| Structural basis for gene regulation by a B12-dependent photoreceptor M Jost, J Fernández-Zapata, MC Polanco, JM Ortiz-Guerrero, PYT Chen, ... Nature 526 (7574), 536-541, 2015 | 185 | 2015 |
| Molecular basis for allosteric specificity regulation in class Ia ribonucleotide reductase from Escherichia coli CM Zimanyi, PYT Chen, G Kang, MA Funk, CL Drennan eLife 5, e07141, 2016 | 77 | 2016 |
| Ancient plant-like terpene biosynthesis in corals I Burkhardt, T de Rond, PYT Chen, BS Moore Nature Chemical Biology 18 (6), 664-669, 2022 | 48 | 2022 |
| Structural basis for non-radical catalysis by TsrM, a radical SAM methylase HL Knox, PYT Chen, AJ Blaszczyk, A Mukherjee, TL Grove, EL Schwalm, ... Nature Chemical Biology 17, 485–491, 2021 | 45 | 2021 |
| X-ray crystallography–based structural elucidation of enzyme-bound intermediates along the 1‑deoxy‑d‑xylulose 5-phosphate synthase reaction coordinate PYT Chen, AA DeColli, CLF Meyers, CL Drennan Journal of Biological Chemistry 294 (33), 12405-12414, 2019 | 35 | 2019 |
| Binding site for coenzyme A revealed in the structure of pyruvate:ferredoxin oxidoreductase from Moorella thermoacetica PYT Chen, H Aman, M Can, SW Ragsdale, CL Drennan Proceedings of the National Academy of Sciences 115 (15), 3846-3851, 2018 | 30 | 2018 |
| A reverse TCA cycle 2-oxoacid:ferredoxin oxidoreductase that makes C-C bonds from CO2 PYT Chen, B Li, CL Drennan, SJ Elliott Joule 3 (2), 595-611, 2019 | 28 | 2019 |
| A structural phylogeny for understanding 2-oxoacid oxidoreductase function MI Gibson, PYT Chen, CL Drennan Current Opinion in Structural Biology 41, 54-61, 2016 | 25 | 2016 |
| Enzymatic assembly of the salinosporamide γ-lactam-β-lactone anticancer warhead KD Bauman, VV Shende, PYT Chen, DBB Trivella, TAM Gulder, ... Nature Chemical Biology 18 (5), 538-546, 2022 | 23 | 2022 |
| One-carbon chemistry of oxalate oxidoreductase captured by X-ray crystallography MI Gibson, PYT Chen, AC Johnson, E Pierce, M Can, SW Ragsdale, ... Proceedings of the National Academy of Sciences 113 (2), 320-325, 2016 | 17 | 2016 |
| Disruption of an oligomeric interface prevents allosteric inhibition of Escherichia coli class Ia ribonucleotide reductase PYT Chen, MA Funk, EJ Brignole, CL Drennan Journal of Biological Chemistry 293 (26), 10404-10412, 2018 | 13 | 2018 |
| XFEL serial crystallography reveals the room temperature structure of methyl-coenzyme M reductase CJ Ohmer, M Dasgupta, A Patwardhan, I Bogacz, C Kaminsky, MD Doyle, ... Journal of Inorganic Biochemistry 230, 111768, 2022 | 9 | 2022 |
| Structural Basis of Stereospecific Vanadium-Dependent Haloperoxidase Family Enzymes in Napyradiomycin Biosynthesis PYT Chen, S Adak, JR Chekan, DK Liscombe, A Miyanaga, P Bernhardt, ... Biochemistry 61 (17), 1844, 2022 | 8 | 2022 |
| Waltzing around cofactors PYT Chen, EC Wittenborn, CL Drennan Elife 5, e13977, 2016 | 3 | 2016 |
| Potent Inhibition of E. coli DXP Synthase by a gem-Diaryl Bisubstrate Analog LB Coco, EM Toci, PYT Chen, CL Drennan, CL Freel Meyers ACS Infectious Diseases 10 (4), 1312, 2024 | 1 | 2024 |
| Mechanistic and Structural Insights into a Divergent PLP-Dependent l-Enduracididine Cyclase from a Toxic Cyanobacterium JL Cordoza, PYT Chen, LR Blaustein, ST Lima, MF Fiore, JR Chekan, ... ACS Catalysis 13 (14), 9817, 2023 | 1 | 2023 |
Catherine DrennanProfessor of Biology and Chemistry, MIT and HHMI Investigator在 mit.edu 的电子邮件经过验证
