Open 6 (12), e2348002-e2348002, 2023 | 6 | 2023 |
| The role of heat shock protein-90 in the pathogenesis of birt-hogg-dubé and tuberous sclerosis complex syndromes MR Woodford, SJ Backe, RA Sager, D Bourboulia, G Bratslavsky, ... Urologic Oncology: Seminars and Original Investigations 39 (6), 322-326, 2021 | 6 | 2021 |
| Phosphorylation and ubiquitination regulate protein phosphatase 5 activity and its prosurvival role in kidney cancer. Cell Rep 21: 1883–1895 N Dushukyan, DM Dunn, RA Sager, MR Woodford, DR Loiselle, ... | 5 | 2017 |
| Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery SJ Backe, RA Sager, JA Heritz, LA Wengert, KA Meluni, X Aran-Guiu, ... Cell Reports 42 (7), 2023 | 4 | 2023 |
